Linkage-Disequilibrium Mapping of Disease Genes by Reconstruction of Ancestral Haplotypes in Founder Populations

The Future of Genetic Studies of Complex Human Diseases

1996 • 5,355 citations

Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

1995 • 5,291 citations

Pairwise comparisons of mitochondrial DNA sequences in stable and exponentially growing populations.

1991 • 2,351 citations

Large-Scale Identification, Mapping, and Genotyping of Single-Nucleotide Polymorphisms in the Human Genome

1998 • 2,163 citations

A Mutation in the Interferon-γ –Receptor Gene and Susceptibility to Mycobacterial Infection

1996 • 1,174 citations

A Comparison of Linkage Disequilibrium Measures for Fine-Scale Mapping

1995 • 1,067 citations

A gene encoding a P-type ATPase mutated in two forms of hereditary cholestasis

1998 • 728 citations

A powerful likelihood method for the analysis of linkage disequilibrium between trait loci and one or more polymorphic marker loci.

1995 • 460 citations

Genome screening by searching for shared segments: mapping a gene for benign recurrent intrahepatic cholestasis

1994 • 325 citations

A gene for congenital, recessive deafness DFNB3 maps to the pericentromeric region of chromosome 17

1995 • 222 citations

The theoretical proportion of the donor genome in near-isogenic lines of self-fertilizers bred by backcrossing

1981 • 211 citations

Demographic history and linkage disequilibrium in human populations

1997 • 197 citations

Linkage analysis and family classification under heterogeneity

1983 • 177 citations

Likelihood methods for locating disease genes in nonequilibrium populations.

1995 • 144 citations

Likelihood Analysis of Disequilibrium Mapping, and Related Problems

1998 • 95 citations

Genome Screens Using Linkage Disequilibrium Tests: Optimal Marker Characteristics and Feasibility

1998 • 93 citations

Disequilibrium Mapping: Composite Likelihood for Pairwise Disequilibrium

1996 • 91 citations

Perspectives of identity by descent (IBD) mapping in founder populations

1995 • 89 citations

The distribution of linkage disequilibrium over anonymous genome regions

1995 • 78 citations

Linkage Disequilibrium and Gene Mapping: An Empirical Least-Squares Approach

1998 • 78 citations

Use of linkage disequilibrium approaches to map genes for bipolar disorder in the Costa Rican population

1996 • 75 citations

Distribution of the admixture test for the detection of linkage under heterogeneity

1993 • 75 citations

Cloning and characterization of DXS6673E, a candidate gene for X-linked mental retardation in Xq13.1

1996 • 74 citations

A case—control study of apolipoprotein E genotypes in Alzheimer's disease associated with Down's syndrome

1995 • 66 citations

Novel approaches to linkage mapping

1995 • 62 citations

Genome Scanning for Segments Shared Identical by Descent among Distant Relatives in Isolated Populations

1997 • 33 citations

Genomic analysis I: inheritance units and genetic selection in the rapid discovery of locus linked DNA markers

1986 • 16 citations