Differential chromatid damage induced by 6-thioguanine in CHO cells

A biochemical mechanism for the delayed cytotoxic reaction of 6-mercaptopurine.

1974 • 284 citations

Mechanisms of action of 6-thioguanine, 6-mercaptopurine, and 8-azaguanine.

1975 • 240 citations

Bleomycin-induced damage in prematurely condensed chromosomes and its relationship to cell cycle progression in CHO cells.

1974 • 110 citations

The Cause of G2-Arrest in Chinese Hamster Ovary Cells Treated With Anticancer Drugs2

1976 • 104 citations

The nature of adriamycin-induced cytotoxicity in Chinese hamster cells as revealed by premature chromosome condensation.

1975 • 62 citations

Thioguanine-induced S and G2 blocks and their significance to the mechanism of cytotoxicity.

1980 • 52 citations

Biochemical mechanisms for the synergism between 6-thioguanine and 6-(methylmercapto)purine ribonucleoside in sarcoma 180 cells.

1972 • 47 citations

Utilization of 2'-deoxy-6-thioguanosine 5'-triphosphate in DNA synthesis in vitro by DNA polymerase alpha from calf thymus.

1979 • 41 citations

Induction of premature chromosome condensation in CHO cells fused with polyethylene glycol

1977 • 35 citations

The effects of beta-2'-deoxythioguanosine on survival and progression in mammalian cells.

1971 • 29 citations

Cytotoxic and cytokinetic effects of 1-beta-D-arabinofuranosylcytosine, daunorubicin, and 6-thioguanine on HeLa cells in culture.

1981 • 12 citations

Interactions of 6-thioguanine in B-DNA: Possible mechanism of its mutagenic action

1975 • 8 citations