Functional and morphological effects of interleukin-1? on the perfused rat pancreas

A low-viscosity epoxy resin embedding medium for electron microscopy

1969 • 12,996 citations

Biology of interleukin 1

1988 • 1,547 citations

Tumor Necrosis Factor and Interleuktn-1 in the Serum of Children with Severe Infectious Purpura

1988 • 735 citations

Multiple biological activities of human recombinant interleukin 1.

1986 • 372 citations

Biology of disease: membrane injury and calcium homeostasis in the pathogenesis of coagulative necrosis.

1982 • 316 citations

Glucose stimulates proinsulin biosynthesis by a dose-dependent recruitment of pancreatic beta cells.

1988 • 300 citations

The order of islet microvascular cellular perfusion is B----A----D in the perfused rat pancreas.

1988 • 202 citations

Low-Dose Streptozocin-Induced Diabetes in Mice: Electron Microscopy Reveals Single-Cell Insulitis Before Diabetes Onset

1988 • 151 citations

Mechanisms of pancreatic beta-cell destruction in type I diabetes.

1988 • 145 citations

Interleukin 1 affects glucose homeostasis

1987 • 132 citations

Interaction of β-Cell Activity and IL-1 Concentration and Exposure Time in Isolated Rat Islets of Langerhans

1989 • 129 citations

Role of Biochemical Mediators in Clinical Nutrition and Surgical Metabolism

1988 • 119 citations

Direct stimulation of the adrenal cortex by interleukin-1.

1987 • 117 citations

Studies on the Mechanisms Causing Inhibition of Insulin Secretion in Rat Pancreatic Islets Exposed to Human Interleukin-1β Indicate a Perturbation in the Mitochondrial Function*

1989 • 101 citations

The bimodal effect of interleukin 1 on rat pancreatic beta-cells – stimulation followed by inhibition – depends upon dose, duration of exposure, and ambient glucose concentration

1988 • 101 citations

ULTRASTRUCTURAL STUDIES OF TIME‐COURSE AND CELLULAR SPECIFICITY OF INTERLEUKIN‐1 MEDIATED ISLET CYTOTOXICITY

1987 • 73 citations

Arachidonic acid metabolism in isolated pancreatic islets

1984 • 72 citations

A specific radioimmunoassay for PGE2 using an antibody with high specificity and a sephadex LH-20 microcolumn for the separation of prostaglandins

1976 • 71 citations

Arachidonic acid metabolism in isolated pancreatic islets

1984 • 65 citations

Interleukin‐1‐like immunoreactiveity in pripheral tissues

1987 • 56 citations

Cytolysis by tumor necrosis factor is preceded by a rapid and specific dissolution of microfilaments.

1989 • 45 citations

Monokines and Other Non-Lymphocytic Cytokines

1989 • 28 citations

Cloning and expression of an interleukin‐1β precursor and its conversion to interleukin‐1β

1989 • 26 citations

Mechanism of hyperinsulinemia in endotoxicosis

1980 • 26 citations

Interleukin-1 potentiates glucose stimulated insulin release in the isolated perfused pancreas

1988 • 26 citations

Glucose in the Control of Glucagon Secretion

1983 • 25 citations

Insulin release and pancreatic insulin is reduced in young prediabetic BB rats

1986 • 23 citations

Interleukin-1 Induces Time-Dependent Potentiation in Isolated Rat Islets: Possible Involvement of Phosphoinositide Hydrolysis*

1989 • 19 citations

On the pathogenesis of insulin-dependent diabetes mellitus.

1988 • 18 citations

The relationship between urinary prostaglandin excretion rates and urine flow in conscious rats. Evaluation of the radioimmunoassay by gas chromatography‐mass spectrometry

1983 • 14 citations

Role of the Liver in Endotoxin-Induced Hyperinsulinemia and Hyperglucagonemia in Rats

1983 • 13 citations

Role for calcium in the insulin hypersecretory state of the endotoxic rat pancreas.

1984 • 9 citations

Mechanism of hyperinsulinemia after reticuloendothelial system phagocytosis

1982 • 8 citations

Prostaglandins and Glucagon Secretion

1983 • 4 citations