Salutary effects of aspirin in coronary artery disease are not limited to its platelet inhibitory effects

The pathogenesis of atherosclerosis: a perspective for the 1990s

1993 • 10,730 citations

Inflammation, Aspirin, and the Risk of Cardiovascular Disease in Apparently Healthy Men

1997 • 5,442 citations

The thrombolysis in myocardial infarction (TIMI) trial. Phase I findings

1985 • 3,610 citations

COLLABORATIVE OVERVIEW OF RANDOMIZED TRIALS OF ANTIPLATELET THERAPY .1. PREVENTION OF DEATH, MYOCARDIAL-INFARCTION, AND STROKE BY PROLONGED ANTIPLATELET THERAPY IN VARIOUS CATEGORIES OF PATIENTS

1994 • 3,408 citations

The Thrombolysis in Myocardial Infarction (TIMI) Trial

1985 • 3,078 citations

Collaborative overview of randomised trials of antiplatelet therapy Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients

1994 • 2,993 citations

急性心筋梗塞の疑いのある17187症例におけるストレプトキナーゼ静脈内投与,アスピリン経口投与,上記2つの併用または無処置の無作偽試験 ISIS-2

1988 • 2,760 citations

Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group.

1988 • 2,740 citations

Use of a Monoclonal Antibody Directed against the Platelet Glycoprotein IIb/IIIa Receptor in High-Risk Coronary Angioplasty

1994 • 2,614 citations

Final Report on the Aspirin Component of the Ongoing Physicians' Health Study

1989 • 2,180 citations

Protective Effects of Aspirin against Acute Myocardial Infarction and Death in Men with Unstable Angina

1983 • 1,740 citations

Randomised trial of prophylactic daily aspirin in British male doctors

1988 • 1,178 citations

Aspirin, Sulfinpyrazone, or Both in Unstable Angina

1985 • 1,146 citations

Platelet aggregation in partially obstructed vessels and its elimination with aspirin.

1976 • 765 citations

Risk of myocardial infarction and death during treatment with low dose aspirin and intravenous heparin in men with unstable coronary artery disease

1990 • 751 citations

Risk of myocardial infarction and death during treatment with low dose aspirin and intravenous heparin in men with unstable coronary artery disease

1991 • 702 citations

Collaborative overview of randomised trials of antiplatelet therapy--I: Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. Antiplatelet Trialists' Collaboration.

1994 • 566 citations

Collaborative overview of randomised trials of antiplatelet therapy - II: Maintenance of vascular graft or arterial patency by antiplatelet therapy

1994 • 483 citations

Long-Term Follow-up after Percutaneous Transluminal Coronary Angioplasty

1987 • 381 citations

ASPIRIN AND SECONDARY MORTALITY AFTER MYOCARDIAL INFARCTION

1979 • 361 citations

Aspirin and dipyridamole in the prevention of acute coronary thrombosis complicating coronary angioplasty.

1987 • 334 citations

Interactive Role of Infection, Inflammation and Traditional Risk Factors in Atherosclerosis and Coronary Artery Disease 11This study was supported in part by a Merit Review grant from the Department of Veterans Affairs Central Office, Washington, D.C.

1998 • 323 citations

Acute coronary reocclusion after thrombolysis with recombinant human tissue-type plasminogen activator: prevention by a maintenance infusion.

1986 • 302 citations

Saphenous vein graft patency 1 year after coronary artery bypass surgery and effects of antiplatelet therapy. Results of a Veterans Administration Cooperative Study.

1989 • 292 citations

Neutrophil function in ischemic heart disease.

1989 • 278 citations

Aspirin Inhibits Nuclear Factor–κB Mobilization and Monocyte Adhesion in Stimulated Human Endothelial Cells

1995 • 260 citations

Low-Dose Aspirin Therapy for Chronic Stable Angina

1991 • 227 citations

Local platelet activation causes vasoconstriction of large epicardial canine coronary arteries in vivo. Thromboxane A2 and serotonin are possible mediators.

1989 • 213 citations

Coronary Vasoconstrictor Effect of Indomethacin in Patients with Coronary-Artery Disease

1981 • 206 citations

Effects of Aspirin on Platelet-Neutrophil Interactions

1995 • 182 citations

Recurrence rate after successful coronary angioplasty

1985 • 178 citations

Intimal hyperplasia as a cause of restenosis after percutaneous transluminal coronary angioplasty.

1985 • 168 citations

Platelet thrombus formation on collagen type I. A model of deep vessel injury. Influence of blood rheology, von Willebrand factor, and blood coagulation.

1988 • 160 citations

Increased secretion of tumor necrosis factor-alpha and interferon-gamma by mononuclear leukocytes in patients with ischemic heart disease. Relevance in superoxide anion generation.

1994 • 160 citations

Risk of myocardial infarction and death during treatment with low dose aspirin and intravenous heparin in men with unstable coronary artery disease. The RISC Group.

1990 • 124 citations

Ticlopidine and Aspirin Pretreatment Reduces Coagulation and Platelet Activation During Coronary Dilation Procedures

1997 • 113 citations

Platelet aggregation in aortic and coronary venous blood in patients with and without coronary disease. 3. Role of tachycardia stress and propranolol.

1978 • 113 citations

Aspirin prolongs bleeding time in uremia by a mechanism distinct from platelet cyclooxygenase inhibition.

1987 • 112 citations

Aspirin inhibits platelet function independent of the acetylation of ciclo-oxygenase

1982 • 78 citations

Acute influence of smoking on platelet behaviour, endothelium and plasma lipids and normalization by aspirin

1992 • 77 citations

Antiarrhythmic effects of aspirin during nonthrombotic coronary occlusion.

1978 • 77 citations

Endothelium, coronary vasodilation, and organic nitrates

1995 • 73 citations

A double-blind, placebo-controlled study of ketanserin in patients with Prinzmetal's angina. Evidence against a role for serotonin in the genesis of coronary vasospasm.

1984 • 72 citations

Platelet function studies in coronary heart disease. IX. Increased platelet prostaglandin generation and abnormal platelet sensitivity to prostacyclin and endoperoxide analog in angina pectoris

1980 • 72 citations

Recombinant tissue-type plasminogen activator and immediate angioplasty in acute myocardial infarction. One-year follow-up. The European Cooperative Study Group.

1992 • 70 citations

Collaborative overview of randomised trials of antiplatelet therapy--II: Maintenance of vascular graft or arterial patency by antiplatelet therapy. Antiplatelet Trialists' Collaboration.

1994 • 61 citations

L-NMMA in brain microcirculation of mice is inhibited by blockade of cyclooxygenase and by superoxide dismutase

1992 • 49 citations

Antithrombotic therapy and progression of coronary artery disease. Antiplatelet versus antithrombins.

1992 • 48 citations

Platelet aggregation studies in coronary artery disease

1978 • 48 citations

EFFECTS OF PLATELET INHIBITION ON MYOCARDIAL ISCHAEMIA

1982 • 47 citations

Inhibition by cyclo-oxygenase inhibitors of interleukin-6 production by human peripheral blood mononuclear cells

1991 • 34 citations

Maintenance of patency after thrombolysis in stenotic coronary arteries requires combined inhibition of thrombin and platelets

1993 • 30 citations

Comparison of hypoxia-induced contraction in human, monkey, and dog coronary arteries

1992 • 30 citations

Thrombosis in unstable angina: pathologic aspects.

1987 • 28 citations

Influence of platelet-vessel wall interactions on leukocyte rolling in vivo.

1992 • 23 citations

Piroxicam, indomethacin and aspirin action on a murine fibrosarcoma. Effects on tumour-associated and peritoneal macrophages

1991 • 22 citations

Acetylsalicylic Acid, at High Concentrations, Inhibits Vascular Smooth Muscle Cell Proliferation

1993 • 17 citations

Activated Neutrophils Alter Contractile Properties of the Pulmonary Artery

1992 • 15 citations

Effect of aspirin on circulatory responses to catecholamines

1963 • 15 citations

Effect of acetyl salicylic acid on production and action of leukocyte-derived interferons

1987 • 13 citations

Intracoronary prostacyclin in evolving acute myocardial infarction

1985 • 12 citations

Epoprostenol sodium (prostacyclin) infusion in acute myocardial infarction.

1986 • 11 citations

The Potential Role of Thromboxane Inhibitors in Preventing Myocardial Ischaemic Injury

1990 • 11 citations

The effects of ticlopidine administration at low doses on the incidence of restenosis following percutaneous transluminal coronary angioplasty

1991 • 7 citations

[The effects of ticlopidine administration at low doses on the incidence of restenosis following percutaneous transluminal coronary angioplasty].

1991 • 4 citations

Glycoprotein IIb/IIIa Receptor Blockers in Acute Coronary Syndromes

1997 • 4 citations

[Preventive drug therapy following coronary bypass surgery or PTCA].

1990 • 1 citations