Secretion of a latent neutral proteinase that degrades cartilage proteoglycans by skin and synovial fibroblasts in culture

Further studies on the activation of procollagenase, the latent precursor of bone collagenase. Effects of lysosomal cathepsin B, plasmin and kallikrein, and spontaneous activation

1977 • 389 citations

The release of collagenase as an inactive proenzyme by bone explants in culture

1972 • 236 citations

Evidence that latent collagenases are enzyme-inhibitor complexes

1977 • 223 citations

Metalloproteases of human articular cartilage that digest cartilage proteoglycan at neutral and acid pH.

1976 • 160 citations

Glycosaminoglycan turn-over in articular cartilage

1975 • 120 citations

The simultaneous release by bone explants in culture and the parallel activation of procollagenase and of a latent neutral proteinase that degrades cartilage proteoglycans and denatured collagen

1978 • 91 citations

Degradation of cartilage proteoglycans by a neutral proteinase secreted by rabbit bone-marrow macrophages in culture

1978 • 67 citations

AT LEAST THREE HUMAN NEUTROPHIL LYSOSOMAL PROTEASES ARE CAPABLE OF DEGRADING JOINT CONNECTIVE TISSUES*

1975 • 65 citations

Vertebrate collagenase: Further characterization and the significance of its latent form in vivo

1973 • 63 citations

The secretion of enzymes into the pericellular environment

1975 • 55 citations

Turnover of proteoglycans in guinea pig costal cartilage

1977 • 45 citations

A latent collagenase released by bone and skin explants in culture

1971 • 28 citations

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