The immunologically sensitised renal transplant recipient: the impact of advances in technology on organ allocation and transplant outcome

Significance of the Positive Crossmatch Test in Kidney Transplantation

1969 • 1,453 citations

HYPERACUTE REJECTION OF KIDNEY ALLOGRAFTS, ASSOCIATED WITH PRE-EXISTING HUMORAL ANTIBODIES AGAINST DONOR CELLS

1966 • 897 citations

Poliovirus antibodies in breast-fed infants

1971 • 660 citations

Histocompatibility Testing 1965

1966 • 629 citations

Hyperacute Renal-Homograft Rejection in Man

1968 • 410 citations

FEMORAL NECK FRACTURES.

1964 • 295 citations

INTRAVENOUS IMMUNOGLOBULIN SUPPRESSION OF HLA ALLOANTIBODY IN HIGHLY SENSITIZED TRANSPLANT CANDIDATES AND TRANSPLANTATION WITH A HISTOINCOMPATIBLE ORGAN

1994 • 227 citations

INTRAVENOUS IMMUNOGLOBULIN SUPPRESSION OF HLA ALLOANTIBODY IN HIGHLY SENSITIZED TRANSPLANT CANDIDATES AND TRANSPLANTATION WITH A HISTOINCOMPATIBLE ORGAN

1994 • 227 citations

Simultaneous HLA Class I and Class II Antibodies Screening with Flow Cytometry

1998 • 211 citations

The Impact of HLA Mismatches on the Survival of First Cadaveric Kidney Transplants

1994 • 205 citations

IMMUNOGLOBULIN CLASS AND SPECIFICITY OF ANTIBODIES CAUSING POSITIVE T CELL CROSSMATCHES

1986 • 165 citations

Effect of Antiidiotypic Antibodies to HLA on Graft Survival in Renal-Allograft Recipients

1987 • 151 citations

ENZYME-LINKED IMMUNOASSAY FOR ANTI-HLA ANTIBODIES—AN ALTERNATIVE TO PANEL STUDIES BY LYMPHOCYTOTOXICITY

1993 • 146 citations

CHARACTERIZATION OF LYMPHOCYTOTOXIC ANTIBODIES CAUSING A POSITIVE CROSSMATCH IN RENAL TRANSPLANTATION

1989 • 125 citations

Prevention of hyperacute rejection by removal of antibodies to HLA immediately before renal transplantation

1996 • 117 citations

IMPORTANCE OF MINIMIZING HLA-DR MISMATCH AND COLD PRESERVATION TIME IN CADAVERIC RENAL TRANSPLANTATION

1996 • 98 citations

THE RELATIONSHIP BETWEEN FLOW CYTOMETER CROSSMATCH RESULTS AND SUBSEQUENT REJECTION EPISODES IN CADAVER RENAL ALLOGRAFT RECIPIENTS

1988 • 96 citations

SUCCESSFUL RENAL TRANSPLANTATION IN PATIENTS WITH T-CELL REACTIVITY TO DONOR

1982 • 96 citations

HYPERACUTE AND ACUTE KIDNEY GRAFT REJECTION DUE TO ANTIBODIES AGAINST B CELLS

1992 • 86 citations

HYPERACUTE REJECTION OF HLA-AB-IDENTICAL RENAL ALLOGRAFTS ASSOCIATED WITH B LYMPHOCYTE AND ENDOTHELIAL REACTIVE ANTIBODIES

1982 • 85 citations

CORRELATION OF ELISA-DETECTED IgG AND IgA ANTI-HLA ANTIBODIES IN PRETRANSPLANT SERA WITH RENAL ALLOGRAFT REJECTION1

1996 • 80 citations

THE OCCURRENCE OF CYTOTOXIC AND NON-COMPLEMENT-FIXING ANTIBODIES IN THE CROSSMATCH SERUM OF PATIENTS WITH EARLY ACUTE REJECTION EPISODES

1992 • 76 citations

VARIATIONS OF THE LYMPHOCYTOTOXICITY TEST AN EVALUATION OF SENSITIVITY AND SPECIFICITY

1995 • 72 citations

NO CHILDHOOD

1975 • 71 citations

Laboratory and clinical management of the highly sensitized organ transplant recipient

1989 • 69 citations

Sero-typing of human lymphocyte antigens: Preliminary trials on long-term kidney homograft survivors

1965 • 69 citations

Detection of HLA class I-specific antibodies by the QuikScreen enzyme-linked immunosorbent assay

1997 • 67 citations

MULTISCREEN SERUM ANALYSIS OF HIGHLY SENSITIZED RENAL DIALYSIS PATIENTS FOR ANTIBODIES TOWARD PUBLIC AND PRIVATE CLASS I HLA DETERMINANTS

1990 • 67 citations

IDENTIFICATION OF PATIENTS AT RISK FOR INFERIOR RENAL ALLOGRAFT OUTCOME BY A STRONGLY POSITIVE B CELL FLOW CYTOMETRY CROSSMATCH1

1994 • 61 citations

SPECIFICITY AND Ig CLASS OF PREFORMED ALLOANTIBODIES CAUSING A POSITIVE CROSSMATCH IN RENAL TRANSPLANTATION

1993 • 60 citations

RENAL TRANSPLANTATION AND B-CELL CROSS-MATCHES WITH AUTOANTIBODIES AND ALLOANTIBODIES

1977 • 57 citations

EARLY RENAL GRAFT DYSFUNCTION

1996 • 54 citations

IMPORTANCE OF THE AUTOCONTROL CROSSMATCH IN HUMAN RENAL TRANSPLANTATION

1976 • 54 citations

Hyperacute rejection of a renal allograft in the presence of anti-HLA-Cw5 antibody.

1986 • 52 citations

AUTOANTIBODY AGAINST B LYMPHOCYTES

1977 • 51 citations

EPITOPE SPECIFICITY OF HLA CLASS I ALLOANTIBODIES

1997 • 51 citations

THE PRESENCE OF POSTTRANSPLANT HLA-SPECIFIC IgG ANTIBODIES DETECTED BY ENZYME-LINKED IMMUNOSORBENT ASSAY CORRELATES WITH SPECIFIC REJECTION PATHOLOGIES

1997 • 51 citations

Successful transplantation with a positive T and B cell crossmatch due to autoreactive antibodies

1983 • 50 citations

B CELL ANTIBODIES AND CROSSMATCHING

1980 • 49 citations

DETECTION OF HLA-SPECIFIC ANTIBODIES BY PRA-STAT AND THEIR ASSOCIATION WITH TRANSPLANT OUTCOME

1998 • 48 citations

THE LYMPHOCYTOTOXIC CROSSMATCH TEST IN CLINICAL RENAL TRANSPLANTATION

1983 • 46 citations

HYPERACUTE REJECTION OF A RENAL ALLOGRAFT IN THE PRESENCE OF ANTI-HLA-Cw5 ANTIBODY

1986 • 46 citations

RENAL ALLOGRAFT REJECTION ASSOCIATED WITH PRESENSITIZATION TO HLA-DR ANTIGENS

1981 • 44 citations

DETECTION OF HLA CLASS I- AND CLASS II-SPECIFIC ANTIBODIES BY FLOW CYTOMETRY AND PRA-STAT SCREENING IN RENAL TRANSPLANT RECIPIENTS

1997 • 43 citations

Immunoadsorption of anti-HLA antibodies for highly sensitized patients awaiting renal transplantation

1992 • 42 citations

Flow cytometry PRA, a new test that is highly correlated with graft survival

1992 • 42 citations

EVIDENCE THAT ANTIBODY FORMATION AGAINST A CERTAIN HLA ALLOANTIGEN IS ASSOCIATED NOT WITH A QUANTITATIVE BUT WITH A QUALITATIVE CHANGE IN THE CYTOTOXIC T CELLS RECOGNIZING THE SAME ANTIGEN

1992 • 40 citations

DIFFERENTIAL INHIBITION OF PRIMED ALLOREACTIVE CTLs IN VITRO BY CLINICALLY USED CONCENTRATIONS OF CYCLOSPORINE AND FK506

1993 • 39 citations

THE DEVELOPMENT AND SPECIFICITY OF ANTIIDIOTYPIC ANTIBODIES IN RENAL TRANSPLANT RECIPIENTS RECEIVING SINGLE-DONOR BLOOD TRANSFUSIONS

1989 • 38 citations

HL-A UNRESPONSIVENESS INDUCED BY WEEKLY TRANSFUSIONS OF SMALL ALIQUOTS OF WHOLE BLOOD

1974 • 36 citations

THE USE OF MAGNETIC BEADS COATED WITH SOLUBLE HLA CLASS I OR CLASS II PROTEINS IN ANTIBODY SCREENING AND FOR SPECIFICITY DETERMINATION OF DONOR-REACTIVE ANTIBODIES1

1996 • 36 citations

REACTIVITY OF AUTOLYMPHOCYTOTOXIC ANTIBODIES FROM DIALYSIS PATIENTS WITH LYMPHOCYTES FROM CHRONIC LYMPHOCYTIC LEUKEMIA (CLL) PATIENTS

1978 • 36 citations

IgG ANTIBODIES AGAINST AN HLA ANTIGEN ARE ASSOCIATED WITH ACTIVATED CYTOTOXIC T CELLS AGAINST THIS ANTIGEN, IgM ARE NOT

1994 • 36 citations

DONOR-SPECIFIC B AND T LYMPHOCYTE ANTIBODIES AND KIDNEY GRAFT SURVIVAL

1981 • 35 citations

SOLUBLE HLA ANTIGENS AND ELISA—A NEW TECHNOLOGY FOR CROSSMATCH TESTING1

1995 • 35 citations

Successful kidney transplantation of immunized patients after desensitization with normal human polyclonal immunoglobulins.

1995 • 35 citations

SUCCESSFUL KIDNEY TRANSPLANT IN PATIENT WITH POSITIVE CROSSMATCH DUE TO AUTOANTIBODIES

1976 • 33 citations

Transplantation of highly sensitized patients on the basis of acceptable HLA-A and B mismatches.

1989 • 33 citations

EFFECT OF PROTEIN A IMMUNOADSORPTION ON PANEL LYMPHOCYTE REACTIVITY IN HYPERIMMUNIZED PATIENTS AWAITING A KIDNEY GRAFT

1990 • 33 citations

A highly sensitive, rapid screening method for the detection of antibodies directed against HLA class I and II antigens

1993 • 32 citations

SUCCESSFUL REMOVAL AND PREVENTION OF RESYNTHESIS OF ANTI-HLA ANTIBODY

1984 • 31 citations

An approach to reducing early kidney transplant failure by flow cytometry crossmatching

1987 • 29 citations

Outcome of renal transplantation following a positive cross-match with historical sera: The ASHI survey

1985 • 29 citations

RECURRENT HEMOLYTIC UREMIC SYNDROME IN A RENAL TRANSPLANT RECIPIENT AND REVIEW OF THE LEIDEN EXPERIENCE

1988 • 29 citations

A positive B cell crossmatch due to IgG anti‐HLA‐DQ antibody present at the time of transplantation in a successful renal allograft

1987 • 29 citations

ASSOCIATION OF ANTIIDIOTYPIC ANTIBODY WITH SUCCESSFUL SECOND TRANSPLANT OF A KIDNEY SHARING HLA ANTIGENS WITH THE PREVIOUS HYPERACUTELY REJECTED FIRST KIDNEY

1989 • 28 citations

A RAPID FLOW CYTOMETRY ASSAY FOR HLA ANTIBODY DETECTION USING A POOLED CELL PANEL COVERING 14 SEROLOGICAL CROSSREACTING GROUPS1

1995 • 27 citations

Advances in Transplantation

1994 • 26 citations

Extracorporeal immunoadsorption of anti-HLA antibodies: preliminary clinical experience.

1987 • 25 citations

SUCCESSFUL CADAVER KIDNEY TRANSPLANTATION IN PATIENTS HIGHLY SENSITIZED BY BLOOD TRANSFUSIONS

1985 • 24 citations

Current status of HLA matching in renal transplantation

1992 • 23 citations

SUCCESSFUL KIDNEY TRANSPLANTATION WITH CURRENT-SERA-NEGATIVE/HISTORICAL-SERA-POSTIVE T CELL CROSSMATCH

1984 • 23 citations

Influence of antiidiotypic antibody activity on renal transplant outcome

1991 • 22 citations

SUCCESSFUL TRANSPLANTATION OF CYCLOSPORINE-TREATED ALLOGRAFT RECIPIENTS WITH SEROLOGICALLY POSITIVE HISTORICAL, BUT NEGATIVE PREOPERATIVE, DONOR CROSSMATCHES

1985 • 22 citations

Hyperimmunized patients do not need to wait for an HLA identical donor

1989 • 20 citations

Renal transplantation to sensitized patients: decreased graft survival probability associated with a positive historical crossmatch

1995 • 20 citations

MOST POSITIVE B CELL CROSSMATCHES ARE NOT CAUSED BY ANTI-HLA-DR ANTIBODIES

1980 • 20 citations

A novel strategy for the detection and definition of HLA-specific antibodies in patients awaiting renal transplantation

1998 • 17 citations

THE PROSPECTIVE VALUE OF THE PREOPERATIVE FLOW CYTOMETRIC CROSSMATCH ASSAY IN RENAL TRANSPLANTATION

1990 • 17 citations

A novel strategy for the detection and definition of HLA-specific antibodies in patients awaiting renal transplantation

1998 • 17 citations

The prospective value of the preoperative flow cytometric crossmatch assay in renal transplantation.

1990 • 16 citations

Permissible Mismatches, Acceptable Mismatches and Tolerance: New Trends in Decision Making

1997 • 16 citations

SIX-ANTIGEN-MATCHED TRANSPLANTS

1993 • 16 citations

Production and characterization of human monoclonal lymphocytotoxic autoantibodies from a renal dialysis patient

1991 • 16 citations

Immediate rejection of a HLA-A, B compatible, HLA-DR incompatible kidney with a positive donor-recipient B-cell crossmatch.

1980 • 15 citations

Anti-idiotypic antibodies specific for HLA in heart and kidney allograft recipients

1993 • 15 citations

Five-year results of renal transplantation in highly sensitized recipients

1996 • 14 citations

Successful renal transplantation in the presence of donor specific HLA IgM antibodies.

1995 • 13 citations

POSITIVE T CELL CROSSMATCH WITH STORED RECIPIENT SERA IN CADAVERIC RENAL TRANSPLANTATION

1985 • 12 citations

Five-year results of renal transplantation in highly sensitized recipients

1996 • 12 citations

The association between a positive T and B cell flow cytometry crossmatch and renal transplant failure

1993 • 12 citations

THE EVALUATION AND RELEVANCE OF AUTOLYMPHOCYTOTOXIC ANTIBODY IN THE HIGHLY PRESENSITIZED PATIENT

1987 • 12 citations

Positive crossmatch transplants--safe or not?

1981 • 12 citations

Extra reactivities detected in flow-cytometry-positive, CDC-negative crossmatches are definable HLA specificities.

1987 • 12 citations

Plasma exchange and immunosuppressive therapy before renal transplantation in highly sensitized patients.

1987 • 11 citations

The blood transfusion effect: clinical aspects

1991 • 10 citations

Lack of correlation between IgG T-lymphocyte flow cytometric crossmatches with primary renal allograft outcome

1992 • 10 citations

FAILURE TO DECREASE ANTIBODY LEVELS IN SENSITIZED PATIENTS BY REPEATED TRANSFUSIONS FROM ONE DONOR AND CYCLOSPORINE

1988 • 10 citations

The effect of historical crossmatches and sensitization of renal allograft survival.

1989 • 9 citations

Preexistent anti-HLA-DR antibodies and kidney graft survival.

1979 • 9 citations

Retrospective tests of B-cold lymphocytotoxins and transplant survival at a single center.

1979 • 9 citations

Lack of correlation between IgG T-lymphocyte flow cytometric crossmatches with primary renal allograft outcome

1992 • 8 citations

Role of antibodies to B lymphocytes in renal transplantation.

1977 • 8 citations

THE IMPORTANCE OF SERUM DITHIOTHERITOL TREATMENT IN CROSSMATCHING SELECTION OF PRESENSITIZED KIDNEY TRANSPLANT RECIPIENTS

1990 • 7 citations

Search for anti-idiotypic antibodies in sera of renal transplant recipients.

1987 • 7 citations

Collaborative Transplant Study Kidney Exchange Trial for highly sensitized recipients.

1991 • 7 citations

Anti-idiotypic autoantibodies after donor-specific blood transfusions.

1987 • 6 citations

SUCCESSFUL RENAL TRANSPLANTATION DESPITE WARM B CELL ANTIBODIES

1983 • 6 citations

EFFECT OF FACTORS INHIBITING HLA-DR ANTIBODIES BEFORE TRANSPLANTATION ON KIDNEY GRAFT SURVIVAL

1988 • 5 citations

Anticipation of highly sensitised renal patients’ immunoadsorption requirements by prescreening using protein A minicolumns

1996 • 5 citations

B-cell antibodies and clinical kidney transplantation.

1978 • 5 citations

Relevance of positive crossmatches in renal transplantation.

1992 • 4 citations

ELISA assay for the detection of specific antibodies to class I HLA antigens in transplant patients with panel reactive antibody

1996 • 4 citations

Successful renal transplantation with a positive T-cell cross match caused by IgM antibodies.

1995 • 4 citations

Anticipation of highly sensitised renal patients' immunoadsorption requirements by prescreening using protein A minicolumns

1996 • 4 citations

POSITIVE CROSSMATCHES AGAINST MANDATORILY SHARED KIDNEYS

1992 • 3 citations

Transplant outcome of desensitized recipients after donor-specific transfusion.

1987 • 3 citations

Importance of HLA-A, -B and -DR matching in presensitized kidney transplant recipients.

1988 • 3 citations

Desensitization--which renal allograft recipients are suitable?

1987 • 2 citations

Comparison of dithiothreitol (DTT) treatment and absorption using autologous EBV-transformed lymphoblastoid cell lines for the depletion of autoreactive antibodies.

1989 • 2 citations

PRETRANSPLANT WARM B CELL ANTIBODIES IN RECIPIENTS OF PRIMARY AND RETRANSPLANTED CADAVER RENAL ALLOGRAFTS

1984 • 2 citations

Reduction of anti-HLA antibody using small-dose single-donor blood transfusion.

1987 • 1 citations

Comparison of an ELISA crossmatch (cross-stat) with the NIH and anti-human globulin lymphocytotoxicity assays

1996 • 1 citations

Deleted Work

1955 • 0 citations