A novel ETA‐receptor antagonist, FR 139317, inhibits endothelin‐induced contractions of guinea‐pig pulmonary arteries, but not trachea

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

1988 • 10,786 citations

Some statistical methods useful in circulation research.

1980 • 3,978 citations

SOME QUANTITATIVE USES OF DRUG ANTAGONISTS

1959 • 3,948 citations

Cloning and expression of a cDNA encoding an endothelin receptor

1990 • 2,590 citations

The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes.

1989 • 2,551 citations

Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor

1990 • 2,432 citations

The Role of Endothelium in the Responses of Vascular Smooth Muscle to Drugs

1984 • 937 citations

Biological profiles of highly potent novel endothelin antagonists selective for the ETA receptor

1992 • 880 citations

Primary structure, synthesis, and biological activity of rat endothelin, an endothelium-derived vasoconstrictor peptide.

1988 • 551 citations

pA2 and receptor differentiation: A statistical analysis of competitive antagonism

1979 • 408 citations

Endothelin, a novel endothelium-derived peptide

1989 • 365 citations

Two distinct types of endothelin receptors are present on chick cardiac membranes

1989 • 176 citations

[Ala1,3,11,15]endothelin-1 analogs with ETB agonistic activity

1991 • 156 citations

Two different forms of endothelin receptors in rat lung

1989 • 117 citations

Vascular activities of endothelin‐1 and some alanyl substituted analogues in resistance beds of the rat

1989 • 98 citations

Multiple subtypes of endothelin receptors in porcine tissues: characterization by ligand binding, affinity labeling and regional distribution

1991 • 66 citations

Endothelin receptors cloned, endothelin converting enzyme characterized and pathophysiological roles for endothelin proposed

1991 • 63 citations

Presence of endothelin-1 and endothelin-3 in peripheral tissues and central nervous system of the pig

1991 • 58 citations

Binding of [¹²⁵I]‐endothelin‐1 to rat cerebellar homogenates and its interactions with some analogues

1990 • 52 citations

Detection of endothelium in cerebral blood vessels

1984 • 51 citations

Conformational study of cyclo[D‐Trp‐D‐Asp‐Pro‐D‐Val‐Leu], an endothelin‐A receptor‐selective antagonist

1992 • 47 citations

Analysis of endothelin‐1‐induced contractions of guinea‐pig trachea, pulmonary veins and different types of pulmonary arteries

1990 • 42 citations

Evidence for multiple endothelin receptors in the guinea‐pig pulmonary artery and trachea

1992 • 39 citations

The binding of doxepin to histamine H₁‐preceptors in guinea‐pig and rat brain

1985 • 37 citations

The endothelin explosion. A pathophysiological reality or a biological curiosity?

1990 • 27 citations

A novel endothelin receptor antagonist: studies with FR139317

1992 • 21 citations

The Endothelins

1990 • 11 citations

Two functional endothelin receptors in guinea-pig pulmonary arteries

1991 • 7 citations

Endothelin

1992 • 4 citations