Mice Lacking the Long Splice Variant of the γ2 Subunit of the GABAA Receptor Are More Sensitive to Benzodiazepines

Cerebellar GABAA receptor selective for a behavioural alcohol antagonist

1990 • 536 citations

Benzodiazepine-insensitive mice generated by targeted disruption of the gamma 2 subunit gene of gamma-aminobutyric acid type A receptors.

1995 • 437 citations

Another mechanism for creating diversity in gamma-aminobutyrate type A receptors: RNA splicing directs expression of two forms of gamma 2 phosphorylation site.

1990 • 415 citations

On biological assays involving quantal responses.

1972 • 245 citations

Gene Knockout of the α6 Subunit of the γ-Aminobutyric Acid Type A Receptor: Lack of Effect on Responses to Ethanol, Pentobarbital, and General Anesthetics

1997 • 180 citations

Ethanol potentiation of GABA_A receptors requires phosphorylation of the alternatively spliced variant of the γ2 subunit

1992 • 178 citations

Anesthesia Sensitivity in Mice that Lack the β3 Subunit of the γ-Aminobutyric Acid Type A Receptor

1998 • 159 citations

Functional comparison of the role of gamma subunits in recombinant human gamma-aminobutyric acidA/benzodiazepine receptors.

1993 • 141 citations

Pharmacologic and Behavioral Responses of Inbred C57BL/6J and Strain 129/SvJ Mouse Lines

1999 • 136 citations

Normal electrophysiological and behavioral responses to ethanol in mice lacking the long splice variant of the γ2 subunit of the γ-aminobutyrate type A receptor

1999 • 106 citations

Recombinant GABA_A receptor function and ethanol

1993 • 104 citations

Immunocytochemical localization of gamma 2 short and gamma 2 long subunits of the GABAA receptor in the rat brain

1994 • 94 citations

Anaesthetic concentrations of alcohols potentiate GABAA receptor-mediated currents: lack of subunit specificity

1994 • 86 citations

Ethanol, Flunitrazepam, and Pentobarbital Modulation of GABA_A Receptors Expressed in Mammalian Cells and Xenopus Oocytes

1997 • 78 citations

Differential effects of central nervous system depressants in long-sleep and short-sleep mice.

1986 • 73 citations

Four amino acid exchanges convert a diazepam-insensitive, inverse agonist-preferring GABAA receptor into a diazepam-preferring GABAA receptor

1994 • 71 citations

Anesthetic Potencies of Secondary Alcohol Enantiomers

1987 • 39 citations

BENZODIAZEPINES

1988 • 30 citations

Codon—anticodon pairing A model for interacting codon—anticodon duplexes located at the ribosomal A‐ and P‐sites

1992 • 28 citations

Ligand-dependent effects of ethanol and diethylether at brain benzodiazepine receptors

1992 • 8 citations