Mapping the Domain(s) Critical for the Binding of Human Tumor Necrosis Factor-α to Its Two Receptors

The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death

1994 • 1,920 citations

A graphic method for the determination and presentation of binding parameters in a complex system

1967 • 1,524 citations

Crystal structure of the soluble human 55 kd TNF receptor-human TNFβ complex: Implications for TNF receptor activation

1993 • 1,073 citations

Two TNF receptors

1992 • 1,048 citations

Molecular cloning and expression of a receptor for human tumor necrosis factor

1990 • 973 citations

Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor

1990 • 918 citations

The two different receptors for tumor necrosis factor mediate distinct cellular responses.

1991 • 815 citations

TUMOR NECROSIS, CACHEXIA, SHOCK, AND INFLAMMATION: A COMMON MEDIATOR

1988 • 814 citations

Tumor necrosis factor.

1991 • 568 citations

Effects of Intercistronic Length on the Efficiency of Reinitiation by Eucaryotic Ribosomes

1987 • 540 citations

Structure of tumour necrosis factor

1989 • 512 citations

The structure of tumor necrosis factor-alpha at 2.6 A resolution. Implications for receptor binding.

1989 • 511 citations

The Structure of Tumor Necrosis Factor-α at 2.6 Å Resolution

1989 • 441 citations

Unraveling Function in the TNF Ligand and Receptor Families

1994 • 431 citations

The active form of tumor necrosis factor is a trimer.

1987 • 430 citations

Two Different Cell Types have Different Major Receptors for Human Tumor Necrosis Factor (TNFα)

1989 • 368 citations

The molecular action of tumor necrosis factor-alpha

1991 • 279 citations

Identification of a 60-kD tumor necrosis factor (TNF) receptor as the major signal transducing component in TNF responses.

1990 • 215 citations

Human tumor necrosis factor alpha (TNF alpha) mutants with exclusive specificity for the 55-kDa or 75-kDa TNF receptors.

1993 • 211 citations

Mapping the Lectin-Like Activity of Tumor Necrosis Factor

1994 • 192 citations

Tumor necrosis factor (TNF)-alpha but not TNF-beta induces secretion of colony stimulating factor for macrophages (CSF-1) by human monocytes

1987 • 191 citations

The structure of human lymphotoxin (tumor necrosis factor-beta) at 1.9-A resolution.

1992 • 187 citations

Human TNF mutants with selective activity on the p55 receptor

1993 • 182 citations

Molecular cloning and expression of the type 1 and type 2 murine receptors for tumor necrosis factor.

1991 • 160 citations

Recombinant 55-kDa tumor necrosis factor (TNF) receptor. Stoichiometry of binding to TNF alpha and TNF beta and inhibition of TNF activity.

1991 • 154 citations

Cloning of human tumor necrosis factor (TNF) receptor cDNA and expression of recombinant soluble TNF-binding protein.

1990 • 141 citations

TNF-alpha binds to the N-terminal domain of fibronectin and augments the beta 1-integrin-mediated adhesion of CD4+ T lymphocytes to the glycoprotein.

1994 • 115 citations

Tumor necrosis factors alpha and beta differ in their capacities to generate interleukin 1 release from human endothelial cells.

1987 • 99 citations

Monokines and Other Non-Lymphocytic Cytokines

1989 • 75 citations

Structure-activity studies of human tumour necrosis factors

1994 • 72 citations

Site-directed mutational analysis of human tumor necrosis factor-alpha receptor binding site and structure-functional relationship.

1992 • 69 citations

Molecular weight of recombinant human tumor necrosis factor-alpha.

1987 • 60 citations

Monokines and other nonlymphocytic cytokines

1989 • 43 citations

Diversity of the effect of recombinant tumor necrosis factors alpha and beta on human myelogenous leukemia cell lines

1987 • 31 citations

Reversible subunit dissociation of tumor necrosis factor during hydrophobic interaction chromatography

1988 • 29 citations

Diversity of the effect of recombinant tumor necrosis factors alpha and beta on human myelogenous leukemia cell lines

1987 • 25 citations

Identification of the binding site of 55kda tumor necrosis factor receptor by synthetic peptides

1992 • 24 citations

Antigenic structure of human tumour necrosis factor: Recognition of distinct regions of TNFα by different tumour cell receptors

1991 • 22 citations

A 20 amino acid synthetic peptide of a region from the 55 kDa human TNF receptor inhibits cytolytic and binding activities of recombinant human tumour necrosis factorin vitro

1991 • 17 citations

Deleted Work

1955 • 0 citations