Ubiquitin gene expression in brain and spinal cord in motor neurone disease

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

The yeast polyubiquitin gene is essential for resistance to high temperatures, starvation, and other stresses

1987 • 850 citations

Ubiquitin dependence of selective protein degradation demonstrated in the mammalian cell cycle mutant ts85

1984 • 533 citations

The yeast ubiquitin genes: a family of natural gene fusions.

1987 • 500 citations

Ubiquitin-Mediated Pathways for Intracellular Proteolysis

1987 • 409 citations

Ubiquitin is a heat shock protein in chicken embryo fibroblasts.

1985 • 392 citations

The human ubiquitin multigene family: some genes contain multiple directly repeated ubiquitin coding sequences.

1985 • 355 citations

The yeast ubiquitin gene: head-to-tail repeats encoding a polyubiquitin precursor protein

1984 • 313 citations

Ubiquitin deposits in anterior horn cells in motor neurone disease

1988 • 277 citations

A filamentous inclusion body within anterior horn neurones in motor neurone disease defined by immunocytochemical localisation of ubiquitin

1988 • 226 citations

Nucleotide sequence analysis of a cDNA encoding human ubiquitin reveals that ubiquitin is synthesized as a precursor.

1985 • 196 citations

Structure and expression of ubiquitin genes of Drosophila melanogaster.

1988 • 185 citations

The human ubiquitin gene family: structure of a gene and pseudogenes from the Ub B subfamily

1987 • 157 citations

Cloning and characterisation of the abundant cytoplasmic 7S RNA from mouse cells

1982 • 150 citations

The Chicken Ubiquitin Gene Contains a Heat Shock Promoter and Expresses an Unstable mRNA in Heat-Shocked Cells

1986 • 137 citations

Multiple ubiquitin mRNAs during xenopus laevis development contain tandem repeats of the 76 amino acid coding sequence

1984 • 130 citations

The dynamics of ubiquitin pools within cultured human lung fibroblasts.

1987 • 104 citations

Ubiquitin genes as a paradigm of concerted evolution of tandem repeats

1987 • 100 citations

Amyotrophic Lateral Sclerosis

1988 • 98 citations

The chicken ubiquitin gene contains a heat shock promoter and expresses an unstable mRNA in heat-shocked cells.

1986 • 94 citations

Ubiquitin gene expression in Dictyostelium is induced by heat and cold shock, cadmium, and inhibitors of protein synthesis

1988 • 83 citations

Ubiquitin genes in trypanosomatidae.

1988 • 66 citations

Structure of two developmentally regulated Dictyostelium discoideum ubiquitin genes.

1987 • 43 citations

Complete cDNA sequence of a Dictyostelium ubiquitin with a carboxy‐terminal tail and identification of the protein using an anti‐peptide antibody

1988 • 34 citations

Differential and coordinate regulation of the eukaryotic small molecular weight RNAs.

1981 • 24 citations