Epithelial and Stromal Cathepsin K and CXCL14 Expression in Breast Tumor Progression

Involvement of chemokine receptors in breast cancer metastasis

2001 • 5,203 citations

Tumors: Wounds That Do Not Heal

1986 • 4,202 citations

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

2003 • 1,587 citations

Molecular Definition of Breast Tumor Heterogeneity

2007 • 1,338 citations

Molecular characterization of the tumor microenvironment in breast cancer

2004 • 1,278 citations

Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice

1998 • 900 citations

Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis

2004 • 618 citations

Distinct roles for cysteine cathepsin genes in multistage tumorigenesis

2006 • 531 citations

Distinct epigenetic changes in the stromal cells of breast cancers

2005 • 510 citations

Tissue architecture: the ultimate regulator of breast epithelial function

2003 • 449 citations

Emerging Roles of Cysteine Cathepsins in Disease and their Potential as Drug Targets

2007 • 434 citations

Stromal cells can contribute oncogenic signals

2001 • 326 citations

Cysteine cathepsins in human cancer

2004 • 303 citations

Cystatins

2003 • 296 citations

Molecular markers in ductal carcinoma in situ of the breast.

2003 • 268 citations

A SAGE (serial analysis of gene expression) view of breast tumor progression.

2001 • 242 citations

BRAK/CXCL14 Is a Potent Inhibitor of Angiogenesis and a Chemotactic Factor for Immature Dendritic Cells

2004 • 239 citations

The osteoclast-associated protease cathepsin K is expressed in human breast carcinoma.

1997 • 218 citations

Loss of New Chemokine CXCL14 in Tumor Tissue Is Associated with Low Infiltration by Dendritic Cells (DC), while Restoration of Human CXCL14 Expression in Tumor Cells Causes Attraction of DC Both In Vitro and In Vivo

2005 • 197 citations

A Cathepsin K Inhibitor Reduces Breast Cancer–Induced Osteolysis and Skeletal Tumor Burden

2007 • 194 citations

In Vivo Expression of the Novel CXC Chemokine BRAK in Normal and Cancerous Human Tissue

2000 • 180 citations

Disruption of CXC Motif Chemokine Ligand-14 in Mice Ameliorates Obesity-induced Insulin Resistance

2007 • 163 citations

The chemokine CXCL14 (BRAK) stimulates activated NK cell migration: Implications for the downregulation of CXCL14 in malignancy

2006 • 134 citations

Dual contrasting roles of cysteine cathepsins in cancer progression: Apoptosis versus tumour invasion

2007 • 130 citations

Inhibition of Cysteine Cathepsin Protease Activity Enhances Chemotherapy Regimens by Decreasing Tumor Growth and Invasiveness in a Mouse Model of Multistage Cancer

2007 • 119 citations

Modulation of CXCL14 (BRAK) expression in prostate cancer

2005 • 104 citations

Xenograft models of premalignant breast disease.

2000 • 104 citations

BRAK/CXCL14 expression suppresses tumor growth in vivo in human oral carcinoma cells

2006 • 77 citations

Murine CXCL14 Is Dispensable for Dendritic Cell Function and Localization within Peripheral Tissues

2006 • 67 citations

CXCL14 enhances insulin-dependent glucose uptake in adipocytes and is related to high-fat diet-induced obesity

2007 • 41 citations

Eighteenth Annual Pezcoller Symposium: Tumor Microenvironment and Heterotypic Interactions

2006 • 18 citations