A Prospective Assessment of the Y402H Variant in Complement Factor H, Genetic Variants in C-Reactive Protein, and Risk of Age-Related Macular Degeneration

A New Statistical Method for Haplotype Reconstruction from Population Data

2001 • 7,499 citations

Inflamm‐aging: An Evolutionary Perspective on Immunosenescence

2000 • 4,521 citations

Complement Factor H Polymorphism in Age-Related Macular Degeneration

2005 • 4,314 citations

A Comparison of Bayesian Methods for Haplotype Reconstruction from Population Genotype Data

2003 • 3,515 citations

Case-Control Studies: Design, Conduct, Analysis.

1983 • 2,447 citations

Complement Factor H Polymorphism and Age-Related Macular Degeneration

2005 • 2,387 citations

Complement Factor H Variant Increases the Risk of Age-Related Macular Degeneration

2005 • 2,362 citations

Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

2003 • 1,925 citations

A common haplotype in the complement regulatory gene factor H ( HF1/CFH ) predisposes individuals to age-related macular degeneration

2005 • 1,907 citations

An Integrated Hypothesis That Considers Drusen as Biomarkers of Immune-Mediated Processes at the RPE-Bruch's Membrane Interface in Aging and Age-Related Macular Degeneration

2001 • 1,256 citations

A Comparison of Linkage Disequilibrium Measures for Fine-Scale Mapping

1995 • 1,067 citations

Drusen associated with aging and age‐related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease

2000 • 915 citations

Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk

2005 • 782 citations

Function of C-reactive protein

2000 • 743 citations

Oxidative Damage and Age Related Macular Degeneration

2008 • 566 citations

The Estimation and Interpretation of Attributable Risk in Health Research

1976 • 457 citations

A prospective study of cigarette smoking and age-related macular degeneration in women.

1997 • 386 citations

Strong Association of the Y402H Variant in Complement Factor H at 1q32 with Susceptibility to Age-Related Macular Degeneration

2005 • 362 citations

A Potential Role for Immune Complex Pathogenesis in Drusen Formation

2000 • 349 citations

Progression of Age-Related Macular Degeneration

2005 • 338 citations

Polymorphisms within the C-Reactive Protein (CRP) Promoter Region Are Associated with Plasma CRP Levels

2005 • 320 citations

A Prospective Study of Cigarette Smoking and Risk of Age-Related Macular Degeneration in Men

1996 • 302 citations

Role of redox-regulated transcription factors in inflammation, aging and age-related diseases

2000 • 299 citations

Meta-analysis of genome scans of age-related macular degeneration

2005 • 240 citations

Association of Common CRP Gene Variants with CRP Levels and Cardiovascular Events

2005 • 219 citations

Early age-related maculopathy in the cardiovascular health study

2002 • 184 citations

A common site within factor H SCR 7 responsible for binding heparin, C‐reactive protein and streptococcal M protein

2003 • 163 citations

Candidate gene analysis suggests a role for fatty acid biosynthesis and regulation of the complement system in the etiology of age-related maculopathy

2005 • 156 citations

Body Mass Index and the Incidence of Visually Significant Age-Related Maculopathy in Men

2001 • 148 citations

A novel common single nucleotide polymorphism in the promoter region of the C-reactive protein gene associated with the plasma concentration of C-reactive protein

2004 • 137 citations

Systemic Markers of Inflammation, Endothelial Dysfunction, and Age-Related Maculopathy

2005 • 101 citations

Prospective Cohort Study of Antioxidant Vitamin Supplement Use and the Risk of Age-related Maculopathy

1999 • 75 citations

Logistic regression model for analyzing extended haplotype data

1998 • 74 citations

The relation between C reactive protein and age related macular degeneration in the Cardiovascular Health Study

2005 • 66 citations

Complement factor H Y402H gene polymorphism, C-reactive protein, and risk of incident myocardial infarction, ischaemic stroke, and venous thromboembolism: A nested case–control study

2005 • 57 citations

Chronic Inflammation in Older People: Recognition, Consequences, and Potential Intervention

1997 • 19 citations