Synthesis and Characterization of Polycyclic Aromatic Hydrocarbon o-Quinone Depurinating N7-Guanine Adducts

p53 Mutations in Human Cancers

1991 • 8,133 citations

Preferential Formation of Benzo[ a ]pyrene Adducts at Lung Cancer Mutational Hotspots in P53

1996 • 1,636 citations

The Chemistry of the quinonoid compounds

1974 • 1,320 citations

Quinone chemistry and toxicity

1992 • 732 citations

Polycyclic Hydrocarbons and Carcinogenesis

1985 • 403 citations

Benzo[a]pyrene-nucleic acid derivative found in vivo: structure of a benzo[a]pyrenetetrahydrodiol epoxide-guanosine adduct

1976 • 244 citations

Regio- and stereospecificity of homogeneous 3 alpha-hydroxysteroid-dihydrodiol dehydrogenase for trans-dihydrodiol metabolites of polycyclic aromatic hydrocarbons.

1986 • 136 citations

Expression and Characterization of Four Recombinant Human Dihydrodiol Dehydrogenase Isoforms: Oxidation of trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene to the Activated o-Quinone Metabolite Benzo[a]pyrene-7,8-dione^,

1998 • 134 citations

The reaction of 3, 4-epoxy-1-butene with deoxyguanosine and DNA in vitro: synthesis and characterization of the main adducts

1984 • 124 citations

Synthesis and identification of benzo[a]pyrene-guanine nucleoside adducts formed by electrochemical oxidation and by horseradish peroxidase catalyzed reaction of benzo[a]pyrene with DNA

1988 • 111 citations

Translesional synthesis on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-BPDE (7, 8-dihydroxy-anti-9, 10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene

1993 • 84 citations

Polycyclic aromatic hydrocarbon (PAH) ortho-quinone conjugate chemistry: Kinetics of thiol addition to PAH ortho-quinones and structures of thioether adducts of naphthalene-1,2-dione

1992 • 71 citations

Synthesis of the non-K-region o-quinones and dihydrodiols of polycyclic aromatic hydrocarbons from the corresponding phenols

1980 • 55 citations

Synthesis of non-k-region -quinones of polycyclic aromatic hydrocarbons from cyclic ketones

1982 • 24 citations

Stable Transfection of Dihydrodiol Dehydrogenase in MCF-7 Breast Carcinoma Cells Promotes Polycyclic Aromatic Hydrocarbon-O-Quinone Formation which Leads to Cell Death

2000 • 4 citations