Proliferation, Differentiation and Apoptosis in Villous Trophoblast at 13–41 Weeks of Gestation (Including Observations on Annulate Lamellae and Nuclear Pore Complexes)

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

1992 • 9,540 citations

The Physiology of Reproduction

1988 • 7,765 citations

The efficiency of systematic sampling in stereology and its prediction*

1987 • 3,508 citations

The unbiased estimation of number and sizes of arbitrary particles using the disector

1984 • 2,539 citations

Stereological Methods. Practical methods for biological morphometry

1979 • 2,038 citations

Apoptosis: Mechanisms and Roles in Pathology

1991 • 1,368 citations

Physiology of Reproduction

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The Human Placenta

1970 • 934 citations

Stereological methods. Vol. 1: Practical methods for biological morphometry

1984 • 624 citations

Nuclear changes in apoptosis

1995 • 538 citations

Stereological estimation of the volume‐weighted mean volume of arbitrary particles observed on random sections*

1985 • 486 citations

The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death

1997 • 470 citations

Epithelial stem cells in vivo

1988 • 446 citations

Placental apoptosis in normal human pregnancy

1997 • 405 citations

Villous cytotrophoblast regulation of the syncytial apoptotic cascade in the human placenta

1998 • 399 citations

In situ apoptotic cell labeling by the TUNEL method: improvement and evaluation on cell preparations.

1996 • 369 citations

TUNEL Apoptotic Cell Detection in Tissue Sections: Critical Evaluation and Improvement

1998 • 358 citations

Manual of histological techniques

1985 • 322 citations

Apoptosis is a major mode of cell death caused by ischaemia and ischaemia/reperfusion injury to the rat intestinal epithelium

1998 • 310 citations

If you assume, you can make an ass out of u and me': a decade of the disector for stereological counting of particles in 3D space.

1996 • 287 citations

The new stereological methods for interpreting functional morphology from slices of cells and organs

1991 • 276 citations

Apoptotic changes occur in syncytiotrophoblast of human placental villi where fibrin type fibrinoid is deposited at discontinuities in the villous trophoblast

1996 • 196 citations

Trophoblast deportation in pre‐eclamptic pregnancy

1991 • 193 citations

Proliferation of villous trophoblast of the human placenta in normal and abnormal pregnancies

1991 • 179 citations

Ultrastructure of the normal human placenta

1991 • 171 citations

Annulate Lamellae: A Last Frontier in Cellular Organelles

1992 • 159 citations

Quantitative description of the elaboration and maturation of villi from 10 weeks of gestation to term

1992 • 150 citations

Anatomy and Genesis of the Placenta

2006 • 142 citations

Apoptosis in human chorionic villi and decidua during normal embryonic development and spontaneous abortion in the first trimester

1998 • 141 citations

Apoptotic Cells in the Human Endometrium and Placental Villi: Pitfalls in Applying the TUNEL Method.

1995 • 139 citations

Cell number as a measure of distribution and renewal of epithelial cells in the small intestine of growing and adult rats

1967 • 136 citations

Spontaneous assembly of pore complex-containing membranes ("annulate lamellae") in Xenopus egg extract in the absence of chromatin.

1991 • 133 citations

Trophoblast interaction with fibrin matrix. Epithelialization of perivillous fibrin deposits as a mechanism for villous repair in the human placenta.

1990 • 131 citations

From 13 weeks to term, the trophoblast of human placenta grows by the continuous recruitment of new proliferative units: A study of nuclear number using the disector

1992 • 126 citations

Cell Proliferation in the Gastrointestinal Tract

1981 • 112 citations

Methodological problems in placental morphometry: Apologia for the use of stereology based on sound sampling practice

1988 • 112 citations

Interpretation of syncytial sprouts and bridges in the human placenta

1987 • 111 citations

Placental metabolism and its regulation in health and diabetes

1994 • 111 citations

In vitro cultured human term cytotrophoblast: A model for normal primary epithelial cells demonstrating a spontaneous differentiation programme that requires EGF for extensive development of syncytium

1997 • 104 citations

Syncytial knots and intervillous bridges in the human placenta: an ultrastructural study.

1977 • 97 citations

THE SIGNIFICANCE OF VILLOUS SYNCYTIAL KNOTS IN THE HUMAN PLACENTA

1965 • 94 citations

Biology of trophoblast

1983 • 90 citations

Quantitative structure of the normal human placenta from 10 weeks of gestation to term

1984 • 87 citations

Microscopical morphology of the human placenta and its effects on oxygen diffusion: a morphometric model

1986 • 82 citations

Changes in oxygen diffusive conductances of human placentae during gestation (10–41 weeks) are commensurate with the gain in fetal weight

1993 • 78 citations

Influence of Ischemia and Artificial Perfusion on Placental Ultrastructure and Morphometry

1985 • 75 citations

Classification of human placental villi

1979 • 73 citations

The relation between cell proliferation, differentiation and ultrastructural development in rat intestinal epithelium

1976 • 70 citations

THE ULTRASTRUCTURE OF HUMAN TROPHOBLAST IN SPONTANEOUS AND INDUCED HYPOXIA USING A SYSTEM OF ORGAN CULTURE

1972 • 67 citations

The ultrastructure of human trophoblast in spontaneous and induced hypoxia using a system of organ culture. A comparison with uultrastructural changes in pre-eclampsia and placental insufficiency.

1972 • 67 citations

Fine structure of the paracellular junctions of terminal villous capillaries in the perfused human placeta

1992 • 66 citations

Propidium iodide as a nuclear marker in immunofluorescence. I. Use with tissue and cytoskeleton studies

1981 • 65 citations

Morphological analysis of degeneration and regeneration of syncytiotrophoblast in first trimester placental villi during organ culture

1997 • 65 citations

Does hypercapillarization influence the branching pattern of terminal villi in the human placenta at high altitude?

1996 • 62 citations

Stereology and its impact on our understanding of human placental functional morphology

1997 • 59 citations

Morphogenesis of human placental chorionic villi: cytoskeletal, syncytioskeletal and extracellular matrix proteins

1981 • 57 citations

Proliferative versus hypertrophic growth in tissue subcompartments of human placental villi during gestation.

1994 • 49 citations

High content of a nuclear pore complex protein in cytoplasmic annulate lamellae of Xenopus oocytes.

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Physical randomization of tissue architecture: an alternative to systematic sampling

1982 • 49 citations

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Cell proliferation in the gastrointestinal tract

1982 • 46 citations

The Involvement of Macrophages and Lymphocytes in the Apoptosis of Enterocytes.

1995 • 42 citations

Stereological study of the effect of altitude on the trophoblast cell populations of human term placental villi

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Developmental expression of Ki‐67 antigen and proliferating cell nuclear antigen in macaque placentas

1994 • 39 citations

Structure of human trophoblast:correlation with function

1983 • 37 citations

Recent applications of the new stereology have thrown fresh light on how the human placenta grows and develops its form

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Experimental design and statistics

1967 • 33 citations

Intervillous connections in the mature human placenta: instances of syncytial fusion or section artifacts?

1986 • 32 citations

Syncytial proliferation in normal and toxemic pregnancies.

1967 • 27 citations

Structure and function of the nematosome.

1987 • 22 citations

Nuclear pore clustering is a consistent feature of apoptosis in vitro.

1996 • 18 citations

Further evidence of species variation in mechanisms of epithelial cell loss in mammalian small intestine: ultrastructural studies on the reindeer ( Rangifer tarandus ) and seal ( Phoca groenlandica )

1998 • 11 citations

Oxygen regulates trophoblast and decidual endothelial cell prostanoid production

1995 • 9 citations

Bcl-2 expression and apoptosis in human trophoblast

1997 • 8 citations

Crypt and villous epithelial cells in adult rat small intestine: numerical and volumetric variation along longitudinal and vertical axes.

1994 • 4 citations

DNA laddering, consistent with programmed cell death, is a normal finding in human placentas

1995 • 4 citations

Features of growth of human placental villous trees

1991 • 4 citations

Apoptosis is increased in invasive cytotrophoblasts from preeclamptic placentas in vivo, and cannot be induced by short-term hypoxia in vitro

1997 • 1 citations