Cytogenetic and fluorescence in situ hybridization studies on sporadic and hereditary tumors associated with von Hippel-Lindau syndrome (VHL)

Identification of the von Hippel-Lindau Disease Tumor Suppressor Gene

1993 • 2,906 citations

Von Hippel–Lindau disease maps to the region of chromosome 3 associated with renal cell carcinoma

1988 • 661 citations

Lindau's disease

1964 • 603 citations

Von Hippel-Lindau disease: clinical and pathological manifestations in nine families with 50 affected members

1976 • 302 citations

Interphase and Metaphase Resolution of Different Distances Within the Human Dystrophin Gene

1990 • 260 citations

Specific Genetic Change in Tumors Associated With von Hippel-Lindau Disease

1989 • 222 citations

Von Hippel-Lindau Disease

1976 • 220 citations

Statistical analysis of the two stage mutation model in von Hippel-Lindau disease, and in sporadic cerebellar haemangioblastoma and renal cell carcinoma.

1990 • 170 citations

Localization of the von Hippel-Lindau disease gene to a small region of chromosome 3

1990 • 154 citations

Genetic flanking markers refine diagnostic criteria and provide insights into the genetics of Von Hippel Lindau disease.

1991 • 128 citations

High frequency of monoallelic retinoblastoma gene deletion in B-cell chronic lymphoid leukemia shown by interphase cytogenetics

1993 • 127 citations

Deletion of chromosome 17p loci in breast cancer cells detected by fluorescence in situ hybridization.

1992 • 106 citations

Trisomy 7 and trisomy 10 characterize subpopulations of tumor-infiltrating lymphocytes in kidney tumors and in the surrounding kidney tissue.

1992 • 83 citations

Nonhomologous chromatid exchange in hereditary and sporadic renal cell carcinomas.

1991 • 82 citations

Mapping the Von Hippel — Lindau disease tumour suppressor gene: identification of germline deletions by pulsed field gel electrophoresis

1993 • 63 citations

Proximal 3p deletion in renal cell carcinoma cells from a patient with von Hippel-Lindau disease

1987 • 62 citations

Verification of isochromosome 12p and identification of other chromosome 12 aberrations in gonadal and extragonadal human germ cell tumors by bicolor double fluorescence in situ hybridization

1992 • 61 citations

On the significance of trisomy 7 and sex chromosome loss in renal cell carcinoma

1990 • 54 citations

Genetic linkage between Von Hippel—Lindau disease and three microsatellite polymorphisms refines the localisation of the VHL locus

1993 • 52 citations

Application of fluorescence in situ hybridization in hematological disorders

1992 • 49 citations

Cytogenetic analysis in renal cell carcinoma: correlation with tumor aggressiveness.

1988 • 43 citations

Cytogenetic characterization of renal cell carcinoma in von Hippel-Lindau syndrome

1990 • 41 citations

Cytogenetic abnormalities in tumors of patients with von hippel-lindau disease

1989 • 36 citations

Chromosomes 17 and 22 involved in marker formation in neurofibrosarcoma in von Recklinghausen disease

1990 • 32 citations

3p involvement in a renal cell carcinoma in von Hippel-Lindau syndrome

1988 • 32 citations

FISH: A useful technique in the verification of clonality of random chromosome abnormalities

1993 • 30 citations

Loss of heterozygosity on 3p in a renal cell carcinoma in von Hippel-Lindau syndrome

1989 • 29 citations

Confirmation of linkage in von Hippel-Lindau disease

1990 • 28 citations

Interphase cytogenetics on paraffin sections of malignant pleural mesothelioma

1992 • 27 citations

Cytogenetic studies on three pheochromocytomas derived from patients with von Hippel-Lindau syndrome

1989 • 27 citations

The isolation of a yeast artificial chromosome (YAC) contig extending for 2 megabases in the vicinity of the Von Hippel Lindau disease gene

1993 • 9 citations

Del(3p)(p13p21) in renal cell adenoma and del(4p)(p14) in bilateral renal cell carcinoma in two unrelated patients with von Hippel-Lindau disease

1990 • 8 citations

Heterochromatic variants and their association with neoplasias: V. Non-Hodgkin's lymphomas

1988 • 8 citations