Listeria-based cancer vaccines that segregate immunogenicity from toxicity

Effector and memory T-cell differentiation: implications for vaccine development

2002 • 1,757 citations

CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes

2003 • 1,623 citations

Programmed contraction of CD8+ T cells after infection

2002 • 586 citations

Apoptosis facilitates antigen presentation to T lymphocytes through MHC-I and CD1 in tuberculosis

2003 • 526 citations

Early Programming of T Cell Populations Responding to Bacterial Infection

2000 • 492 citations

A single amino acid in E-cadherin responsible for host specificity towards the human pathogen Listeria monocytogenes

1999 • 473 citations

Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies

1995 • 473 citations

Construction, Characterization, and Use of TwoListeria monocytogenesSite-Specific Phage Integration Vectors

2002 • 458 citations

Dual roles of plcA in Listeria monocytogenes pathogenesis

1993 • 452 citations

Mice Lacking the Type I Interferon Receptor Are Resistant to Listeria monocytogenes

2004 • 436 citations

Adoptive transfer of immunity to Listeria monocytogenes. The influence of in vitro stimulation on lymphocyte subset requirements.

1987 • 387 citations

The immunodominant major histocompatibility complex class I-restricted antigen of a murine colon tumor derives from an endogenous retroviral gene product.

1996 • 386 citations

What messenger RNA capping tells us about eukaryotic evolution

2002 • 351 citations

Enhanced Antigen-Specific Antitumor Immunity with Altered Peptide Ligands that Stabilize the MHC-Peptide-TCR Complex

2000 • 312 citations

Innate recognition of bacteria by a macrophage cytosolic surveillance pathway

2002 • 282 citations

Invasion of mammalian cells by Listeria monocytogenes: functional mimicry to subvert cellular functions

2002 • 270 citations

Expression of the Listeria monocytogenes EGD inlA and inlB genes, whose products mediate bacterial entry into tissue culture cell lines, by PrfA-dependent and -independent mechanisms

1995 • 259 citations

Compartmentalization of Bacterial Antigens: Differential Effects on Priming of CD8 T Cells and Protective Immunity

1998 • 228 citations

Differentiating between Memory and Effector Cd8 T Cells by Altered Expression of Cell Surface O-Glycans

2000 • 207 citations

The immunodominant major histocompatibility complex class I-restricted antigen of a murine colon tumor derives from an endogenous retroviral gene product

1996 • 206 citations

Rapid Cytotoxic T Lymphocyte Activation Occurs in the Draining Lymph Nodes After Cutaneous Herpes Simplex Virus Infection as a Result of Early Antigen Presentation and Not the Presence of Virus

2002 • 191 citations

Induction of Immunity to Antigens Expressed by Recombinant Adeno-Associated Virus Depends on the Route of Administration

1999 • 168 citations

A Novel Approach of Direct Ex Vivo Epitope Mapping Identifies Dominant and Subdominant CD4 and CD8 T Cell Epitopes from Listeria monocytogenes

2001 • 164 citations

Delivery of a viral antigen to the class I processing and presentation pathway by Listeria monocytogenes.

1994 • 132 citations

Dissemination ofListeria monocytogenesby Infected Phagocytes

1999 • 119 citations

IFN-γ Can Promote Tumor Evasion of the Immune System In Vivo by Down-Regulating Cellular Levels of an Endogenous Tumor Antigen

2000 • 113 citations

Entry of Listeria monocytogenes into Neurons Occurs by Cell-to-Cell Spread: an In Vitro Study

1998 • 106 citations

Listeria monocytogenes-Infected Human Dendritic Cells: Uptake and Host Cell Response

2000 • 99 citations

Primary and secondary immune responses to Listeria monocytogenes

1996 • 88 citations

Listeria monocytogenes as a Vaccine Vector: Virulence Attenuation or Existing Antivector Immunity Does Not Diminish Therapeutic Efficacy

2004 • 87 citations

Immunization with a tumor-associated CTL epitope plus a tumor-related or unrelated Th1 helper peptide elicits protective CTL immunity

2001 • 85 citations

Immunization against endogenous retroviral tumor-associated antigens.

2001 • 82 citations

Recombinant Listeria monocytogenes vaccination eliminates papillomavirus-induced tumors and prevents papilloma formation from viral DNA

1997 • 76 citations

Dendritic cells genetically engineered to simultaneously express endogenous tumor antigen and granulocyte macrophage colony-stimulating factor elicit potent therapeutic antitumor immunity.

2002 • 51 citations

Recombinant Listeria monocytogenes cancer vaccines

1996 • 45 citations

Internalin B promotes the replication of Listeria monocytogenes in mouse hepatocytes

1997 • 42 citations

Production of IL-12 and IL-18 in human dendritic cells upon infection byListeria monocytogenes

2003 • 37 citations