Novel Immunomodulator FTY720 Is Phosphorylated in Rats and Humans To Form a Single Stereoisomer. Identification, Chemical Proof, and Biological Characterization of the Biologically Active Species and Its Enantiomer

Alteration of Lymphocyte Trafficking by Sphingosine-1-Phosphate Receptor Agonists

2002 • 1,655 citations

Regulation of Mitochondrial Biogenesis in Skeletal Muscle by CaMK

2002 • 659 citations

FTY720, a Novel Immunosuppressant, Induces Sequestration of Circulating Mature Lymphocytes by Acceleration of Lymphocyte Homing in Rats. I. FTY720 Selectively Decreases the Number of Circulating Mature Lymphocytes by Acceleration of Lymphocyte Homing

1998 • 586 citations

FTY720: Sphingosine 1-Phosphate Receptor-1 in the Control of Lymphocyte Egress and Endothelial Barrier Function

2004 • 462 citations

Mice Deficient in Sphingosine Kinase 1 Are Rendered Lymphopenic by FTY720

2004 • 439 citations

Phosphorylation of the Immunomodulatory Drug FTY720 by Sphingosine Kinases

2003 • 427 citations

Synthesis and Immunosuppressive Activity of 2-Substituted 2-Aminopropane-1,3-diols and 2-Aminoethanols

2000 • 214 citations

FTY720: ALTERED LYMPHOCYTE TRAFFIC RESULTS IN ALLOGRAFT PROTECTION

2001 • 175 citations

A High-Performance Liquid Chromatographic Method to Measure Sphingosine 1-Phosphate and Related Compounds from Sphingosine Kinase Assays and Other Biological Samples

2000 • 103 citations

Synthesis and biological evaluation of 2,2-disubstituted 2-aminoethanols: analogues of FTY720

1998 • 58 citations

Ring-chain tautomerism and other versatile behaviour of 1,4-diimino- and 1,2-phenylene derivatives of some C-substituted serinols

2002 • 22 citations

Synthesis Alerts 11/98

1998 • 1 citations