Dimerization Is Required for the Activity of the Protein Histidine Kinase CheA That Mediates Signal Transduction in Bacterial Chemotaxis

Escherichia Coli and Salmonella: Typhimurium Cellular and Molecular Biology

1987 • 4,385 citations

Escherichia coli and Salmonella typhimurium: Cellular and molecular biology

1988 • 3,957 citations

Enzyme kinetics; behavior and analysis of rapid equilibrium and steady state enzyme systems

1994 • 3,007 citations

COMMUNICATION MODULES IN BACTERIAL SIGNALING PROTEINS

1992 • 1,449 citations

Enzyme Kinetics Behavior and analysis of rapid equilibrium and steady state enzyme systems

1975 • 1,447 citations

Phosphorylation of three proteins in the signaling pathway of bacterial chemotaxis

1988 • 550 citations

Phosphorylation of bacterial response regulator proteins by low molecular weight phospho-donors.

1992 • 475 citations

Phosphorylation-dependent binding of a signal molecule to the flagellar switch of bacteria.

1993 • 425 citations

Assembly of an MCP receptor, CheW, and kinase CheA complex in the bacterial chemotaxis signal transduction pathway

1992 • 333 citations

Histidine phosphorylation and phosphoryl group transfer in bacterial chemotaxis

1988 • 316 citations

Identification of the site of phosphorylation of the chemotaxis response regulator protein, CheY

1989 • 303 citations

Transmembrane signal transduction in bacterial chemotaxis involves ligand-dependent activation of phosphate group transfer.

1989 • 300 citations

Signal transduction in the phosphate regulon of Escherichia coli involves phosphotransfer between PhoR and PhoB proteins

1989 • 271 citations

Assembly and function of a quaternary signal transduction complex monitored by surface plasmon resonance

1993 • 252 citations

Crosstalk between bacterial chemotaxis signal transduction proteins and regulators of transcription of the Ntr regulon: evidence that nitrogen assimilation and chemotaxis are controlled by a common phosphotransfer mechanism.

1988 • 217 citations

Reconstitution of the bacterial chemotaxis signal transduction system from purified components

1991 • 211 citations

Protein phosphorylation is involved in bacterial chemotaxis.

1987 • 198 citations

Sensory transduction in bacterial chemotaxis involves phosphotransfer between CHE proteins

1988 • 181 citations

Signal transduction in bacteria: CheW forms a reversible complex with the protein kinase CheA.

1991 • 180 citations

The dynamics of protein phosphorylation in bacterial chemotaxis

1990 • 173 citations

Overlapping genes at the cheA locus of Escherichia coli.

1980 • 163 citations

Intermolecular complementation between two defective mutant signal-transducing receptors of Escherichia coli.

1991 • 160 citations

Mechanism of autophosphorylation of Escherichia coli nitrogen regulator II (NRII or NtrB): trans-phosphorylation between subunits

1993 • 158 citations

Homologies between the Salmonella typhimurium CheY protein and proteins involved in the regulation of chemotaxis, membrane protein synthesis, and sporulation.

1985 • 156 citations

CheA protein, a central regulator of bacterial chemotaxis, belongs to a family of proteins that control gene expression in response to changing environmental conditions.

1988 • 149 citations

Intermolecular complementation of the kinase activity of CheA

1993 • 129 citations

Crystal Structure of Myxococcus xanthus Nucleoside Diphosphate Kinase and its Interaction with a Nucleotide Substrate at 2·0 Å Resolution

1993 • 121 citations

Expression of CheA fragments which define domains encoding kinase, phosphotransfer, and CheY binding activities

1993 • 117 citations

Transmembrane signaling by the aspartate receptor: Engineered disulfides reveal static regions of the subunit interface

1995 • 94 citations

Cross talk to the phosphate regulon of Escherichia coli by PhoM protein: PhoM is a histidine protein kinase and catalyzes phosphorylation of PhoB and PhoM-open reading frame 2

1990 • 91 citations

Adenosine 5'-diphosphate binding and the active site of nucleoside diphosphate kinase

1994 • 89 citations

Tandem translation starts in the cheA locus of Escherichia coli

1991 • 84 citations

Sugar transport by the bacterial phosphotransferase system. Structural and thermodynamic domains of enzyme I of Salmonella typhimurium.

1991 • 81 citations

The carboxy-terminal portion of the CheA kinase mediates regulation of autophosphorylation by transducer and CheW

1993 • 80 citations

X-ray structure of nucleoside diphosphate kinase complexed with thymidine diphosphate and Mg2+ at 2-.ANG. resolution

1994 • 76 citations

The short form of the CheA protein restores kinase activity and chemotactic ability to kinase-deficient mutants.

1993 • 70 citations

Kinetics of CheA Autophosphorylation and Dephosphorylation Reactions

1994 • 54 citations

Identification of a possible nucleotide binding site in CheW, a protein required for sensory transduction in bacterial chemotaxis.

1987 • 45 citations

Sugar transport by the bacterial phosphotransferase system. Characterization of the Escherichia coli enzyme I monomer/dimer equilibrium by fluorescence anisotropy.

1994 • 39 citations

pH dependence of CheA autophosphorylation in Escherichia coli

1994 • 25 citations

31P NMR chemical shifts of phosphate covalently bound to proteins

1984 • 20 citations