Activation And Deactivation Of Quinones Catalyzed By Dt-Diaphorase. Evidence For Bioreductive Activation Of Diaziquone (Azq) In Human Tumor Cells And Detoxification Of Benzene Metabolites In Bone Marrow Stroma

The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes. A study of the implications of oxidative stress in intact cells.

1982 • 893 citations

Increase of NAD(P)H:quinone reductase by dietary antioxidants: possible role in protection against carcinogenesis and toxicity.

1980 • 757 citations

DT-diaphorase as a quinone reductase: A cellular control device against semiquinone and superoxide radical formation

1982 • 530 citations

[56] DT diaphorase

1967 • 521 citations

Metabolism and reactions of quinoid anticancer agents

1987 • 273 citations

Toxicology of the blood and bone marrow

1985 • 107 citations

DT-diaphorase and peroxidase influence the covalent binding of the metabolites of phenol, the major metabolite of benzene.

1984 • 93 citations

Metabolic activation of phenol by human myeloperoxidase and horseradish peroxidase.

1986 • 89 citations

Effect of superoxide dismutase on the autoxidation of various hydroquinones—A possible role of superoxide dismutase as a superoxide: Semiquinone oxidoreductase

1988 • 87 citations

Potential bioreductive alkylating agents. 2. Antitumor effect and biochemical studies of naphthoquinone derivatives

1973 • 80 citations

Oxidation of catechol by horseradish peroxidase and human leukocyte peroxidase: Reactions of o-benzoquinone and o-benzosemiquinone*1

1988 • 74 citations

The diffusion of a tumour-specific monoclonal antibody in lymphoma infiltrated spleen

1987 • 60 citations

In vitro effects of benzene metabolites on mouse bone marrow stromal cells

1984 • 59 citations

Macrophage regulation of myelopoiesis is altered by exposure to the benzene metabolite hydroquinone

1989 • 58 citations

Mechanisms of DNA strand breakage and interstrand cross-linking by diaziridinylbenzoquinone (diaziquone) in isolated nuclei from human cells.

1984 • 56 citations

DNA strand scission and cross-linking by diaziridinylbenzoquinone (diaziquone) in human cells and relation to cell killing.

1984 • 51 citations

Mechanism(s) of bioreductive activation

1989 • 46 citations

Bioactivation of catechol in rat and human bone marrow cells

1988 • 41 citations

Mechanism for the Reductive Activation of Diaziquone

1985 • 35 citations

Alkylation of DNA by the new anticancer agent 3,6-diaziridinyl-2,5-bis(carboethoxyamino)-1,4-benzoquinone (AZQ)

1984 • 34 citations

Are reduced quinones necessarily involved in the antitumour activity of quinone drugs?

1987 • 30 citations

Reductive activation of diaziquone and possible involvement of free radicals and the hydroquinone dianion.

1986 • 27 citations

2,3,5-Tris-et̊hylenimino-1,4-benzoquinone (Trenimon): Some chemical and biological properties

1973 • 23 citations

Characterization of DNA damage and cytotoxicity induced in two human colon carcinoma cell lines by cyclodisone.

1989 • 7 citations