The Expression of Desmoglein Isoforms in Cultured Human Keratinocytes Is Regulated by Calcium, Serum, and Protein Kinase C

Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene

1985 • 1,836 citations

INTERMEDIATE FILAMENTS: Structure, Dynamics, Function and Disease

1994 • 1,408 citations

Calcium-Regulated Differentiation of Normal Human Epidermal Keratinocytes in Chemically Defined Clonal Culture and Serum-Free Serial Culture

1983 • 1,088 citations

Changes in keratin gene expression during terminal differentiation of the keratinocyte

1980 • 1,059 citations

Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion

1991 • 1,014 citations

Immunolocalization of keratin polypeptides in human epidermis using monoclonal antibodies

1982 • 777 citations

Regulation of terminal differentiation of cultured human keratinocytes by vitamin A

1981 • 756 citations

Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultured from human squamous cell carcinomas.

1981 • 743 citations

Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in vitro.

1989 • 569 citations

The mesothelial keratins: A new family of cytoskeletal proteins identified in cultured mesothelial cells and nonkeratinizing epithelia

1982 • 523 citations

Targeted Disruption of the Pemphigus Vulgaris Antigen (Desmoglein 3) Gene in Mice Causes Loss of Keratinocyte Cell Adhesion with a Phenotype Similar to Pemphigus Vulgaris

1997 • 428 citations

Calcium regulation of cell-cell contact and differentiation of epidermal cells in culture *1An ultrastructural study

1983 • 370 citations

Calcium-induced reorganization of desmosomal components in cultured human keratinocytes.

1984 • 300 citations

Nomenclature of the desmosomal cadherins.

1993 • 292 citations

Coordinate changes in gene expression which mark the spinous to granular cell transition in epidermis are regulated by protein kinase C.

1993 • 256 citations

Identification of the Ubiquitous Human Desmoglein, Dsg2, and the Expression Catalogue of the Desmoglein Subfamily of Desmosomal Cadherins

1994 • 243 citations

Pemphigus Vulgaris Antigen (Desmoglein 3) Is Localized in the Lower Epidermis, the Site of Blister Formation in Patients

1996 • 206 citations

Intermediate filaments and the initiation of desmosome assembly.

1985 • 175 citations

Specific protein kinase C isozymes mediate the induction of keratinocyte differentiation markers by calcium.

1995 • 171 citations

Complexity and expression patterns of the desmosomal cadherins.

1992 • 162 citations

Stratification-related expression of isoforms of the desmosomal cadherins in human epidermis

1993 • 159 citations

Organization of desmosomal plaque proteins in cells growing at low calcium concentrations.

1988 • 133 citations

Structural analysis and expression of human desmoglein: a cadherin-like component of the desmosome

1991 • 131 citations

Regulation of desmosome assembly in epithelial cells: kinetics of synthesis, transport, and stabilization of desmoglein I, a major protein of the membrane core domain.

1989 • 130 citations

Pemphigus vulgaris antigen, a desmoglein type of cadherin, is localized within keratinocyte desmosomes

1993 • 116 citations

Pemphigus IgG Activates and Translocates Protein Kinase C from the Cytosol to the Particulate/Cytoskeleton Fractions in Human Keratinocytes

1997 • 115 citations

Bryostatin 1 protects protein kinase C-delta from down-regulation in mouse keratinocytes in parallel with its inhibition of phorbol ester-induced differentiation.

1994 • 114 citations

Protein Kinase C Regulates Keratinocyte Transglutaminase (TGK) Gene Expression in Cultured Primary Mouse Epidermal Keratinocytes Induced to Terminally Differentiate by Calcium

1994 • 105 citations

Distinct desmocollin isoforms occur in the same desmosomes and show reciprocally graded distributions in bovine nasal epidermis.

1996 • 102 citations

Immunological identification and characterization of the desmosomal cadherin Dsg2 in coupled and uncoupled epithelial cells and in human tissues

1996 • 96 citations

Definition by specific antisense oligonucleotides of a role for protein kinase Cα in expression of differentiation markers in normal and neoplastic mouse epidermal keratinocytes

1997 • 96 citations

Patterns of desmocollin synthesis in human epithelia: immunolocalization of desmocollins 1 and 3 in special epithelia and in cultured cells.

1996 • 96 citations

Increased expression of keratin 16 causes anomalies in cytoarchitecture and keratinization in transgenic mouse skin.

1994 • 94 citations

Pemphigus Vulgaris and Pemphigus Foliaceus Sera Show an Inversely Graded Binding Pattern to Extracellular Regions of Desmosomes in Different Layers of Human Epidermis

1995 • 94 citations

Analysis of Desmosomal Cadherin–Adhesive Function and Stoichiometry of Desmosomal Cadherin-Plakoglobin Complexes

1996 • 89 citations

Pemphigus Sera Recognize Conformationally Sensitive Epitopes in the Amino-Terminal Region of Desmoglein-1

1995 • 87 citations

Pemphigus: autoimmunity to epidermal cell adhesion molecules.

1996 • 84 citations

Structure and assembly of desmosome junctions: biosynthesis and turnover of the major desmosome components of Madin-Darby canine kidney cells in low calcium medium.

1987 • 81 citations

The bovine desmocollin family: a new gene and expression patterns reflecting epithelial cell proliferation and differentiation.

1994 • 77 citations

The Desmocollins of Human Foreskin Epidermis: Identification and Chromosomal Assignment of a Third Gene and Expression Patterns of the Three Isoforms

1995 • 74 citations

Monoclonal antibody to desmosomal glycoprotein 1—A new epithelial marker for diagnostic pathology

1987 • 66 citations

Protein Kinase C in Normal Human Epidermal Keratinocytes During Proliferation and Calcium-Induced Differentiation

1992 • 64 citations

Filaggrin production by cultured human epidermal keratinocytes and its regulation by retinoic acid

1990 • 58 citations

Identification of a Calcium-Inducible, Epidermal-Specific Regulatory Element in the 3'-Flanking Region of the Human Keratin 1 Gene

1993 • 55 citations

Expression of theSPRRCornification Genes Is Differentially Affected by Carcinogenic Transformation

1997 • 49 citations

Abnormal desmoglein expression by squamous cell carcinoma cells.

1996 • 47 citations

Expression of the “Skin-Type” Desmosomal Cadherin DSC1 Is Closely Linked to the Keratinization of Epithelial Tissues During Mouse Development

1996 • 46 citations

Molecular Biology of Desmosomes and Hemidesmosomes

1994 • 46 citations

Tandem arrangement of the closely linked desmoglein genes on human chromosome 18

1995 • 40 citations

The Effect of Retinoic Acid on the Expression of Pemphigus and Pemphigoid Antigens in Cultured Human Keratinocytes

1984 • 40 citations

Differential expression of desmosomal glycoproteins in keratoacanthoma and squamous cell carcinoma of the skin: an immunohistochemical aid to diagnosis.

1996 • 37 citations

Expression of Distinct Desmocollin Isoforms in Human Epidermis

1993 • 36 citations

Characterisation of a desmocollin isoform (bovine dsc3) exclusively expressed in lower layers of stratified epithelia

1995 • 34 citations

Desmoplakin expression and distribution in cultured rat bladder epithelial cells of varying tumorigenic potential

1991 • 28 citations

Plasminogen Activators in Epithelial Biology

1991 • 22 citations

Differential modulation of human fibroblast and keratinocyte growth by the protein kinase C inhibitor GF 109203X.

1994 • 22 citations

Defective Cell-Cell Adhesion in the Epidermis

2007 • 14 citations

Expression of desmoglein I in squamous cell carcinoma of the esophagus

1994 • 13 citations

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