Divalent Cation-, Nucleotide-, and Polymerization-Dependent Changes in the Conformation of Subdomain 2 of Actin

The Regulation of Rabbit Skeletal Muscle Contraction

1971 • 4,491 citations

Atomic structure of the actin: DNase I complex

1990 • 1,897 citations

Atomic model of the actin filament

1990 • 1,657 citations

The structure of crystalline profilin–β-actin

1993 • 662 citations

Structure of gelsolin segment 1-actin complex and the mechanism of filament severing

1993 • 574 citations

Refinement of the F-Actin Model against X-ray Fiber Diffraction Data by the Use of a Directed Mutation Algorithm

1993 • 503 citations

The measurement of actin concentration in solution: A comparison of methods

1974 • 340 citations

Actin: protein structure and filament dynamics.

1991 • 309 citations

The Initial Phosphate Burst in ATP Hydrolysis by Myosin and Subfragment-1 as Studied by a Modified Malachite Green Method for Determination of Inorganic Phosphate

1986 • 299 citations

The Structure of an Open State of β-Actin at 2.65 Å Resolution

1996 • 211 citations

Mechanism of action of phalloidin on the polymerization of muscle actin

1981 • 207 citations

A Conformational Change in the Actin Subunit Can Change the Flexibility of the Actin Filament

1993 • 203 citations

Amine specificity in transpeptidation. Inhibition of fibrin cross-linking

1968 • 163 citations

Direct evidence for ADP-inorganic phosphate-F-actin as the major intermediate in ATP-actin polymerization. Rate of dissociation of inorganic phosphate from actin filaments

1986 • 160 citations

Probing the mechanism of ATP hydrolysis on F-actin using vanadate and the structural analogs of phosphate BeF-3 and A1F-4.

1988 • 157 citations

Normal modes as refinement parameters for the F-actin model

1995 • 147 citations

Structural basis for the destabilization of F-actin by phosphate release following ATP hydrolysis

1992 • 142 citations

Tightly-bound divalent cation of actin

1992 • 140 citations

Localization of the tightly bound divalent‐cation‐dependent and nucleotide‐dependent conformation changes in G‐actin using limited proteolytic digestion

1993 • 139 citations

Normal Mode Analysis of G-actin

1993 • 134 citations

Phalloidin enhances actin assembly by preventing monomer dissociation.

1984 • 130 citations

A Correlative Analysis of Actin Filament Assembly, Structure, and Dynamics

1997 • 121 citations

Dynamic properties of actin. Structural changes induced by beryllium fluoride.

1994 • 103 citations

Domain motions in actin 1 1Edited by D. Rees

1998 • 101 citations

Structural connectivity in actin: effect of C-terminal modifications on the properties of actin

1994 • 96 citations

Nucleotide binding to actin. Cation dependence of nucleotide dissociation and exchange rates.

1993 • 95 citations

Subtilisin-cleaved actin: polymerization and interaction with myosin subfragment 1

1989 • 90 citations

Studies on the bound calcium of actin

1962 • 88 citations

Selective Carbethoxylation of the Histidine Residues of Actin by Diethylpyrocarbonate

1974 • 85 citations

A novel actin label: a fluorescent probe at glutamine-41 and its consequences

1988 • 82 citations

The mechanisms of ATP hydrolysis accompanying the polymerization of Mg-actin and Ca-actin.

1987 • 81 citations

The actin/actin interactions involving the N‐terminus of the DNase‐I‐binding loop are crucial for stabilization of the actin filament

1993 • 76 citations

High affinity binding of divalent cation to actin monomer is much stronger than previously reported

1986 • 70 citations

Proteolytic removal of three C-terminal residues of actin alters the monomer-monomer interactions

1993 • 65 citations

Tight binding of divalent cations to monomeric actin. Binding kinetics support a simplified model.

1987 • 59 citations

Conformational changes in subdomain 2 of G-actin: fluorescence probing by dansyl ethylenediamine attached to Gln-41

1995 • 58 citations

Long-range conformational effects of proteolytic removal of the last three residues of actin

1995 • 55 citations

Studies on Actin

1961 • 55 citations

Effects of the type of divalent cation, Ca2+ or Mg2+, bound at the high-affinity site and of the ionic composition of the solution on the structure of F-actin

1996 • 54 citations

The tightly bound divalent cation regulates actin polymerization

1983 • 53 citations

Differences in G-actin containing bound ATP or ADP: the magnesium-induced conformational change requires ATP

1985 • 52 citations

Presence of oligomers at subcritical actin concentrations

1985 • 48 citations

A reversible conformational transition in muscle actin is caused by nucleotide exchange and uncovers cysteine in position 10.

1991 • 47 citations

Nucleotide in monomeric actin regulates the reactivity of the thiol groups

1984 • 41 citations

Kinetics of nucleotide and metal ion interaction with G-actin

1988 • 39 citations

Structural changes in subdomain 2 of G-actin observed by fluorescence spectroscopy

1996 • 39 citations

Optical Rotatory Dispersion of G-Actin

1962 • 38 citations

Preparation and polymerization properties of monomeric ADP-actin

1989 • 37 citations

Exposure of actin thiols by the removal of tightly held calcium ions.

1985 • 37 citations

Conformational changes in subdomain I of actin induced by proteolytic cleavage within the DNase I‐binding loop: energy transfer from tryptophan to AEDANS

1996 • 37 citations

Cross-Linking of Contractile Proteins from Skeletal Muscle by Treatment with Microbial Transglutaminase1

1992 • 36 citations

Domain Motion in Actin Observed by Fluorescence Resonance Energy Transfer

1994 • 36 citations

Role of ATP-bound divalent metal ion in the conformation and function of actin. Comparison of Mg-ATP, Ca-ATP, and metal ion-free ATP-actin.

1991 • 32 citations

The formation of actin oligomers studied by analytical ultracentrifugation.

1991 • 31 citations

Transglutaminase-Induced Cross-Linking between Subdomain 2 of G-Actin and the 636–642 Lysine-Rich Loop of Myosin Subfragment 1

1998 • 28 citations

Binding of nucleotide to cation-free G-actin

1971 • 25 citations

CHARACTERIZATION OF SKELETAL MUSCLE ACTIN LABELED WITH THE TRIPLET PROBE ERYTHROSIN‐5‐IODOACETAMIDE

1993 • 9 citations

Effects of Subtilisin Cleavage of Monomeric Actin on Its Nucleotide Binding

1996 • 7 citations