Liver endothelium mediates the uptake of iron-transferrin complex by hepatocytes

Chapter 4 Preparation of Isolated Rat Liver Cells

1976 • 5,335 citations

Intracellular site of asialoglycoprotein receptor-ligand uncoupling: Double-label immunoelectron microscopy during receptor-mediated endocytosis

1983 • 816 citations

Dansylcadaverine inhibits internalization of 125I-epidermal growth factor in BALB 3T3 cells.

1980 • 798 citations

Adsorption of horseradish peroxidase, ovomucoid and anti-immunoglobulin to colloidal gold for the indirect detection of concanavalin A, wheat germ agglutinin and goat anti-human immunoglobulin G on cell surfaces at the electron microscopic level: a new method, theory and application.

1977 • 608 citations

The galactose-specific recognition system of mammalian liver: The route of ligand internalization in rat hepatocytes

1980 • 484 citations

Receptor-Mediated Transport of Insulin Across Endothelial Cells

1985 • 462 citations

Biology of Endothelial Cells

1984 • 426 citations

In vivo and in vitro uptake and degradation of acetylated low density lipoprotein by rat liver endothelial, Kupffer, and parenchymal cells.

1983 • 396 citations

The specific binding of iron(III) and copper(II) to transferrin and conalbumin

1963 • 367 citations

Visualization of the binding, endocytosis, and transcytosis of low-density lipoprotein in the arterial endothelium in situ.

1983 • 349 citations

Subcellular membrane topology and turnover of a rat hepatic binding protein specific for asialoglycoproteins.

1979 • 259 citations

Solid state lactoperoxidase: A highly stable enzyme for simple, gentle iodination of proteins

1972 • 257 citations

Uptake of chemically modified low density lipoproteins in vivo is mediated by specific endothelial cells.

1985 • 219 citations

Distribution of Neuraminidase in Arthrobacter and Its Purification by Affinity Chromatography1

1977 • 151 citations

Characterization of the asialoglycoprotein receptor on isolated rat hepatocytes.

1980 • 149 citations

Glycoprotein catabolism in rat liver. Lysosomal digestion of iodinated asialo-fetuin

1975 • 145 citations

The Binding of Desialylated Glycoproteins by Plasma Membranes of Rat Liver

1972 • 138 citations

Clearance of acetyl low density lipoprotein by rat liver endothelial cells. Implications for hepatic cholesterol metabolism.

1984 • 125 citations

Turnover of the surface proteins and the receptor for serum asialoglycoproteins in primary cultures of rat hepatocytes.

1981 • 122 citations

The interaction of transferin with isolated hepatocytes

1980 • 119 citations

Transferrin receptors and the uptake and release of iron by isolated hepatocytes

1981 • 112 citations

Cell surface distribution and intracellular fate of asialoglycoproteins: a morphological and biochemical study of isolated rat hepatocytes and monolayer cultures

1982 • 99 citations

Processing of Insulin by Bovine Endothelial Cells in Culture: Internalization Without Degradation

1984 • 90 citations

Recycling of the asialoglycoprotein receptor in isolated rat hepatocytes. Dissociation of internalized ligand from receptor occurs in two kinetically and thermally distinguishable compartments.

1983 • 81 citations

Liver endothelium and not hepatocytes or Kupffer cells have transferrin receptors

1984 • 77 citations

Transendothelial transport (transcytosis) of iron—transferrin complex in the bone marrow

1984 • 71 citations

Morphological Characterization of Kupffer and Endothelial Cells of Rat Liver Isolated By Counterflow Elutriation

1978 • 68 citations

Some aspects of iron uptake by rat hepatocytes in suspension

1979 • 51 citations

Dual pathways for the uptake of rat asialotransferrin by rat hepatocytes.

1983 • 48 citations

Iron uptake from rat plasma transferrin by rat reticulocytes.

1978 • 48 citations

Identification of lectin-like substances recognizing galactosyl residues of glycoconjugates on the plasma membrane of marrow sinus endothelium

1985 • 45 citations

Ceruloplasmin receptors in liver cell suspensions are limited to the endothelium

1984 • 43 citations

Iron incorporation into isolated rat hepatocytes

1977 • 36 citations

Receptor distribution and the endothelial uptake of transcobalamin II in liver cell suspensions

1985 • 34 citations

Distribution of insulin receptors in liver cell suspensions using a minibead probe

1983 • 31 citations

Hepatic receptor for asialo-glycoproteins Ultrastructural demonstration of ligand-induced microaggregation of receptors

1981 • 30 citations

Biphasic uptake of iron-transferrin complex by L1210 murine leukemia cells and rat reticulocytes

1982 • 28 citations

Endocytosis and exocytosis of protein in capillary endothelium

1984 • 26 citations

Uptake of lactoferrin by the liver. III. Critical role of the protein moiety.

1984 • 25 citations

In vivo evidence for the functional heterogeneity of transferrin-bound iron. V. Isotransferrins: an explanation of the Fletcher-Huehns phenomenon in the rat.

1979 • 25 citations

The role of liver endothelium in the binding and uptake of ceruloplasmin: Studies with colloidal gold probe

1985 • 25 citations

Processing of insulin by bovine endothelial cells in culture. Internalization without degradation

1984 • 24 citations

Endothelial binding of transferrin in fractionated liver cell suspensions

1985 • 21 citations

Insulin uptake by rat liver endothelium studied in fractionated liver cell suspensions

1985 • 19 citations

Receptor distribution and the endothelial uptake of transcobalamin II in liver cell suspensions

1985 • 16 citations