Characterization of a Novel, Membrane-bound, 80-kDa Matrix-degrading Protease from Human Breast Cancer Cells

A matrix metalloproteinase expressed on the surface of invasive tumour cells

1994 • 2,561 citations

Amino acid analysis by reverse-phase high-performance liquid chromatography: Precolumn derivatization with phenylisothiocyanate

1984 • 1,616 citations

Mechanism Of Cell Surface Activation Of 72-kDa Type IV Collagenase

1995 • 1,576 citations

Localization of Matrix Metalloproteinase MMP-2 to the Surface of Invasive Cells by Interaction with Integrin αvβ3

1996 • 1,555 citations

Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis

1977 • 1,286 citations

Biology and biochemistry of proteinases in tumor invasion

1993 • 1,264 citations

Rat monoclonal antitubulin antibodies derived by using a new nonsecreting rat cell line.

1982 • 923 citations

Human 72-kilodalton type IV collagenase forms a complex with a tissue inhibitor of metalloproteases designated TIMP-2.

1989 • 594 citations

Association of increased basement membrane invasiveness with absence of estrogen receptor and expression of vimentin in human breast cancer cell lines

1992 • 530 citations

Identification of the Second Membrane-type Matrix Metalloproteinase (MT-MMP-2) Gene from a Human Placenta cDNA Library

1995 • 474 citations

Independent expression and cellular processing of Mr 72,000 type IV collagenase and interstitial collagenase in human tumorigenic cell lines.

1990 • 379 citations

Structural biochemistry and activation of matrix metalloproteases

1993 • 347 citations

Plasma membrane-dependent activation of the 72-kDa type IV collagenase is prevented by complex formation with TIMP-2

1993 • 338 citations

Molecular cloning of a novel membrane-type matrix metalloproteinase from a human breast carcinoma.

1996 • 330 citations

cDNA Sequence and mRNA Tissue Distribution of a Novel Human Matrix Metalloproteinase with a Potential Transmembrane Segment

1995 • 319 citations

cDNA Sequence and mRNA Tissue Distribution of a Novel Human Matrix Metalloproteinase with a Potential Transmembrane Segment

1995 • 244 citations

Intermolecular Autolytic Cleavage Can Contribute to the Activation of Progelatinase A by Cell Membranes

1995 • 242 citations

Membrane-type matrix metalloproteinase 1 is a gelatinolytic enzyme and is secreted in a complex with tissue inhibitor of metalloproteinases 2.

1996 • 232 citations

Destruction of extracellular matrices containing glycoproteins, elastin, and collagen by metastatic human tumor cells.

1980 • 221 citations

Metastatic tumor cells adhere preferentially to the extracellular matrix underlying vascular endothelial cells

1980 • 212 citations

Tissue inhibitor of metalloproteinases-2 inhibits the activation of 72 kDa progelatinase by fibroblast membranes

1991 • 201 citations

Expression of transformation-associated protease(s) that degrade fibronectin at cell contact sites.

1984 • 184 citations

Binding and localization of M(r) 72,000 matrix metalloproteinase at cell surface invadopodia.

1993 • 182 citations

Invasion of reconstituted basement membrane matrix by metastatic human tumor cells.

1986 • 160 citations

Tumor cell surface-associated binding site for the M(r) 72,000 type IV collagenase.

1992 • 153 citations

Urokinase plasminogen activator and urokinase plasminogen activator receptor in breast cancer

1995 • 150 citations

Cellular invasion into matrix beads: Localization of fa integrins and fibronectin to the invadopodia

1991 • 131 citations

Identification and characterization of a novel matrix-degrading protease from hormone-dependent human breast cancer cells.

1993 • 131 citations

Mechanism of interferon action: autoregulation of RNA-dependent P1/eIF-2 alpha protein kinase (PKR) expression in transfected mammalian cells.

1992 • 93 citations

Autolytic Activation of Recombinant Human 72 Kilodalton Type IV Collagenase

1995 • 79 citations

Progelatinase A activation during tumor cell invasion.

1994 • 79 citations

Amino acid analysis on polyvinylidene difluoride membranes

1989 • 77 citations

6 The urokinase/urokinase-receptor system and cancer invasion

1995 • 74 citations

Selective Degradation of Basement Membrane Macromolecules by Metastatic Melanoma Cells<xref ref-type="fn" rid="FN2">2</xref>

1984 • 63 citations

Metastatic mouse melanoma cells release collagen-gelatin degrading metalloproteinases as components of shed membrane vesicles

1987 • 51 citations

Chapter 5 Purification and Characterization of Dictyostelium discoideum Plasma Membranes

1987 • 43 citations

Degradation of endothelial basement membrane by human breast cancer cell lines.

1986 • 35 citations

Purification and characterization of a connective-tissue-degrading metalloproteinase from the cytosol of metastatic melanoma cells

1987 • 25 citations

Biosynthesis of reovirus-specified polypeptides: Effect of point mutation of the sequences flanking the 5′-proximal AUG initiator codons of the reovirus S1 and S4 genes on the efficiency of mRNA translation

1988 • 24 citations