Mapping the Ischaemic Penumbra with PET: Implications for Acute Stroke Treatment

Thresholds in cerebral ischemia - the ischemic penumbra.

1981 • 2,780 citations

Viability thresholds and the penumbra of focal ischemia

1994 • 1,358 citations

Thresholds of focal cerebral ischemia in awake monkeys

1981 • 1,144 citations

A Functional MRI Study of Subjects Recovered From Hemiparetic Stroke

1997 • 998 citations

Reversal of focal "misery-perfusion syndrome" by extra-intracranial arterial bypass in hemodynamic cerebral ischemia. A case study with 15O positron emission tomography.

1981 • 727 citations

Spontaneous neurological recovery after stroke and the fate of the ischemic penumbra

1996 • 507 citations

SERIAL OBSERVATIONS ON THE PATHOPHYSIOLOGY OF ACUTE STROKE

1983 • 424 citations

Progressive Derangement of Periinfarct Viable Tissue in Ischemic Stroke

1992 • 423 citations

Cerebral Blood Flow and Cerebral Metabolic Rate of Oxygen Requirements for Cerebral Function and Viability in Humans

1985 • 415 citations

Cerebral Oxygen Metabolism and Blood Flow in Human Cerebral Ischemic Infarction

1982 • 385 citations

Prolonged Persistence of Substantial Volumes of Potentially Viable Brain Tissue After Stroke

1996 • 318 citations

Noninvasive Tomographic Study of Cerebral Blood Flow and Oxygen Metabolism in vivo

1981 • 252 citations

Dynamic Penumbra Demonstrated by Sequential Multitracer PET after Middle Cerebral Artery Occlusion in Cats

1994 • 232 citations

The ischemic penumbra

1994 • 230 citations

PET imaging of cerebral perfusion and oxygen consumption in acute ischaemic stroke: relation to outcome

1993 • 219 citations

Role of the Nondominant Hemisphere and Undamaged Area During Word Repetition in Poststroke Aphasics

1996 • 190 citations

Positron Imaging in Ischemic Stroke Disease Using Compounds Labeled With Oxygen 15

1981 • 186 citations

The cerebral ischemic penumbra.

1987 • 175 citations

Use of PET Methods for Measurement of Cerebral Energy Metabolism and Hemodynamics in Cerebrovascular Disease

1989 • 166 citations

The functional anatomy of recovery from auditory agnosia

1995 • 154 citations

PET Study of Changes in Local Brain Hemodynamics and Oxygen Metabolism after Unilateral Middle Cerebral Artery Occlusion in Baboons

1993 • 137 citations

The effect of spontaneous reperfusion on metabolic function in early human cerebral infarcts

1987 • 134 citations

Early spontaneous hyperperfusion after stroke

1996 • 131 citations

Speech-induced cerebral metabolic activation reflects recovery from aphasia

1997 • 127 citations

Sequential Studies of Severely Hypometabolic Tissue Volumes After Permanent Middle Cerebral Artery Occlusion

1995 • 123 citations

Early Reperfusion in the Anesthetized Baboon Reduces Brain Damage Following Middle Cerebral Artery Occlusion

1997 • 99 citations

Relationships between High Oxygen Extraction Fraction in the Acute Stage and Final Infarction in Reversible Middle Cerebral Artery Occlusion: An Investigation in Anesthetized Baboons with Positron Emission Tomography

1996 • 95 citations

Transient Focal Ischemia in Subhuman Primates

1983 • 85 citations

Progressive impairment of brain oxidative metabolism reversed by reperfusion following middle cerebral artery occlusion in anaesthetized baboons

1997 • 57 citations

Pathophysiology of Brain Ischemia as It Relates to the Therapy of Acute Ischemic Stroke

1990 • 49 citations

Thresholds of cerebral ischemia

1977 • 28 citations

Human Hemispheric Infarction Studied by Positron Emission Tomography and the 15 0 Continous Inhalation Technique

1980 • 17 citations