Application of polyethylene glycol-modified enzymes in biotechnological processes: organic solvent-soluble enzymes

Chemical Modification of Proteins

2012 • 1,097 citations

Chemical Approaches to the Properties of Active Sites of Enzymes

1969 • 236 citations

Ester synthesis catalyzed by polyethylene glycol-modified lipase in benzene

1984 • 152 citations

A chemical modification to make horseradish peroxidase soluble and active in benzene

1984 • 128 citations

Chymotrypsin modified with polyethylene glycol catalyzes peptide synthesis reaction in benzene

1984 • 94 citations

Polymerization of 10-hydroxydecanoic acid in benzene with polyethylene glycol-modified lipase

1985 • 94 citations

Engineering physicochemical and biological properties of proteins by chemical modification

1986 • 86 citations

Chemical reactions by polyethylene glycol-modified enzymes in chlorinated hydrocarbons

1985 • 84 citations

Polyethylene glycol-modified enzymes trap water on their surface and exert enzymic activity in organic solvents

1984 • 81 citations

Polyethylene glycol-modified catalase exhibits unexpectedly high activity in benzene

1984 • 79 citations

MODIFICATION OF E. COLI ASPARAGINASE WITH 2,4-BIS(O-METHOXYPOLYETHYLENE GLYCOL)-6-CHLORO-S-TRIAZINE(ACTIVATED PEG₂); DISAPPEARANCE OF BINDING ABILITY TOWARDS ANTI-SERUM AND RETENTION OF ENZYMIC ACTIVITY

1980 • 78 citations

Modified lipase having high stability and various enzymic activities in benzene, and its re-use by recovering from benzene solution

1984 • 65 citations

Modification of batroxobin with activated polyethylene glycol: Reduction of binding ability towards anti-batroxobin antibody and retention of defibrinogenation activity in circulation of preimmunized dogs

1983 • 45 citations

Ester-exchange catalyzed by lipase modified with polyethylene glycol

1985 • 45 citations

Modified Lipoprotein Lipase Catalyzes Ester Synthesis in Benzene

1984 • 39 citations

Improved Modification of Yeast Uricase with Polyethylene Glycol, Accompanied with Nonimmunoreactivity towards Anti- Uricase Serum and High Enzymic Activity

1981 • 36 citations

A DIRECT METHOD FOR α-METHYLENEBUTYROLACTONE SYNTHESIS USING HOMOALLYL ALCOHOLS

1978 • 35 citations

Ester-exchange reaction between triglycerides with polyethylene glycol-modified lipase

1986 • 31 citations

Suppression of IgE Antibody Response by the Fatty Acid-Modified Antigen

1981 • 17 citations

Suppression of IgE Antibody Response against Ovalbumin by the Chemical Conjugate of Ovalbumin with a Polyaspartic Acid Derivative

1985 • 14 citations