Amplification, mutation and selection of catalytic RNA

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Self-splicing RNA: Autoexcision and autocyclization of the ribosomal RNA intervening sequence of tetrahymena

1982 • 2,241 citations

Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates

1987 • 2,098 citations

Depurination-induced infidelity of DNA synthesis with purified DNA replication proteins in vitro

1983 • 137 citations

4 Bacteriophage DNA-Dependent RNA Polymerases

1982 • 82 citations

Segment-specific mutagenesis of the regulatory region in the Escherichia coli galactose operon: isolation of mutations reducing the initiation of transcription and translation

1983 • 70 citations

Catalysis of splicing-related reactions between dinucleotides by a ribozyme

1987 • 56 citations

Reverse transcriptase and its associated ribonuclease H: interplay of two enzyme activities controls the yield of single-stranded cDNA

1983 • 52 citations

Nucleotide sequence of a second glutamine tRNA gene in wheat mitochondrial DNA

1989 • 25 citations

Structure of the catalytic core of the Tetrahymena ribozyme as indicated by reactive abbreviated forms of the molecule

1987 • 22 citations

On the fidelity of DNA replication. Specificity of nucleotide substitution by intercalating agents.

1983 • 13 citations