Identification of the developmental marker, JB3-antigen, as fibrillin-2 and its de novo organization into embryonic microfibrous arrays

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A series of normal stages in the development of the chick embryo

1951 • 12,226 citations

Marfan syndrome caused by a recurrent de novo missense mutation in the fibrillin gene

1991 • 2,004 citations

Fibrillin, a new 350-kD glycoprotein, is a component of extracellular microfibrils.

1986 • 1,129 citations

Early stages of chick somite development

1995 • 781 citations

Linkage of Marfan syndrome and a phenotypically related disorder to two different fibrillin genes

1991 • 666 citations

Extracellular matrix 4: The elastic fiber

1993 • 598 citations

TGF-β1 binding protein: A component of the large latent complex of TGF-β1 with multiple repeat sequences

1990 • 447 citations

Solution Structure of a Pair of Calcium-Binding Epidermal Growth Factor-like Domains: Implications for the Marfan Syndrome and Other Genetic Disorders

1996 • 437 citations

Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matrices

1994 • 386 citations

Partial sequence of a candidate gene for the Marfan syndrome

1991 • 370 citations

Genomic organization of the sequence coding for fibrillin, the defective gene product in Marfan syndrome

1993 • 356 citations

Genomic organization of the sequence coding for fibrillin, the defective gene product in Marfan syndrome

1993 • 312 citations

Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils.

1995 • 307 citations

Fibrillin–2 (FBN2) mutations result in the Marfan–like disorder, congenital contractural arachnodactyly

1995 • 283 citations

Purification and partial characterization of fibrillin, a cysteine-rich structural component of connective tissue microfibrils

1991 • 276 citations

Elastin-Associated Microfibrils and Microfibrillar Proteins

1983 • 266 citations

Genetic Linkage of the Marfan Syndrome, Ectopia Lentis, and Congenital Contractural Arachnodactyly to the Fibrillin Genes on Chromosomes 15 and 5

1992 • 262 citations

Fibrillin Binds Calcium and Is Coded by cDNAs That Reveal a Multidomain Structure and Alternatively Spliced Exons at the 5′ End

1993 • 259 citations

Microfibrils: Fine filamentous components of the tissue space

1962 • 234 citations

Extraction of extendable beaded structures and their identification as fibrillin-containing extracellular matrix microfibrils.

1991 • 205 citations

Development of the Aortic Vessel Wall as Defined by Vascular Smooth Muscle and Extracellular Matrix Markers

1996 • 196 citations

Secretion of collagen by embryonic neuroepithelium at the time of spinal cord-somite interaction

1971 • 188 citations

Bovine Latent Transforming Growth Factor β1-Binding Protein 2: Molecular Cloning, Identification of Tissue Isoforms, and Immunolocalization to Elastin-Associated Microfibrils

1995 • 186 citations

Congenital contractural arachnodactyly. A heritable disorder of connective tissue.

1971 • 167 citations

Marfan phenotype variability in a family segregating a missense mutation in the epidermal growth factor-like motif of the fibrillin gene.

1992 • 151 citations

Elastic Fiber Structure and Assembly

1994 • 148 citations

Epithelial-Mesenchymal Transformations in Early Avian Heart Development

1996 • 139 citations

Congenital Contractural Arachnodactyly

1971 • 137 citations

The Elastic Fiber

1991 • 133 citations

Clustering of fibrillin (FBN1) missense mutations in Marfan syndrome patients at cysteine residues in EGF-like domains

1992 • 132 citations

Antibodies to β₁‐integrins cause alterations of aortic vasculogenesis, in vivo

1992 • 126 citations

Complementary DNA cloning establishes microfibril-associated glycoprotein (MAGP) to be a discrete component of the elastin-associated microfibrils.

1991 • 126 citations

Formation and Early Morphogenesis of Endocardial Endothelial Precursor Cells and the Role of Endoderm

1996 • 126 citations

Cardiac Endothelial Heterogeneity Defines Valvular Development as Demonstrated by the Diverse Expression of JB3, an Antigen of the Endocardial Cushion Tissue

1994 • 125 citations

Two mutations in Marfan syndrome resulting in truncated fibrillin polypeptides.

1992 • 117 citations

Retinoic Acid Directs Cardiac Laterality and the Expression of Early Markers of Precardiac Asymmetry

1997 • 92 citations

Fibrillin-1 and Fibrillin-2 Show Temporal and Tissue-Specific Regulation of Expression in Developing Elastic Tissues

1995 • 89 citations

Familial occurrence of typical and severe lethal congenital contractural arachnodactyly caused by missplicing of exon 34 of fibrillin-2.

1996 • 78 citations

Characterization of an associated microfibril protein through recombinant DNA techniques.

1992 • 76 citations

Immunolocalization of microfibril and microfibril-associated proteins in the subendothelial matrix of the developing mouse aorta

1994 • 76 citations

Origin and propagation of elastogenesis in the developing cardiovascular system

1988 • 70 citations

The fibrillin‐marfan syndrome connection

1993 • 53 citations

Perturbation of β1 integrin-mediated adhesions results in altered somite cell shape and behavior

1992 • 52 citations

Fibrillin delineates the primary axis of the early avian embryo

1993 • 49 citations

Molecular cloning of the microfibrillar protein MFAP3 and assignment of the gene to human chromosome 5q32–q33.2

1995 • 47 citations

Primary Structure and Developmental Expression of Fbn-1, the Mouse Fibrillin Gene

1995 • 42 citations

Isolation and Characterization of a 36-kDa Microfibril-Associated Glycoprotein by the Newly Synthesized Isoquinolinesulfonamide Affinity Chromatography

1994 • 41 citations

Integrins play an essential role in somite adhesion to the embryonic axis

1991 • 36 citations

Distribution of connective tissue proteins during development and neovascularization of the epicardium

1996 • 36 citations

Tropoelastin gene expression in the developing vascular system of the chicken: an in situ hybridization study

1993 • 28 citations

The clinical spectrum of congenital contractural arachnodactyly

1974 • 26 citations

Cardiac anomalies complicating congenital contractural arachnodactyly.

1991 • 23 citations

Fibrillin genes map to regions of conserved mouse/human syntenyon mouse chromosomes 2 and 18

1993 • 22 citations

Research Perspectives in Heritable Disorders of Connective Tissue

1992 • 11 citations