Induction of drug metabolism in man after rifampicin treatment measured by increased hexobarbital and tolbutamide clearance

Clearance concepts in pharmacokinetics

1973 • 741 citations

Lidocaine Pharmacokinetics in Advanced Heart Failure, Liver Disease, and Renal Failure in Humans

1973 • 504 citations

The liver: quantitative aspects of structure and function

1973 • 369 citations

FACTORS AFFECTING DRUG METABOLISM

1971 • 342 citations

Determination of drug metabolizing enzymes in needle biopsies of human liver

1972 • 332 citations

Assessment of Pharmacokinetic Constants from Postinfusion Blood Curves Obtained after I.V. Infusion

1970 • 317 citations

CHANGES IN CORTISOL METABOLISM FOLLOWING RIFAMPICIN THERAPY

1974 • 211 citations

Hepatic Circulation in Cirrhosis of the Liver

1952 • 165 citations

The Metabolic Fate of Tolbutamide in Man and in the Rat

1966 • 137 citations

Increased Clearance of Antipyrine and d-Propranolol after Phenobarbital Treatment in the Monkey

1974 • 134 citations

Kinetics of rifampicin and isoniazid administered alone and in combination to normal subjects and patients with liver disease

1972 • 119 citations

RIFAMPICIN HEPATITIS

1974 • 118 citations

�ber eine M�glichkeit zur colorimetrischen Bestimmung von N-(4-Methyl-benzolsulfonyl)-N?-butyl-Harnstoff in Serum

1957 • 94 citations

Changes of the smooth endoplasmic reticulum induced by rifampicin in human and guinea-pig hepatocytes

1971 • 92 citations

Wirkung von Rifampicin auf den Menstruationszyklus und die Östrogenausscheidung bei Einnahme oraler Kontrazeptiva

1973 • 90 citations

Induction of the Unspecific Microsomal Hydroxylase in the Human Liver

2015 • 75 citations

Serum concentration and half-life of rifampicin after simultaneous oral administration of aminosalicylic acid or isoniazid

1974 • 49 citations

Metabolic Fate of Hexobarbital (HBj

1972 • 49 citations

Rapid and sensitive gas chromatographic determination of hexobarbital in plasma of man using a nitrogen detector

1974 • 46 citations

Effect of route of administration on drug disposition

1973 • 44 citations

Pharmacokinetics of hexobarbital in man after intravenous infusion

1975 • 42 citations

The metabolic fate of 5-(1-cyclohexen-1-yl)-1, 5-dimethyl barbituric acid (hexobarbital, evipal) and of 5-(1-cyclohexen-1-yl)-5-methyl barbituric acid ("nor-evipal").

1953 • 34 citations

[Rimactan (rifampicin) and anticoagulant therapy].

1970 • 32 citations

Half-Life of Rifampicin after Repeated Administration of Different Doses in Humans

1972 • 26 citations

Significance of Pharmacokinetics for Drug Design and the Planning of Dosage Regimens

1971 • 21 citations

Determination of carboxytolbutamide in urine

1960 • 20 citations

Rifampicin desacetylation in the human organism.

1969 • 19 citations

Kinetic studies on rifampicin

1972 • 19 citations

The stimulant effect of drugs on indocyanine green clearance by the liver

1972 • 16 citations

[Pharmacokinetics of glymidine (glycodiazine) and tolbutamide in acute and chronic liver diseases].

1973 • 13 citations

[Binding of sulfonamides to protein. 6. Determination of protein binding of sulfonamides by means of ultracentrifuge and gel filtration].

1965 • 12 citations

Serum concentration of rifampin after oral administration

1974 • 5 citations

Detection of Hydroxyl Derivatives from the Urine of Men administered Ethylhexabital and Methylhexabital by Buffered Paper Chromatography.

1957 • 4 citations

[Comparative findings on the metabolism, excretion & identification of sedatives in the barbiturate series].

1959 • 3 citations

Pharmacokinetics of hypnotic drugs: studies on the pharmacokinetics and biopharmaceutics of barbiturates and chloral hydrate in man

1974 • 3 citations

[Hypoglycemia by means of an oral antidiabetic & the effect of N-(4-methyl-benzolsulfonyl)-N'-butylurea in blood in relation to liver function].

1958 • 1 citations