Abnormal expression of the E2 component of the pyruvate dehydrogenase complex on the luminal surface of biliary epithelium occurs before major histocompatibility complex class II and BB1/B7 expression
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References (32)
Primary Biliary Cirrhosis
1987 • 1,981 citations
The use of avidin-biotin interaction in immunoenzymatic techniques.
1979 • 1,734 citations
B70 antigen is a second ligand for CTLA-4 and CD28
1993 • 907 citations
ABERRANT EXPRESSION OF HLA-DR ANTIGEN ON THYROCYTES IN GRAVES' DISEASE: RELEVANCE FOR AUTOIMMUNITY
1983 • 710 citations
Suppression of endogenous avidin-binding activity in tissues and its relevance to biotin-avidin detection systems.
1981 • 545 citations
Liver Biopsy Interpretation
1959 • 518 citations
ABERRANT EXPRESSION OF HLA-DR ANTIGENS ON BILEDUCT EPITHELIUM IN PRIMARY BILIARY CIRRHOSIS: RELEVANCE TO PATHOGENESIS
1984 • 496 citations
B7, a new member of the Ig superfamily with unique expression on activated and neoplastic B cells.
1989 • 487 citations
Intracellular neutralization of virus by immunoglobulin A antibodies.
1992 • 438 citations
BIRTH CONTROL FOR PROBLEM PARENTS
1964 • 381 citations
A three-tiered view of the role of IgA in mucosal defense
1993 • 374 citations
B lymphoblast antigen (BB-1) expressed on Epstein-Barr virus-activated B cell blasts, B lymphoblastoid cell lines, and Burkitt's lymphomas.
1982 • 297 citations
The autoepitope of the 74-kD mitochondrial autoantigen of primary biliary cirrhosis corresponds to the functional site of dihydrolipoamide acetyltransferase.
1988 • 283 citations
Identification and analysis of the major M2 autoantigens in primary biliary cirrhosis.
1988 • 277 citations
Functional expression of B7/BB1 on activated T lymphocytes.
1993 • 271 citations
Aberrant expression of Class II major histocompatibility complex molecules by B cells and hyperexpression of Class I major histocompatibility complex molecules by insulin containing islets in Type 1 (insulin-dependent) diabetes mellitus
1987 • 243 citations
Histometric and serial section observations of the intrahepatic bile ducts in primary biliary cirrhosis
1979 • 213 citations
The role of cell division in the induction of clonal anergy
1992 • 203 citations
Comparison of the Clinicopathologic Features of Primary Sclerosing Chol-angitis and Primary Biliary Cirrhosis
1985 • 196 citations
Molecular mimicry in primary biliary cirrhosis. Evidence for biliary epithelial expression of a molecule cross-reactive with pyruvate dehydrogenase complex-E2.
1993 • 185 citations
Antimitochondrial autoantibodies in primary biliary cirrhosis recognize cross-reactive epitope(s) on protein X and dihydrolipoamide acetyltransferase of pyruvate dehydrogenase complex
1989 • 125 citations
Primary biliary cirrhosis. Inhibition of pyruvate dehydrogenase complex activity by autoantibodies specific for E1 alpha, a non-lipoic acid containing mitochondrial enzyme.
1990 • 107 citations
A monoclonal antibody that detects HLA-D region antigen in routinely fixed, wax embedded sections of normal and neoplastic lymphoid tissues.
1985 • 90 citations
Liver Biopsy Interpretation
1980 • 81 citations
Comparative epitope mapping of murine monoclonal and human autoantibodies to human PDH-E2, the major mitochondrial autoantigen of primary biliary cirrhosis.
1990 • 80 citations
Expression of HLA-DR antigens on interlobular bile ducts in primary biliary cirrhosis and other hepatobiliary diseases: An immunohistochemical study
1991 • 52 citations
The Role of Genetically‐Determined Primary Alterations of the Target Organ in the Development of Spontaneous Autoimmune Thyroiditis in Obese Strain (OS) Chickens
1986 • 46 citations
Heterogeneity of Combinatorial Human Autoantibodies Against Pdc–E2 and Biliary Epithelial Cells in Patients With Primary Biliary Cirrhosis
1994 • 41 citations
Human combinatorial autoantibodies and mouse monoclonal antibodies to PDC-E2 produce abnormal apical staining of salivary glands in patients with coexistent primary biliary cirrhosis and Sjogren's syndrome
1994 • 41 citations
Diseases of the liver and biliary tract : standardization of nomenclature, diagnostic criteria, and prognosis
1994 • 27 citations
Diseases of the Liver and Biliary Tract: Standardization of Nomenclature, Diagnostic Criteria, and Prognosis
1995 • 23 citations
Secretory Immunoglobulin A in Hepatobiliary Diseases
1991 • 13 citations