Brain-derived neurotrophic factor modulates GAP-43 but not t?1 expression in injured retinal ganglion cells of adult rats

The Trk family of neurotrophin receptors

1994 • 1,271 citations

Axonal Growth-Associated Proteins

1989 • 1,118 citations

Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats

1994 • 817 citations

Effects of ocular injury and administration ofbrain-derived neurotrophic factor on survival and regrowth of axotomized retinalganglion cells.

1994 • 727 citations

Overexpression of the neural growth-associated protein GAP-43 induces nerve sprouting in the adult nervous system of transgenic mice

1995 • 612 citations

Axonally transported proteins associated with axon growth in rabbit central and peripheral nervous systems

1981 • 583 citations

Effects of brain-derived neurotrophic factor on optic axon branching and remodelling in vivo

1995 • 583 citations

Primary structure and biological activity of a novel human neurotrophic factor

1990 • 553 citations

Intravitreal injections of neurotrophic factors support the survival of axotomized retinal ganglion cells in adult rats in vivo

1993 • 543 citations

Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells

1993 • 525 citations

Brain-derived neurotrophic factor supports the survival of cultured rat retinal ganglion cells

1986 • 519 citations

Rapid and protracted phases of retinal ganglion cell loss follow axotomy in the optic nerve of adult rats

1993 • 458 citations

Evidence for an amacrine cell system in the ganglion cell layer of the rat retina

1981 • 394 citations

Neuronal pathfinding is abnormal in mice lacking the neuronal growth cone protein GAP-43

1995 • 384 citations

Aminoalkylsilane-treated glass slides as support forin situ hybridization of keratin cDNAs to frozen tissue sections under varying fixation and pretreatment conditions

1986 • 383 citations

Primary structure and transcriptional regulation of GAP-43, a protein associated with nerve growth

1987 • 358 citations

Expression of the growth-associated protein GAP-43 in adult rat retinal ganglion cells following axon injury

1991 • 314 citations

Retrograde axonal transport of LIF is increased by peripheral nerve injury: Correlation with increased LIF expression in distal nerve

1994 • 268 citations

Increased transport of 44,000- to 49,000-dalton acidic proteins during regeneration of the goldfish optic nerve: a two-dimensional gel analysis

1983 • 220 citations

Survival and Axonal Elongation of Adult Rat Retinal Ganglion Cells

1989 • 210 citations

Cells that Express Brain‐Derived Neurotrophic Factor mRNA in the Developing Postnatal Rat Brain

1991 • 208 citations

Isotypes of alpha-tubulin are differentially regulated during neuronal maturation.

1987 • 207 citations

Brain-Derived Neurotrophic Factor and Neurotrophin-4/5 Stimulate Growth of Axonal Branches from Regenerating Retinal Ganglion Cells

1996 • 206 citations

The T alpha 1 alpha-tubulin promoter specifies gene expression as a function of neuronal growth and regeneration in transgenic mice

1994 • 196 citations

Rapid induction of the major embryonic alpha-tubulin mRNA, T alpha 1, during nerve regeneration in adult rats.

1989 • 196 citations

Absence of persistent spreading, branching, and adhesion in GAP-43-depleted growth cones.

1995 • 183 citations

Elevated synthesis of an axonally transported protein correlates with axon outgrowth in normal and injured pyramidal tracts

1986 • 182 citations

Dual regulation of GAP-43 gene expression by nerve growth factor and glucocorticoids.

1988 • 181 citations

Rapid induction of the major embryonic alpha-tubulin mRNA, T alpha 1, during nerve regeneration in adult rats

1989 • 179 citations

Gap‐43 immunoreactivity and axon regeneration in retinal ganglion cells of the rat

1994 • 171 citations

Neurotrophin‐4/5 (NT‐4/5) increases adult rat retinal ganglion cell survival and neurite outgrowth in vitro

1994 • 169 citations

The survival of chick retinal ganglion cells in response to brain-derived neurotrophic factor depends on their embryonic age

1989 • 154 citations

Different forms of the neurotrophin receptor TrkB mRNA predominate in rat retina and optic nerve

1993 • 151 citations

Neurotrophin signalling

1994 • 142 citations

Selective enhancement of axonal branching of cultured dentate gyrus neurons by neurotrophic factors

1995 • 110 citations

The effects of a lesion or a peripheral nerve graft on GAP-43 upregulation in the adult rat brain: an in situ hybridization and immunocytochemical study

1995 • 104 citations

Concentration-dependent regulation of neuronal gene expression by nerve growth factor

1992 • 94 citations

Immunohistochemical localization of basic fibroblast growth factor in mature and developing retinas of normal and RCS rats

1992 • 70 citations

Neurite outgrowth and GAP‐43 mRNA expression in cultured adult rat dorsal root ganglion neurons: Effects of NGF or prior peripheral axotomy

1994 • 65 citations

Nerve growth factor stimulation of GAP-43 phosphorylation in intact isolated growth cones

1991 • 64 citations

Nerve growth factor and neurotrophin-3 enhance neurite outgrowth and up-regulate the levels of messenger RNA for growth-associated protein GAP-43 and Tα1 α-tubulin in cultured adult rat sensory neurones

1995 • 53 citations

Developmentally regulated rat brain mRNAs: molecular and anatomical characterization.

1987 • 53 citations

Evidence That the Loss of Homeostatic Signals Induces Regeneration-Associated Alterations in Neuronal Gene Expression

1993 • 50 citations

Developmental study of the expression of B50/GAP‐43 in rat retina

1993 • 43 citations

Activity-dependent sharpening of the regenerating retinotectal projection in goldfish: relationship to the expression of growth-associated proteins

1987 • 42 citations

Anti-NGF treatment blocks the upregulation of NGF receptor mRNA expression associated with collateral sprouting of rat dorsal root ganglion neurons

1995 • 38 citations

Influence of spinal cord transection on the presence and axonal transport of CGRP‐, chromogranin A‐, VIP‐, synapsin I‐, and synaptophysin‐like immunoreactivities in rat motor nerve

1992 • 38 citations

Developing Rat Retinal Ganglion Cells Express the Functional NGF Receptor p140trkA

1993 • 37 citations

Electrophoretic Analysis of Axonally Transported Proteins in Toad Retinal Ganglion Cells

1981 • 33 citations

Neurotrophin‐3 receptors in the developing chicken retina

1993 • 28 citations

Gene regulation of trkB and trkC in the chick retina by light/darkness exposure.

1994 • 26 citations

NGF-Induced Stabilization of Gap-43 mRNA Is Mediated by Both 3′ Untranslated Region and a Segment Encoding the Carboxy-Terminus Peptide

1994 • 20 citations

Effect of target removal on goldfish optic nerve regeneration: analysis of fast axonally transported proteins.

1990 • 18 citations

Effect of target removal on goldfish optic nerve regeneration: analysis of fast axonally transported proteins

1990 • 16 citations

Factors influencing regeneration of retinal ganglion cell axons in adult mammals

1989 • 11 citations