Differentiation between High- and Low-Grade Astrocytoma Using a Human Recombinant Antibody to the Extra Domain-B of Fibronectin

Applied Regression Analysis and Other Multivariable Methods

1989 • 8,685 citations

Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis

1996 • 6,878 citations

Rapid generation of functional human IgG antibodies derived from Fab-on-phage display libraries.

2004 • 2,484 citations

The WHO Classification of Tumors of the Nervous System

2002 • 1,931 citations

Pathology and genetics of tumours of the nervous system.

2000 • 1,374 citations

Design and Use of a Phage Display Library

1998 • 423 citations

Selective targeting of tumoral vasculature: Comparison of different formats of an antibody (L19) to the ED‐B domain of fibronectin

2002 • 346 citations

A tumor-associated fibronectin isoform generated by alternative splicing of messenger RNA precursors.

1989 • 339 citations

Transformed human cells produce a new fibronectin isoform by preferential alternative splicing of a previously unobserved exon.

1987 • 334 citations

The fibronectin isoform containing the ed‐b oncofetal domain: A marker of angiogenesis

1994 • 306 citations

Enhancement of the antitumor properties of interleukin-2 by its targeted delivery to the tumor blood vessel extracellular matrix

2002 • 290 citations

Targeting by affinity–matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform

1997 • 289 citations

Immunoscintigraphic detection of the ED-B domain of fibronectin, a marker of angiogenesis, in patients with cancer.

2003 • 282 citations

Enhancement of the antitumor activity of interleukin-12 by targeted delivery to neovasculature

2002 • 258 citations

Comprehensive assessment of hemorrhage risks and outcomes after stereotactic brain biopsy

2001 • 234 citations

Stromal Involvement In Malignant Growth

1988 • 225 citations

Targeted delivery of tissue factor to the ED-B domain of fibronectin, a marker of angiogenesis, mediates the infarction of solid tumors in mice.

2001 • 223 citations

A High-Affinity Human Antibody That Targets Tumoral Blood Vessels

1999 • 209 citations

Increased binding affinity and valence of recombinant antibody fragments lead to improved targeting of tumoral angiogenesis.

1999 • 208 citations

Distribution of oncofetal fibronectin isoforms in normal, hyperplastic and neoplastic human breast tissues

1994 • 154 citations

Phage antibodies with pan-species recognition of the oncofoetal angiogenesis marker fibronectin ED-B domain

1996 • 151 citations

Transforming growth factor‐β regulates the splicing pattern of fibronectin messenger RNA precursor

1990 • 129 citations

The inclusion of the type III repeat ED-B in the fibronectin molecule generates conformational modifications that unmask a cryptic sequence.

1992 • 127 citations

Molecular variants of fibronectin and laminin: structure, physiological occurrence and histopathological aspects

1996 • 124 citations

Identification of a Glioblastoma-Associated Tenascin-C Isoform by a High Affinity Recombinant Antibody

1999 • 116 citations

Selective targeting and photocoagulation of ocular angiogenesis mediated by a phage-derived human antibody fragment

1999 • 115 citations

Observer reliability in histological grading of astrocytoma stereotactic biopsies

1996 • 108 citations

Extracellular matrix proteins in colorectal carcinomas. Expression of tenascin and fibronectin isoforms.

1995 • 81 citations

The Alternative Splicing Pattern of the Tenascin-C Pre-mRNA Is Controlled by the Extracellular pH

1995 • 80 citations

Lack of specificity of endoglin expression for tumor blood vessels

2001 • 60 citations

Interstitial Collagenase and the ED-B Oncofetal Domain of Fibronectin Are Markers of Angiogenesis in Human Skin Tumors

1998 • 21 citations