Characterization of a cDNA encoding the heparin and collagen binding domains of human thrombospondin.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Studies on transformation of Escherichia coli with plasmids

1983 • 11,179 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

A simple and very efficient method for generating cDNA libraries

1983 • 4,606 citations

Rapid and Sensitive Protein Similarity Searches

1985 • 4,091 citations

Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

1979 • 3,525 citations

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

1984 • 3,334 citations

Construction of improved M13 vectors using oligodeoxynucleotide-directed mutagenesis

1983 • 2,609 citations

Plasmid screening at high colony density

1980 • 1,100 citations

Polymorphism of DNA sequence adjacent to human beta-globin structural gene: relationship to sickle mutation.

1978 • 804 citations

Primary structure of human fibronectin: differential splicing may generate at least 10 polypeptides from a single gene.

1985 • 659 citations

Isolation and characterization of a high molecular weight glycoprotein from human blood platelets.

1978 • 428 citations

Complete amino acid sequence of human vitronectin deduced from cDNA. Similarity of cell attachment sites in vitronectin and fibronectin.

1985 • 418 citations

Ligation of EcoRI endonuclease-generated DNA fragments into linear and circular structures

1975 • 411 citations

Purification of glycoproteins IIb and III from human platelet plasma membranes and characterization of a calcium-dependent glycoprotein IIb-III complex.

1982 • 337 citations

Synthesis and secretion of thrombospondin by cultured human endothelial cells.

1982 • 311 citations

Cloning and characterization of two cDNAs coding for human von Willebrand factor.

1985 • 302 citations

Thrombospondin: synthesis and secretion by cells in culture.

1982 • 259 citations

Role of thrombospondin in platelet aggregation.

1984 • 247 citations

Platelet-derived growth factor and heparin-like glycosaminoglycans regulate thrombospondin synthesis and deposition in the matrix by smooth muscle cells.

1985 • 232 citations

Interactions of thrombospondin with extracellular matrix proteins: selective binding to type V collagen.

1984 • 202 citations

Complex formation of platelet thrombospondin with fibrinogen.

1982 • 195 citations

The platelet glycoprotein thrombospondin binds specifically to sulfated glycolipids.

1985 • 191 citations

Isolation and characterization of a heparin-binding domain from the amino terminus of platelet thrombospondin.

1984 • 181 citations

An improved procedure for utilizing terminal transferase to add homopolymers to the 3′ termini of DNA

1981 • 176 citations

Laminin binds specifically to sulfated glycolipids.

1985 • 158 citations

A monoclonal antibody against human thrombospondin inhibits platelet aggregation.

1985 • 152 citations

Granular pneumocytes in primary culture secrete several major components of the extracellular matrix

1983 • 126 citations

Thrombospondin interactions with fibronectin and fibrinogen. Mutual inhibition in binding

1984 • 116 citations

Platelet thrombospondin forms a trimolecular complex with plasminogen and histidine-rich glycoprotein.

1985 • 113 citations

Regulation of thrombospondin secretion by cells in culture

1984 • 112 citations

Monoclonal antibodies that recognize calcium-dependent structures of human thrombospondin. Characterization and mapping of their epitopes.

1986 • 111 citations

Mapping of epitopes for monoclonal antibodies against human platelet thrombospondin with electron microscopy and high sensitivity amino acid sequencing.

1985 • 109 citations

The release of heparin binding peptides from platelet thrombospondin by proteolytic action of thrombin, plasmin and trypsin

1981 • 108 citations

Structure of thrombospondin.

1984 • 74 citations

Synthesis of full-length DNA copies of avian myeloblastosis virus RNA in high yields.

1977 • 68 citations

A collagenolytic serine protease with trypsin-like specificity from the fiddler crab Uca pugilator

1983 • 63 citations

Antibodies against a 23Kd heparin binding fragment of thrombospondin inhibit platelet aggregation

1984 • 53 citations

Isolation of the fibrinogen-binding region of platelet thrombospondin

1984 • 49 citations

Location and partial characterization of the heparin-binding fragment of platelet thrombospondin

1984 • 46 citations

Localization of the hemagglutinating activity of platelet thrombospondin to a 140,000-dalton thermolytic fragment

1984 • 45 citations

Characterization of the platelet agglutinating activity of thrombospondin

1985 • 22 citations