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The Clinical Pharmacology of Lidocaine as an Antiarrhythymic Drug

Data up to Jan 2025

Published1974
Citations263
References54

Total Citations Per Year

Abstract

References (54)

The Coronary Care Unit

1967 • 544 citations

Lidocaine Pharmacokinetics in Advanced Heart Failure, Liver Disease, and Renal Failure in Humans

1973 • 504 citations

The Coronary-Care Unit

1968 • 470 citations

Effect of Lidocaine on Ventricular Arrhythmias in Patients with Coronary Heart Disease

1967 • 380 citations

COMPARISON OF TOXICITY OF INTRAVENOUSLY GIVEN LOCAL ANESTHETIC AGENTS IN MAN

1960 • 277 citations

Effect of lidocaine on the electrophysiological properties of ventricular muscle and Purkinje fibers

1970 • 269 citations

Interrelationships of Hepatic Blood Flow, Cardiac Output, and Blood Levels of Lidocaine in Man

1971 • 267 citations

Pharmacokinetics of lidocaine in man

1971 • 226 citations

Concentrations of lignocaine in the blood after intravenous, intramuscular epidural and endotracheal administration

1961 • 218 citations

DISPOSITION KINETICS OF LIDOCAINE IN NORMAL SUBJECTS*

1971 • 189 citations

LIGNOCAINE IN THE MANAGEMENT OF ARRHYTHMIAS AFTER ACUTE MYOCARDIAL INFARCTION

1968 • 178 citations

Electrophysiological Actions of Lidocaine on Canine Ventricular Muscle and Purkinje Fibers

1969 • 161 citations

The Use of procaine amide and lidocaine in the treatment of cardiac arrhythmias

1969 • 135 citations

Cardiac and peripheral vascular effects of lidocaine and procainamide

1965 • 125 citations

The convulsant potency of lidocaine and its N-dealkylated metabolites.

1973 • 114 citations

LIGNOCAINE GIVEN PROPHYLACTICALLY TO PATIENTS WITH ACUTE MYOCARDIAL INFARCTION

1971 • 114 citations

The influence of heart failure, liver disease, and renal failure on the disposition of lidocaine in man

1971 • 114 citations

VENTRICULAR FIBRILLATION PRECIPITATED BY CARDIAC CATHETERIZATION

1950 • 112 citations

The reduction of lidocaine clearance by dl-propranolol: an example of hemodynamic drug interaction.

1973 • 108 citations

The effect of lidocaine on atrioventricular and intraventricular conduction in man

1970 • 106 citations

The physiological disposition of lidocaine and its comparison in some respects with procaine.

1954 • 91 citations

The effects of lidocaine on the electrical and mechanical activity of the heart

1968 • 91 citations

Ventricular tachyarrhythmias and lignocaine prophylaxis in acute myocardial infarction. A clinical and therapeutic study.

1970 • 88 citations

Identification of glycinexylidide in patients treated with intravenous lidocaine

1973 • 71 citations

On the Metabolism of Lidocaine II. The Biotransformation of Lidocaine.

1961 • 68 citations

Studies on the Absorption, Distribution and Metabolism of Labelled Prilocaine and Lidocaine in some Animal Species

1966 • 68 citations

Cardiovascular effects of infusion of lidocaine on patients with heart disease

1969 • 66 citations

Plasma levels of lidocaine after intramuscular administration

1972 • 64 citations

Electrophysiological effects of lidocaine on distal Purkinje fibers of canine heart

1973 • 59 citations

Antiarrhythmic drugs. Part VII. Lidocaine as an antiarrhythmic agent

1965 • 58 citations

Central Nervous System Toxicity Induced by Lidocaine

1967 • 55 citations

Atrioventricular block with lidocaine therapy

1973 • 53 citations

Production of sinus arrest by lignocaine.

1971 • 50 citations

Sinus Standstill Following Intravenous Lidocaine Administration

1973 • 45 citations

Intramuscularly and orally administered lidocaine in the treatment of ventricular arrhythmias in acute myocardial infarction

1972 • 44 citations

The acute antiarrhythmic and toxic effects in mice and dogs of 2-ethylamino-2',6-'acetoxylidine (L-86), a metabolite of lidocaine.

1971 • 43 citations

Electrophysiologic effects of lidocaine on isolated canine and rabbit atrial tissue.

1971 • 43 citations

Relation between Plasma Lignocaine Levels and Induced Haemodynamic Changes

1969 • 41 citations

Sinoatrial Arrest due to Lidocaine in a Patient Receiving Quinidine

1972 • 40 citations

Lidocaine Metabolism in Normal and Phenobarbital-pretreated Dogs

1972 • 39 citations

PLASMA-LEVELS OF LIGNOCAINE AFTER INTRAMUSCULAR INJECTION

1968 • 38 citations

Haemodynamic effects of lignocaine in acute myocardial infarction.

1968 • 37 citations

Oxidative N -Dealkylation: A Mannich Intermediate in the Formation of a New Metabolite of Lidocaine in Man

1971 • 36 citations

Effect of lignocaine on conducting system of human heart.

1973 • 29 citations

Blood Lidocaine Levels and Kinetics following High-Dose Intramuscular Administration

1973 • 28 citations

Lidocaine Infusion in Acute Myocardial Infarction

1971 • 28 citations

Limitations of lignocaine in control of early ventricular dysrhythmias complicating acute myocardial infarction.

1972 • 20 citations

Alarming Ventricular Acceleration after Lidocaine Administration

1972 • 19 citations

The Effect of Lignocaine on the Stimulation Threshold and Conduction Disturbances in Patients Treated with Pacemaker

1969 • 18 citations

Hypersensitivity to lidocaine hydrochloride

1969 • 18 citations

The Circulatory Response to Lidocaine in Experimental Myocardial Infarction

1969 • 18 citations

LIGNOCAINE IN THE MANAGEMENT OF VENTRICULAR ARRHYTHMIAS

1969 • 10 citations

PLASMA-LIGNOCAINE LEVELS AFTER INTRAVENOUS AND INTRAMUSCULAR INJECTION

1970 • 10 citations

More About the “Allergic Reaction to Lidocain”

1970 • 4 citations

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