Isoelectric focusing of human platelet phospholipase C: Evidence for multimolecular forms

Inositol trisphosphate and diacylglycerol as second messengers

1984 • 3,535 citations

Production of diglyceride from phosphatidylinositol in activated human platelets.

1979 • 727 citations

The polyphosphoinositide phosphodiesterase of erythrocyte membranes

1981 • 614 citations

Thrombin-induced phosphodiesteratic cleavage of phosphatidylinositol bisphosphate in human platelets.

1983 • 394 citations

Hydrolysis of polyphosphoinositides by purified sheep seminal vesicle phospholipase C enzymes.

1984 • 225 citations

Evidence that phospholipid turnover is the signal transducing system coupled to serotonin-S2 receptor sites.

1985 • 206 citations

Phosphatidylinositol-4,5-bisphosphate phosphodiesterase and phosphomonoesterase activities of rat brain. Some properties and possible control mechanisms

1984 • 194 citations

Modulation of phosphatidylinositol-specific phospholipase C activity by phospholipid interactions, diglycerides, and calcium ions.

1982 • 158 citations

Changes in phosphatidylinositol-4,5-bisphosphate 10 seconds after stimulation of washed rabbit platelets with ADP

1982 • 95 citations

Resolution of myocardial phospholipase C into several forms with distinct properties

1983 • 89 citations

Properties and distribution of phosphatidylinositol-specific phospholipase c in human and horse platelets

1983 • 70 citations

Phosphatidylinositol 4,5-bisphosphate may represent the site of release of plasma membrane-bound calcium upon stimulation of human platelets

1984 • 59 citations

Heterogeneity of the calcium-dependent phosphatidylinositol phosphodiesterase in rat brain

1982 • 48 citations

Evidence for the formation of inositol 4‐monophosphate in stimulated human platelets

1985 • 42 citations

Proteolytic activation can produce a phosphatidylinositol phosphodiesterase highly sensitive to Ca2+

1982 • 35 citations

Possible regulation of phospholipase C activity in human platelets by phosphatidylinositol 4′,5′-bisphosphate

1984 • 35 citations

Heterogeneity of the calcium-dependent phosphatidylinositol-phosphodiesterase of rat liver and kidney, as revealed by column chromatofocusing

1982 • 20 citations

Beta-adrenergic-stimulated adenylate cyclase activity in normal and EBV-transformed lymphocytes

1985 • 11 citations

The effect of prostaglandins E1, I2 and F2α on the shape and phosphatidylinositol-4,5-bisphosphate metabolism of washed rabbit platelets

1982 • 9 citations