An Acquired Chemotactic Defect in Neutrophils from Patients Receiving Interleukin-2 Immunotherapy

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

A Progress Report on the Treatment of 157 Patients with Advanced Cancer Using Lymphokine-Activated Killer Cells and Interleukin-2 or High-Dose Interleukin-2 Alone

1987 • 2,769 citations

THE CHEMOTACTIC EFFECT OF MIXTURES OF ANTIBODY AND ANTIGEN ON POLYMORPHONUCLEAR LEUCOCYTES

1962 • 2,726 citations

Observations on the Systemic Administration of Autologous Lymphokine-Activated Killer Cells and Recombinant Interleukin-2 to Patients with Metastatic Cancer

1985 • 2,616 citations

Selective in Vitro Growth of T Lymphocytes from Normal Human Bone Marrows

1976 • 2,458 citations

Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes.

1982 • 2,228 citations

Two distinct monokines, interleukin 1 and tumor necrosis factor, each independently induce biosynthesis and transient expression of the same antigen on the surface of cultured human vascular endothelial cells.

1986 • 748 citations

Adoptive Immunotherapy of Established Pulmonary Metastases with LAK Cells and Recombinant Interleukin-2

1984 • 687 citations

The Severe and Moderate Phenotypes of Heritable Mac-1, LFA-1 Deficiency: Their Quantitative Definition and Relation to Leukocyte Dysfunction and Clinical Features

1985 • 644 citations

In vivo administration of purified human interleukin 2. II. Half life, immunologic effects, and expansion of peripheral lymphoid cells in vivo with recombinant IL 2.

1985 • 600 citations

Purified Human Granulocyte-Macrophage Colony-Stimulating Factor: Direct Action on Neutrophils

1984 • 506 citations

Laboratory Manual of Neutrophil Function

1986 • 443 citations

Successful immunotherapy of natural killer-resistant established pulmonary melanoma metastases by the intravenous adoptive transfer of syngeneic lymphocytes activated in vitro by interleukin 2.

1984 • 371 citations

Metastatic Renal Cancer Treated with Interleukin-2 and Lymphokine-Activated Killer Cells

1988 • 353 citations

Interleukin-2 and lymphokine-activated killer cell therapy of solid tumors: analysis of toxicity and management guidelines.

1989 • 349 citations

Human cutaneous T cell lymphoma and leukemia cell lines produce and respond to T cell growth factor

1981 • 340 citations

Expression of interleukin 2 receptors and binding of interleukin 2 by gamma interferon-induced human leukemic and normal monocytic cells.

1985 • 288 citations

Neutrophil Actin Dysfunction and Abnormal Neutrophil Behavior

1974 • 266 citations

A phase II study of interleukin-2 and lymphokine-activated killer cells in patients with metastatic malignant melanoma.

1989 • 240 citations

Endothelial activation during interleukin 2 immunotherapy. A possible mechanism for the vascular leak syndrome.

1988 • 225 citations

The Hyperimmunoglobulin E Recurrent-Infection (Jobʼs) Syndrome

1983 • 221 citations

Biosynthetic human GM-CSF modulates the number and affinity of neutrophil f-Met-Leu-Phe receptors.

1986 • 218 citations

Induction of circulating tumor necrosis factor (TNFα) as the mechanism for the febrile response to interleukin-2 (IL-2) in cancer patients

1988 • 210 citations

New Approaches to the Immunotherapy of Cancer Using Interleukin-2

1988 • 202 citations

PREDICTIVE VALUE OF SURVEILLANCE SKIN CULTURES IN TOTAL-PARENTERAL-NUTRITION-RELATED INFECTION

1982 • 193 citations

Recombinant human tumor necrosis factor-alpha. Regulation of N-formylmethionylleucylphenylalanine receptor affinity and function on human neutrophils.

1988 • 162 citations

The Chediak-Higashi Syndrome: Studies of Host Defenses

1972 • 146 citations

Human recombinant interleukin 1 beta has no effect on intracellular calcium or on functional responses of human neutrophils.

1987 • 131 citations

Nosocomial Sepsis Associated with Interleukin-2

1990 • 91 citations

Marked Disparity in Incidence of Bacterial Infections in Patients with the Acquired Immunodeficiency Syndrome Receiving Interleukin-2 or Interferon-γ

1988 • 74 citations

Toxicity of Immunotherapy with Interleukin-2 and Lymphokine-Activated Killer Cells

1988 • 51 citations

Interleukin 2 inhibits migration and stimulates respiratory burst and degranulation of human neutrophils in vitro

1987 • 29 citations

Modification of interactions between neutrophils and staphylococci by lysosomotropic weak bases

1985 • 13 citations

Calcium release associated with discharge of specific granule contents from human neutrophils

1988 • 6 citations