Humoral Links between Sleep and the Immune System

NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses

1998 • 5,178 citations

Control of Synaptic Strength by Glial TNFα

2002 • 1,277 citations

Interleukin-1 and Its Biologically Related Cytokines

1989 • 1,180 citations

The major acute phase reactants: C-reactive protein, serum amyloid P component and serum amyloid A protein

1994 • 1,030 citations

Sickness behavior as a new target for drug development

1992 • 866 citations

Cytokine-to-brain communication: A review & analysis of alternative mechanisms

1995 • 579 citations

“Inflammatory” Cytokines

2000 • 499 citations

Catecholamine Influences and Sympathetic Neural Modulation of Immune Responsiveness

1995 • 440 citations

Soluble TNF-α receptor 1 and IL-6 plasma levels in humans subjected to the sleep deprivation model of spaceflight

2001 • 438 citations

New Concepts on the Pathogenesis of Fever

1988 • 373 citations

Biochemical regulation of non-rapid-eye-movement sleep

2003 • 318 citations

Implications of immune-to-brain communication for sickness and pain

1999 • 249 citations

The distribution of growth‐hormone‐releasing factor (GRF) immunoreactivity in the central nervous system of the rat: An immunohistochemical study using antisera directed against rat hypothalamic GRF

1985 • 234 citations

Interleukin 1 alters rat sleep: temporal and dose-related effects

1991 • 223 citations

Microbial Products and Cytokines in Sleep and Fever Regulation

1994 • 215 citations

Lymphocyte Targeting of the Central Nervous System: A Review of Afferent and Efferent CNS‐Immune Pathways

1996 • 210 citations

Sleep: A Physiologic Role for IL‐1β and TNF‐α^a

1998 • 193 citations

The Mechanism of Action of Cytokines to Control the Release of Hypothalamic and Pituitary Hormones in Infection

2000 • 168 citations

Associations between the neuroendocrine and immune systems

1995 • 159 citations

Somnogenic, pyrogenic, and anorectic activities of tumor necrosis factor-alpha and TNF-alpha fragments

1992 • 143 citations

Diurnal variation of TNFα in the rat brain

1997 • 135 citations

Cytokines and the acute phase response to influenza virus in mice

1995 • 132 citations

Corticotropin-releasing factor attenuates interleukin 1-induced sleep and fever in rabbits

1989 • 128 citations

Cytokine–cytokine interactions and the brain

2000 • 124 citations

Sleep electroencephalogram delta-frequency amplitude, night plasma levels of tumor necrosis factor alpha, and human immunodeficiency virus infection.

1995 • 122 citations

Prolactin and Rapid Eye Movement Sleep Regulation

1995 • 113 citations

Sleep and Cerebrospinal Fluid Interleukin-1-Like Activity in the Cat

1988 • 113 citations

Blockade of corticotropin-releasing hormone receptors reduces spontaneous waking in the rat

1998 • 112 citations

Rat Strain Differences Suggest a Role for Corticotropin-Releasing Hormone in Modulating Sleep

1997 • 103 citations

Intrapreoptic Microinjection of GHRH or Its Antagonist Alters Sleep in Rats

1999 • 100 citations

Brain-derived neurotrophic factor enhances spontaneous sleep in rats and rabbits

1999 • 94 citations

Adenosine, prolonged wakefulness, and A1-activated NF-κB DNA binding in the basal forebrain of the rat

2001 • 94 citations

CRF/NPY interactions: A potential role in sleep dysregulation in depression and anxiety

1997 • 92 citations

Sleep function

2003 • 91 citations

Intrapreoptic microinjection of TNF-α enhances non-REM sleep in rats

2002 • 84 citations

Nuclear factor-κB inhibitor peptide inhibits spontaneous and interleukin-1β-induced sleep

2000 • 83 citations

Behavioral and neural influences on cellular immune responses: effects of stress and interleukin-1.

1989 • 83 citations

Nuclear factor-κB-like activity increases in murine cerebral cortex after sleep deprivation

1999 • 78 citations

The change of interleukin-6 and tumor necrosis factor in patients with obstructive sleep apnea syndrome

2000 • 75 citations

Modulation by Cytokines of Glucocorticoid Action

1999 • 74 citations

GHRH and IL1β increase cytoplasmic Ca2+ levels in cultured hypothalamic GABAergic neurons

2002 • 71 citations

Hypothalamic growth hormone-releasing hormone mRNA varies across the day in rats

1996 • 66 citations

Interleukin-18 promotes sleep in rabbits and rats

2001 • 66 citations

Pre-eclampsia is Associated with Marked Alterations in Sleep Architecture

2000 • 63 citations

Diurnal variations and sleep deprivation-induced changes in rat hypothalamic GHRH and somatostatin contents

1999 • 62 citations

Thermoregulation and Sleep

1997 • 61 citations

Growth-Hormone-Releasing Hormone Mediates the Sleep-Promoting Activity of Interleukin-1 in Rats

1995 • 60 citations

Corticotropin-Releasing Hormone Inhibition of Growth Hormone-Releasing Hormone-Induced Growth Hormone Release in Man*

1990 • 53 citations

“Recovery” function of sleep: Effects of purified human interleukin-1 on the sleep and febrile response of cats

1989 • 40 citations

Interleukin 1 alpha and an interleukin 1 beta fragment are somnogenic

1990 • 39 citations

Nerve growth factor enhances sleep in rabbits

1999 • 37 citations

Fluorescent stilbene (BADS) binding proteins in anion-transporting epithelia

1990 • 34 citations

Cerebral blood flow and metabolism in sleep

1989 • 34 citations

Sleep deprivation increases rat hypothalamic growth hormone-releasing hormone mRNA

1998 • 34 citations

Rat Strains that Differ in Corticotropin-Releasing Hormone Production Exhibit Different Sleep-Wake Responses to Interleukin 1

2001 • 32 citations

IL-1 is a mediator of increases in slow-wave sleep induced by CRH receptor blockade

2000 • 32 citations

Tumor necrosis factor receptor fragment attenuates interferon-γ-induced non-REM sleep in rabbits

2001 • 30 citations

Exchange of Peptides Between the Circulation and the Nervous System: Role of the Blood-Brain Barrier

1990 • 27 citations

Acidic fibroblast growth factor (FGF) but not basic FGF induces sleep and fever in rabbits

1995 • 18 citations

Continuous intracerebroventricular administration of a corticotropin releasing hormone antagonist amplifies spontaneous growth hormone pulses in the rat

1997 • 17 citations

Sleep loss alters hypothalamic growth hormone-releasing hormone receptors in rats

2002 • 12 citations

Deleted Work

1955 • 0 citations