Syntheses of All Four Possible Diastereomers of Etoposide and Its Aminoglycosidic Analogues via Optical Resolution of (±) -Podophyllotoxin by Glycosidation with D- and L-Sugars

Hitoshi Saitô; Yoshio Nishimura; Shinichi Kondo; HAMAO UMEZAWA

doi:10.1246/cl.1987.799

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Syntheses of All Four Possible Diastereomers of Etoposide and Its Aminoglycosidic Analogues via Optical Resolution of (±) -Podophyllotoxin by Glycosidation with D- and L-Sugars

Hitoshi Saitô, Yoshio Nishimura, Shinichi Kondo, HAMAO UMEZAWA

DOI: 10.1246/cl.1987.799

Chemistry Letters

Data up to Jan 2025

Published1987

Citations18

References7

Fields

Chemistry Medicine Computer science Stereochemistry Combinatorial chemistry Surgery

Total Citations Per Year

Abstract

References (7)

Über ein neues Glykosidierungsverfahren Synthese von Epipodophyllotoxin‐β‐<scp>D</scp>‐glucopyranosid. 21. Mitt. Über mitosehemmende Naturstoffe [1]

1968 • 58 citations

VP16-213 (Etoposide)

1982 • 48 citations

A stereocontrolled synthesis of antineoplastic podophyllum lignans

1981 • 41 citations

Studies on lignan lactone antitumor agents. II Synthesis of N-alkylamino- and 2,6-dideoxy-2-aminoglycosidic lignan variants related to podophyllotoxin.

1986 • 26 citations

A stereo- and regiocontrolled synthesis of Podophyllum lignans

1980 • 24 citations

Studies on lignan lactone antitumor agents. I Synthesis of aminoglycosidic lignan variants related to podophyllotoxin.

1986 • 14 citations

VM26: Phase I and II studies

1982 • 13 citations

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