Neuroendocrine Influences and Repercussions of the Menopause

Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease

1996 • 1,640 citations

The Neuroendocrine Control of the Menstrual Cycle

1980 • 1,288 citations

Cell Membrane and Nuclear Estrogen Receptors (ERs) Originate from a Single Transcript: Studies of ERα and ERβ Expressed in Chinese Hamster Ovary Cells

1999 • 1,046 citations

A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease

1997 • 965 citations

Gender-Linked Brain Injury in Experimental Stroke

1998 • 730 citations

Follicular Depletion During the Menopausal Transition: Evidence for Accelerated Loss and Ultimate Exhaustion*

1987 • 704 citations

Estradiol reduces calcium currents in rat neostriatal neurons via a membrane receptor

1996 • 638 citations

Estradiol Protects against Ischemic Injury

1998 • 548 citations

Estrogens may reduce mortality and ischemic damage caused by middle cerebral artery occlusion in the female rat

1997 • 512 citations

Characterization of reproductive hormonal dynamics in the perimenopause.

1996 • 498 citations

Ovarian steroids and the brain

1997 • 481 citations

Rapid Membrane Effects of Steroids in Neuroblastoma Cells: Effects of Estrogen on Mitogen Activated Protein Kinase Signalling Cascade and c-fos Immediate Early Gene Transcription

1997 • 478 citations

Regulation of Dendritic Spine Density in Cultured Rat Hippocampal Neurons by Steroid Hormones

1996 • 402 citations

Nongenomic Actions of Steroid Hormones in Reproductive Tissues*

1998 • 375 citations

Estrogen-Mediated Neuroprotection After Experimental Stroke in Male Rats

1998 • 362 citations

Decreased inhibin B secretion is associated with the monotropic FSH rise in older, ovulatory women: a study of serum and follicular fluid levels of dimeric inhibin A and B in spontaneous menstrual cycles.

1996 • 358 citations

17β-Estradiol Potentiates Kainate-Induced Currents via Activation of the cAMP Cascade

1996 • 347 citations

Perimenopause: The Complex Endocrinology of the Menopausal Transition

1998 • 331 citations

Estrogen protects primary cortical neurons from glutamate toxicity

1996 • 329 citations

Circadian Neural Rhythms in Mammals

1985 • 306 citations

Morphological plasticity of dendritic spines in central neurons is mediated by activation of cAMP response element binding protein

1997 • 292 citations

Estrogen effects on cognition in menopausal women

1997 • 292 citations

Reproductive aging: accelerated ovarian follicular development associated with a monotropic follicle-stimulating hormone rise in normal older women.

1996 • 284 citations

Estrogen rapidly induces the phosphorylation of the cAMP response element binding protein in rat brain.

1996 • 283 citations

17α-Estradiol Exerts Neuroprotective Effects on SK-N-SH Cells

1997 • 259 citations

Sex Differences in Postischemic Neuronal Necrosis in Gerbils

1991 • 253 citations

The epidemiology of estrogen replacement therapy and Alzheimer's disease

1997 • 230 citations

Estrogenic Effects on Memory in Women^a

1994 • 216 citations

Effects of gender and estradiol treatment on focal brain ischemia

1998 • 215 citations

Hormones, mood, and cognitive functioning in postmenopausal women

1996 • 214 citations

Nuclear estrogen receptor-independent neuroprotection by estratrienes: a novel interaction with glutathione

1998 • 175 citations

Transcriptional Effects of Estrogen on Neuronal Neurotensin Gene Expression Involve cAMP/Protein Kinase A-Dependent Signaling Mechanisms

1998 • 171 citations

Nongenomic Actions of Steroid Hormones in Reproductive Tissues

1998 • 164 citations

Estrogen: nontranscriptional signaling pathway.

1997 • 156 citations

Characterization of the LH Surge in Middle-Aged Female Rats1

1980 • 151 citations

Estrogen replacement therapy and stroke

1995 • 145 citations

Decreased inhibin B secretion is associated with the monotropic FSH rise in older, ovulatory women: a study of serum and follicular fluid levels of dimeric inhibin A and B in spontaneous menstrual cycles

1996 • 141 citations

Low concentrations of estradiol reduce β-amyloid (25–35)-induced toxicity, lipid peroxidation and glucose utilization in human SK-N-SH neuroblastoma cells

1997 • 133 citations

Alterations in Proestrous LH, FSH, and Prolactin Surges in Middle-Aged Rats

1982 • 131 citations

Aging Alters the Rhythmic Expression of Vasoactive Intestinal Polypeptide mRNA But Not Arginine Vasopressin mRNA in the Suprachiasmatic Nuclei of Female Rats

1998 • 120 citations

Aging of Hypothalamic-Pituitary-Ovarian Function in the Rat

1972 • 120 citations

Alterations in ovarian steroid and gonadotrophin secretion preceding the cessation of regular oestrous cycles in ageing female rats

1984 • 116 citations

Reinitiation of Estrous Cycles in Old Constant-Estrous Rats by Central-Acting Drugs

1973 • 103 citations

Ovarian follicular development and the follicular fluid hormones and growth factors in normal women of advanced reproductive age.

1996 • 101 citations

Age effects of follicle-stimulating hormone and pulsatile luteinizing hormone secretion across the menstrual cycle of premenopausal women.

1996 • 101 citations

Effects of Hypothalamic Stimulation, Hormones, and Drugs on Ovarian Function in Old Female Rats

1969 • 97 citations

Age-Related Changes in Pulsatile Luteinizing Hormone Release Precede the Transition to Estrous Acyclicity and Depend upon Estrous Cycle History*

1990 • 93 citations

Primordial Follicles with Normal Oocytes in the Ovaries of Postmenopausal Women†

1975 • 85 citations

Estrogens in the Pathogenesis and Treatment of Alzheimer's Disease in Postmenopausal Women

1994 • 79 citations

Aging of the female reproductive system: a window into brain aging.

1997 • 77 citations

Age related changes in the female reproductive cycle

1994 • 76 citations

The menopause and osteoporosis

1996 • 73 citations

Characteristics of luteinizing hormone secretion in younger versus older premenopausal women

1998 • 68 citations

Estrogen: Effects on the cardiovascular tree

1996 • 60 citations

Do Aging Changes in the Preoptic Area Contribute to Loss of Cyclic Endocrine Function?

1977 • 50 citations

Age effects of follicle-stimulating hormone and pulsatile luteinizing hormone secretion across the menstrual cycle of premenopausal women

1996 • 45 citations

Prolongation and Cessation of Estrous Cycles in Aging C57BL/6J Mice are Differentially Regulated Events

1986 • 45 citations

Ovarian follicular development and the follicular fluid hormones and growth factors in normal women of advanced reproductive age

1996 • 39 citations

Relation of Neuroendocrine System to Reproductive Decline in Female Rats

1983 • 34 citations

Luteinizing hormone-releasing hormone gene expression differs in young and middle-aged females on the day of a steroid-induced LH surge

1997 • 34 citations

Age-associated increases in serum follicle-stimulating hormone levels on estrus are accompanied by a reduction in the ovarian secretion of inhibin

1987 • 33 citations