Pharmacodynamic study of F(ab')2 fragments of murine monoclonal antibody 7E3 directed against human platelet glycoprotein IIb/IIIa in patients with unstable angina pectoris.

Gerinnungsphysiologische Schnellmethode zur Bestimmung des Fibrinogens

1957 • 3,280 citations

Plaque fissuring--the cause of acute myocardial infarction, sudden ischaemic death, and crescendo angina.

1985 • 2,003 citations

Secondary prevention of vascular disease by prolonged antiplatelet treatment

1988 • 962 citations

A new murine monoclonal antibody reports an activation-dependent change in the conformation and/or microenvironment of the platelet glycoprotein IIb/IIIa complex.

1985 • 593 citations

Rapid and sustained coronary artery recanalization with combined bolus injection of recombinant tissue-type plasminogen activator and monoclonal antiplatelet GPIIb/IIIa antibody in a canine preparation.

1988 • 394 citations

Abolition of in vivo platelet thrombus formation in primates with monoclonal antibodies to the platelet GPIIb/IIIa receptor. Correlation with bleeding time, platelet aggregation, and blockade of GPIIb/IIIa receptors.

1989 • 246 citations

Monoclonal antibody against the platelet glycoprotein (GP) IIb/IIIa receptor prevents coronary artery reocclusion after reperfusion with recombinant tissue-type plasminogen activator in dogs.

1988 • 243 citations

Antithrombotic effect of a monoclonal antibody to the platelet glycoprotein IIb/IIIa receptor in an experimental animal model

1986 • 232 citations

Cellular adhesion: GPIIb-IIIa as a prototypic adhesion receptor.

1989 • 187 citations

Inhibition of dog platelet function by in vivo infusion of F(ab')2 fragments of a monoclonal antibody to the platelet glycoprotein IIb/IIIa receptor

1985 • 172 citations

Increased thromboxane biosynthesis during coronary thrombolysis. Evidence that platelet activation and thromboxane A2 modulate the response to tissue-type plasminogen activator in vivo.

1989 • 171 citations

Effects of monoclonal antibodies against the platelet glycoprotein IIb/IIIa complex on thrombosis and hemostasis in the baboon.

1988 • 167 citations

A randomized, blinded, placebo-controlled trial of recombinant human tissue-type plasminogen activator in patients with unstable angina pectoris.

1987 • 147 citations

The coronary thrombus: Its origin and fate

1971 • 98 citations

Immunologic and biochemical characterization of homozygous and heterozygous Glanzmann thrombasthenia in the Iraqi‐Jewish and Arab populations of Israel: comparison of techniques for carrier detection

1986 • 74 citations

Plasma membrane GPIIb/IIIa. Evidence for a cycling receptor pool.

1990 • 60 citations

Inhibition of Human Platelet Function in Vivo with a Monoclonal Antibody

1988 • 57 citations

Antiplatelet monoclonal F(ab′)2 antibody directed against the platelet GPIIb/IIIa receptor complex prevents coronary artery thrombosis in the canine heart

1989 • 54 citations

Monoclonal antibody—induced inhibition of platelet function: Effects on hemostasis and vascular graft thrombosis in baboons

1988 • 23 citations

Platelet Reactivity in Unstable Coronary Artery Disease

1987 • 19 citations

Antithrombotic effect of a monoclonal antibody to the platelet glycoprotein IIb/IIIa receptor in an experimental animal model

1986 • 8 citations