Adenosine A_2A Receptor Gene Disruption Provokes Marked Changes in Melanocortin Content and Pro‐Opiomelanocortin Gene Expression

Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor

1997 • 906 citations

Antidepressants and Hypothalamic-Pituitary-Adrenocortical Regulation

1996 • 829 citations

Adenosine, Adenosine Receptors and the Actions of Caffeine *

1995 • 563 citations

Tissue distribution of adenosine receptor mRNAs in the rat

1996 • 560 citations

Adenosine receptor subtypes

1993 • 418 citations

Immunohistochemical localization of adenosine A2A receptors in the rat central nervous system

1998 • 374 citations

Effect of γ-butyrobetaine on fatty liver in juvenile visceral steatosis mice

2001 • 369 citations

alpha-Melanocyte stimulating hormone: immunohistochemical identification and mapping in neurons of rat brain.

1978 • 352 citations

Direct autoradiographic localization of adenosine A2 receptors in the rat brain using the A2-selective agonist, [3H]CGS 21680

1989 • 344 citations

Molecular Cloning and Characterization of a Rat A₁-Adenosine Receptor that is Widely Expressed in Brain and Spinal Cord

1991 • 341 citations

Adenosine A2 receptor-mediated excitatory actions on the nervous system

1996 • 303 citations

Identification of proopiomelanocortin neurones in rat hypothalamus by in situ cDNA-mRNA hybridization

1983 • 279 citations

Adenosine A2 receptors regulate the gene expression of striatopallidal and striatonigral neurons

1993 • 248 citations

Distribution of adenosine receptors in the postmortem human brain: An extended autoradiographic study

1997 • 229 citations

Biological and Radioimmunological Evidence for Melanocyte Stimulating Hormones (MSH) of Extrapituitary Origin in the Rat Brain

1978 • 216 citations

Hyper‐Reactive Hypothalamo‐Pituitary‐Adrenocortical Axis in Rats Bred for High Anxiety‐Related Behaviour

1999 • 198 citations

Behavioral effects of α-MSH and MCH after central administration in the female rat

1996 • 194 citations

Adenosine A2A receptor stimulation enhances striatal extracellular glutamate levels in rats

1995 • 182 citations

Immunocytochemical localization of ACTH perikarya in nucleus tractus solitarius: evidence for a second opiocortin neuronal system

1983 • 168 citations

Molecular cloning and expression of the cDNA for a novel A2-adenosine receptor subtype

1992 • 156 citations

Autoradiographic evidence for G-protein coupled A2-receptors in rat neostriatum using [3H]-CGS 21680 as a ligand

1990 • 154 citations

Physiological and pharmacological properties of adenosine: Therapeutic implications

1991 • 145 citations

A2a adenosine receptor gene expression in developing rat brain

1993 • 138 citations

Evidence for the presence of excitatory A2 adenosine receptors in the rat hippocampus

1992 • 120 citations

Pro-opiocortin fragments in human and rat brain: β-endorphin and α-MSH are the predominant peptides

1980 • 114 citations

Further characterization of the binding of the adenosine receptor agonist [3H]CGS 21680 to rat brain using autoradiography

1995 • 106 citations

Direct radioimmunoassays for plasma corticosterone and aldosterone in frog. I. Validation of the methods and evidence for daily rhythms in a natural environment

1982 • 99 citations

A2 adenosine receptors: their presence and neuromodulatory role in the central nervous system

1996 • 87 citations

Adenosine receptor subtypes in the brainstem mediate distinct cardiovascular response patterns

1991 • 85 citations

Adenosine Receptors in the Central Nervous System

1995 • 68 citations

GABAergic and catecholaminergic innervation of mediobasal hypothalamic β-endorphin cells projecting to the medial preoptic area

1992 • 57 citations

Adenosine and Pituitary-Adrenocortical Axis Activity in the Rat

1989 • 45 citations

Regulation of Proopiomelanocortin Gene Expression in Rat Brain and Pituitary as Studied by In Situ Hybridization

1993 • 43 citations

In vivo labelling of the adenosine A_2A receptor in mouse brain using the selective antagonist [³H]SCH 58261

2001 • 43 citations

Stimulatory effect of caffeine on the hypothalamo-pituitary-adrenocortical axis in the rat

1989 • 41 citations

Further characterization of [³H]‐CGS 21680 binding sites in the rat striatum and cortex

1995 • 40 citations

Regulation of α‐Melanocyte‐Stimulating Hormone Release from Hypothalamic Neurons^a

1993 • 40 citations

Contrasting effects of org 2766 and α-MSH on social and exploratory behavior in the rat

1981 • 38 citations

The distribution of alpha-melanocyte stimulating hormone (alpha-MSH) in the central nervous system of the rat: an immunohistochemical study--I. Forebrain and upper brain stem.

1983 • 37 citations

Stimulation of the hypothalamo‐pituitary‐adrenal axis in the rat by three selective type‐4 phosphodiesterase inhibitors: in vitro and in vivo studies

1997 • 35 citations

Adenosine regulates the release of adrenocorticotropic hormone (ACTH) from cultured anterior pituitary cells

1989 • 31 citations

Adenosine-Regulated Cell Proliferation in Pituitary Folliculostellate and Endocrine Cells: Differential Roles for the A1 and A2B Adenosine Receptors

2002 • 23 citations

Adenosine-Sensitive Adenylate Cyclase in Rat Anterior Pituitary

1985 • 23 citations

Interrelations between Hypothalamic Somatostatin and Proopiomelanocortin Neurons

1998 • 21 citations

Visualization of gamma-aminobutyric acid A receptors on proopiomelanocortin-producing neurons in the rat hypothalamus

1994 • 19 citations

Synaptic association between enkephalin-containing axon terminals and proopiomelanocortin-containing neurons in the arcuate nucleus of rat hypothalamus

1987 • 19 citations

Synaptic regulation of hypothalamic neurons containing ACTH by substance P

1984 • 18 citations

Social and exploratory behaviour in the rat after septal administration of ORG 2766 and ACTH4–10

1983 • 17 citations

Characterization of α-melanocyte-stimulating hormone (α-MSH)-like peptides in discrete regions of the rat brain. In vitro release of α-MSH from perifused hypothalamus and amygdala

1990 • 17 citations

Inhibitory effect of adenosine on electrical activity of frog melanotrophs mediated through A1 purinergic receptors.

1994 • 17 citations

Opioid systems in the amygdala can serve as substrate for the behavioral effects of the ACTH-(4-–9) analog ORG 2766

1989 • 15 citations

Effect of adenosine analogues on plasma corticosterone concentration in rats

1992 • 13 citations

Adenosine Inhibits Alpha‐Melanocyte‐Stimulating Hormone Release from Frog Pituitary Melanotrophs. Evidence for the Involvement of A₁ Adenosine Receptors Negatively Coupled to Adenylate Cyclase

1992 • 12 citations

Ionic, neuronal and endocrine influences on the proopiomelanocortin system of the hypothalamus

1990 • 12 citations

Changes in α-melanotropin in discrete brain areas of isolated aggressive mice

1982 • 9 citations

Effect of adenosine and its metabolites on the hypothalamo-pituitary-adrenal axis

1995 • 9 citations

Electron-Microscopic Cytochemistry of the Catecholaminergic Innervation of ACTH-Containing Neurons in the Rat Hypothalamic Arcuate Nucleus

1987 • 6 citations