MxiD, an outer membrane protein necessary for the secretion of the Shigella flexneri Ipa invasins

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Experiments in molecular genetics

1972 • 28,260 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

Lounging in a lysosome: the intracellular lifestyle of Coxiella burnetii

2007 • 11,720 citations

Improved tools for biological sequence comparison.

1988 • 11,455 citations

A novel suicide vector and its use in construction of insertion mutations: osmoregulation of outer membrane proteins and virulence determinants in Vibrio cholerae requires toxR

1988 • 2,150 citations

Quantitative evaluation ofEscherichia colihost strains for tolerance to cytosine methylation in plasmid and phage recombinants

1989 • 744 citations

Involvement of a plasmid in the invasive ability of Shigella flexneri

1982 • 733 citations

Identification of icsA, a plasmid locus of Shigella flexneri that governs bacterial intra- and intercellular spread through interaction with F-actin.

1989 • 724 citations

The Release of Enzymes by Osmotic Shock from Escherichia coli in Exponential Phase

1966 • 672 citations

EPITHELIAL CELL PENETRATION AS AN ESSENTIAL STEP IN THE PATHOGENESIS OF BACILLARY DYSENTERY

1964 • 628 citations

Multiplication of Shigella flexneri within HeLa cells: lysis of the phagocytic vacuole and plasmid-mediated contact hemolysis

1986 • 509 citations

Entry of Shigella flexneri into HeLa cells: evidence for directed phagocytosis involving actin polymerization and myosin accumulation

1987 • 327 citations

IpaB of Shigella flexneri causes entry into epithelial cells and escape from the phagocytic vacuole.

1992 • 316 citations

Cloning of plasmid DNA sequences involved in invasion of HeLa cells by Shigella flexneri

1985 • 306 citations

Analysis of virC, an operon involved in the secretion of Yop proteins by Yersinia enterocolitica

1991 • 301 citations

Plaque formation by virulent Shigella flexneri

1985 • 253 citations

virG, a plasmid-coded virulence gene of Shigella flexneri: identification of the virG protein and determination of the complete coding sequence

1989 • 240 citations

Temperature-dependent expression of virulence genes in Shigella species

1984 • 237 citations

Serum immune response to Shigella protein antigens in rhesus monkeys and humans infected with Shigella spp

1986 • 233 citations

Virulence-associated genetic regions comprising 31 kilobases of the 230-kilobase plasmid in Shigella flexneri 2a

1988 • 195 citations

Surface presentation of Shigella flexneri invasion plasmid antigens requires the products of the spa locus

1992 • 183 citations

icsB: a Shigella flexneri virulence gene necessary for the lysis of protrusions during intercellular spread

1992 • 178 citations

Identification and antigenic characterization of virulence-associated, plasmid-coded proteins of Shigella spp. and enteroinvasive Escherichia coli

1985 • 161 citations

Temperature‐regulated expression of invasion genes in Shigella flexneri is controlled through the transcriptional activation of the virB gene on the large plasmid

1991 • 146 citations

Protein Secretion by Gram-negative Bacteria

1989 • 142 citations

Genetic basis of virulence in Shigella species.

1991 • 139 citations

Two novel virulence loci, mxiA and mxiB, in Shigella flexneri 2a facilitate excretion of invasion plasmid antigens

1991 • 137 citations

Genetic and Molecular Basis of Epithelial Cell Invasion by Shigella Species

1991 • 132 citations

mxiA of Shigella flexneri 2a, which facilitates export of invasion plasmid antigens, encodes a homolog of the low-calcium-response protein, LcrD, of Yersinia pestis

1992 • 122 citations

Characterization of invasion plasmid antigen genes (ipaBCD) from Shigella flexneri.

1988 • 121 citations

Functional organization and nucleotide sequence of virulence Region-2 on the large virulence plasmid in Shigella flexneri 2a

1989 • 114 citations

Intercellular spread of Shigella flexneri through a monolayer mediated by membranous protrusions and associated with reorganization of the cytoskeletal protein vinculin

1991 • 110 citations

Localization of Plasmid Loci Necessary for the Entry of Shigella flexneri into HeLa Cells, and Characterization of One Locus Encoding Four Immunogenic Polypeptides

1987 • 94 citations

Nucleotide sequence and genetic organization of the genome of the N-specific filamentous bacteriophage IKe

1985 • 93 citations

Cloning and characterization of a gene required for the secretion of extracellular enzymes across the outer membrane by Xanthomonas campestris pv. campestris

1992 • 91 citations

Secretion and membrane integration of a filamentous phage-encoded morphogenetic protein

1990 • 84 citations

Nucleotide sequence of the invasion plasmid antigen B and C genes (ipaB and ipaC) of Shigella flexneri

1988 • 79 citations

Nucleotide sequence of the genome of Pf3, an IncP-1 plasmid-specific filamentous bacteriophage of Pseudomonas aeruginosa

1985 • 72 citations

Identification of Shigella invasion genes by isolation of temperature-regulated inv::lacZ operon fusions

1989 • 65 citations

Identification and characterization of B-cell epitopes of IpaC, an invasion-associated protein of Shigella flexneri

1992 • 53 citations

Nucleotide sequence of invasion plasmid antigen geneipaAfromShigella flexneri5

1990 • 26 citations