Evidence for the involvement of protein kinase activity in transforming growth factor-beta signal transduction.

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

The Transforming Growth Factor-beta Family

1990 • 3,028 citations

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

1984 • 2,728 citations

Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase

1986 • 2,445 citations

Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family

1985 • 2,145 citations

Transforming growth factor beta

2011 • 1,990 citations

CREB: a Ca ²⁺ -Regulated Transcription Factor Phosphorylated by Calmodulin-Dependent Kinases

1991 • 1,476 citations

The E2F transcription factor is a cellular target for the RB protein

1991 • 1,461 citations

Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB

1988 • 1,321 citations

Peptide Growth Factors and Their Receptors

1991 • 1,221 citations

Growth inhibition by TGF-β linked to suppression of retinoblastoma protein phosphorylation

1990 • 812 citations

Growth Inhibitor from BSC-1 Cells Closely Related to Platelet Type β Transforming Growth Factor

1984 • 779 citations

A gene activated by growth factors is related to the oncogene v-jun.

1988 • 771 citations

Expression cloning of an activin receptor, a predicted transmembrane serine kinase

1991 • 760 citations

Disappearance of Ca2+-sensitive, phospholipid-dependent protein kinase activity in phorbol ester-treated 3T3 cells

1984 • 643 citations

TGF-β1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains

1990 • 612 citations

Suppression of Tumorigenicity of Human Prostate Carcinoma Cells by Replacing a Mutated RB Gene

1990 • 606 citations

SV40 large T antigen binds preferentially to an underphosphorylated member of the retinoblastoma susceptibility gene product family

1989 • 508 citations

[The role of protein kinase C in cell surface signal transduction and tumor promotion].

1986 • 508 citations

Purification and characterization of two cartilage-inducing factors from bovine demineralized bone.

1985 • 503 citations

The retinoblastoma protein copurifies with E2F-I, an E1A-regulated inhibitor of the transcription factor E2F

1991 • 446 citations

Transforming growth factor beta 1 suppression of c-myc gene transcription: role in inhibition of keratinocyte proliferation.

1990 • 397 citations

Concomitant loss of transforming growth factor (TGF)-beta receptor types I and II in TGF-beta-resistant cell mutants implicates both receptor types in signal transduction.

1990 • 319 citations

Isolation of the pericellular matrix of human fibroblast cultures.

1979 • 302 citations

Cyclin A and the retinoblastoma gene product complex with a common transcription factor

1991 • 296 citations

Responsiveness to transforming growth factor-beta (TGF-beta) restored by genetic complementation between cells defective in TGF-beta receptors I and II

1991 • 252 citations

Enhanced jun gene expression is an early genomic response to transforming growth factor beta stimulation.

1989 • 213 citations

Plasminogen activator inhibitor type‐1 : reactive center and amino‐terminal heterogeneity determined by protein and cDNA sequencing

1986 • 207 citations

Transforming growth factor beta 1 inhibition of p34cdc2 phosphorylation and histone H1 kinase activity is associated with G1/S-phase growth arrest.

1991 • 203 citations

The antiproliferative effect of type beta transforming growth factor occurs at a level distal from receptors for growth-activating factors.

1986 • 177 citations

Regulation of transforming growth factor beta 1 gene expression by the product of the retinoblastoma-susceptibility gene.

1991 • 159 citations

Rapid inactivation of the plasminogen-activator inhibitor upon secretion from cultured human endothelial cells

1986 • 104 citations

Early gene responses to transforming growth factor-beta in cells lacking growth-suppressive RB function.

1991 • 104 citations

Control of junB and extracellular matrix protein expression by transforming growth factor-beta 1 is independent of simian virus 40 T antigen-sensitive growth-sensitive growth-inhibitory events.

1991 • 102 citations

Isoquinolinesulfonamides, Novel and Potent Inhibitors of Cyclic Nucleotide-Dependent Protein Kinase and Protein Kinase C

1984 • 98 citations

TGF-beta 1 induces phosphorylation of the cyclic AMP responsive element binding protein in ML-CCl64 cells.

1991 • 88 citations