Mutation of serum response factor phosphorylation sites and the mechanism by which its DNA-binding activity is increased by casein kinase II.

Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes

1986 • 6,284 citations

Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB

1988 • 1,321 citations

Elution of proteins from sodium dodecyl sulfate-polyacrylamide gels, removal of sodium dodecyl sulfate, and renaturation of enzymatic activity: Results with sigma subunit of Escherichia coli RNA polymerase, wheat germ DNA topoisomerase, and other enzymes

1980 • 1,256 citations

Activation in vitro of NF-κB" by phosphorylation of its inhibitor IκB"

1990 • 1,202 citations

Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element

1988 • 983 citations

Identification of a protein-binding site that mediates transcriptional response of the c-fos gene to serum factors

1986 • 883 citations

Transient accumulation of c-fos RNA following serum stimulation requires a conserved 5′ element and c-fos 3′ sequences

1985 • 871 citations

Single-stranded DNA ‘blue’ T7 promoter plasmids: a versatile tandem promoter system for cloning and protein engineering

1986 • 816 citations

Reduced levels of hsp90 compromise steroid receptor action in vivo

1990 • 794 citations

Effect of protein synthesis inhibitors on growth factor activation of c-fos, c-myc, and actin gene transcription.

1986 • 548 citations

Multiple protein-binding sites in the 5'-flanking region regulate c-fos expression.

1986 • 516 citations

A movable and regulable inactivation function within the steroid binding domain of the glucocorticoid receptor

1988 • 427 citations

Calcium and growth factor pathways of c-fos transcriptional activation require distinct upstream regulatory sequences.

1988 • 404 citations

Occupation of the c-fos serum response element in vivo by a multi-protein complex is unaltered by growth factor induction

1989 • 346 citations

Inducible binding of a factor to the c-fos enhancer

1986 • 310 citations

c-fos Sequence Necessary for Basal Expression and Induction by Epidermal Growth Factor, 12-O-Tetradecanoyl Phorbol-13-Acetate and the Calcium Ionophore

1987 • 304 citations

Activation of casein kinase II in response to insulin and to epidermal growth factor.

1987 • 299 citations

The c-fos serum response element responds to protein kinase C-dependent and -independent signals but not to cyclic AMP.

1988 • 245 citations

Mutation of the c-fos gene dyad symmetry element inhibits serum inducibility of transcription in vivo and the nuclear regulatory factor binding in vitro.

1987 • 238 citations

Insulin-like growth factor I and insulin rapidly increase casein kinase II activity in BALB/c 3T3 fibroblasts.

1988 • 207 citations

Casein kinase II enhances the DNA binding activity of serum response factor.

1990 • 181 citations

Phosphorylation of serum response factor, a factor that binds to the serum response element of the c-FOS enhancer.

1988 • 180 citations

Serum-stimulated cell growth causes oscillations in casein kinase II activity

1989 • 171 citations

Regulation of casein kinase II activity by epidermal growth factor in human A-431 carcinoma cells

1989 • 147 citations

Regulation of SV40 DNA replication by phosphorylation of T antigen.

1987 • 130 citations

Casein Kinase II as a Potentially Important Enzyme Concerned with Signal Transduction

1988 • 128 citations

Evidence of Changes in Protease Sensitivity and Subunit Exchange Rate on DNA Binding by C/EBP

1990 • 127 citations

DNA-binding activity of the adenovirus-induced E4F transcription factor is regulated by phosphorylation.

1989 • 104 citations

Amino acid sequence of the beta subunit of bovine lung casein kinase II.

1987 • 75 citations

Transcriptional Regulation of c-fos

1988 • 35 citations