Accumulation of human apolipoprotein E in the plasma of transgenic mice.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodies

1966 • 4,504 citations

Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology

1988 • 3,984 citations

Apolipoprotein E mRNA is abundant in the brain and adrenals, as well as in the liver, and is present in other peripheral tissues of rats and marmosets.

1985 • 500 citations

A glimpse at chromosomal order

1987 • 423 citations

Isolation, characterization, and mapping to chromosome 19 of the human apolipoprotein E gene.

1985 • 352 citations

The β-globin dominant control region activates homologous and heterologous promoters in a tissue-specific manner

1989 • 302 citations

A single erythroid-specific DNase I super-hypersensitive site activates high levels of human beta-globin gene expression in transgenic mice.

1989 • 269 citations

Changes of genetic apolipoprotein phenotypes caused by liver transplantation. Implications for apolipoprotein synthesis.

1989 • 253 citations

High Levels of Human Apolipoprotein A-I in Transgenic Mice Result in Increased Plasma Levels of Small High Density Lipoprotein (HDL) Particles Comparable to Human HDL3

1989 • 238 citations

Apolipoprotein E synthesis in human kidney, adrenal gland, and liver.

1983 • 224 citations

Extrahepatic synthesis of apolipoprotein E.

1984 • 177 citations

Quantitation of apolipoprotein E mRNA in the liver and peripheral tissues of nonhuman primates.

1985 • 147 citations

Two copies of the human apolipoprotein C-I gene are linked closely to the apolipoprotein E gene.

1988 • 134 citations

Systemic distribution of apolipoprotein E secreted by grafts of epidermal keratinocytes: implications for epidermal function and gene therapy.

1989 • 131 citations

Expression of the human apolipoprotein E gene is regulated by multiple positive and negative elements.

1988 • 120 citations

Human apolipoprotein CIII gene expression is regulated by positive and negative cis-acting elements and tissue-specific protein factors.

1988 • 110 citations

Apolipoprotein gene expression in the rabbit: abundance, size, and distribution of apolipoprotein mRNA species in different tissues

1988 • 104 citations

Cell type-specific expression of the human apoB gene is controlled by two cis-acting regulatory regions.

1988 • 69 citations

Structure and expression of dog apolipoprotein A-I, E, and C-I mRNAs: implications for the evolution and functional constraints of apolipoprotein structure.

1989 • 56 citations

A solution hybridization/RNase protection assay with riboprobes to determine absolute levels of apoB, A-I, and E mRNA in human hepatoma cell lines.

1990 • 51 citations

Quantification and regulation of apolipoprotein E expression in rat Kupffer cells.

1989 • 42 citations

Expression of the human apolipoprotein E gene in cultured mammalian cells.

1986 • 29 citations

Exact localization of the familial dysretalipoproteinemia associated HPAI restriction site in the promoter region of the APOC1 gene

1988 • 28 citations