Epithelial cell kinetics. A review of methods of study and their application to oral mucosa in health and disease

ISOLATION OF A TUMOR FACTOR RESPONSIBLE FOR ANGIOGENESIS

1971 • 1,643 citations

Primary Bioassay of Human Tumor Stem Cells

1977 • 1,625 citations

Quantitation of Differential Sensitivity of Human-Tumor Stem Cells to Anticancer Drugs

1978 • 982 citations

Definition of leukoplakia and related lesions: An aid to studies on oral precancer

1978 • 906 citations

The relation between cell proliferation and the vascular system in a transplanted mouse mammary tumour

1968 • 764 citations

A textbook of oral pathology

1975 • 755 citations

Growth Kinetics of Tumours

1978 • 691 citations

Direct cloning of human ovarian carcinoma cells in agar.

1978 • 305 citations

Pretreatment tumor mass, cell kinetics, and prognosis in multiple myeloma

1980 • 269 citations

Growth Kinetics and Biochemical Regulation of Normal and Malignant Cells

1978 • 246 citations

Methotrexate for Psoriasis

1971 • 233 citations

Cell kinetics and chemotherapy: a critical review.

1978 • 224 citations

Oral lichen planus:

1978 • 207 citations

Scientific Foundations of Oncology

1976 • 196 citations

Prognostic Index in Malignant Melanoma

1978 • 192 citations

THE METAPHASE ARREST TECHNIQUE

1980 • 172 citations

Histology and prognosis in malignant melanoma

1969 • 152 citations

Rise and Fall of Cyclic AMP Required for Onset of Lymphocyte DNA Synthesis

1978 • 151 citations

A Mathematical Model of the Mitotic Cycle and Its Application to the Interpretation of Percentage Labeled Mitoses Data<xref ref-type="fn" rid="FN2">2</xref>

1966 • 148 citations

TUMOUR CELL PROLIFERATION IN RELATION TO THE VASCULATURE

1979 • 143 citations

Cell proliferation kinetics in five human solid tumors

1968 • 139 citations

Advanced stage and early relapse of breast carcinomas associated with high thymidine labeling indices.

1979 • 118 citations

Effects of Drugs on the Cell Nucleus

1980 • 118 citations

Cyclic Nucleotides, Calcium, and Cell Division

1977 • 117 citations

Prognostic significance of pretreatment proliferative activity in adult acute leukemia

1977 • 115 citations

Analysis of the cell kinetics of human solid tumors

1971 • 111 citations

Cell proliferation in human basal cell carcinoma.

1970 • 105 citations

Analyses of dna content, nuclear size and cell proliferation of transitional cell carcinoma in man

1969 • 105 citations

The cell cycle in psoriasis: a reappraisal

1976 • 104 citations

Cell proliferation in human melanoma

1970 • 103 citations

Tritiated Thymidine Incorporation Into Epithelial Cells of Normal-Appearing Colorectal Mucosa of Cancer Patients2

1977 • 103 citations

A review of chemotherapy in gastric cancer

1974 • 97 citations

THE RELATIONSHIP BETWEEN DIURNAL VARIATION OF THE NUMBER OF CELLS IN MITOSIS AND OF THE NUMBER OF CELLS SYNTHESIZING DNA IN THE EPITHELIUM OF THE HAMSTER CHEEK POUCH

1968 • 95 citations

CELL CYCLE CHARACTERISTICS OF HUMAN SOLID TUMORS IN VIVO

1970 • 93 citations

Oral cancer: The behaviour and response to treatment of 194 cases

1977 • 90 citations

A Computer-aided Study on the Tissue Changes in Oral Keratoses and Lichen Planus, and an Analysis of Case Groupings by Subjective and Objective Criteria

1970 • 84 citations

Histologic Changes in the Hamster Cheek Pouch During Early Hydrocarbon Carcinogenesis

1957 • 82 citations

Tritiated Thymidine Labeling Index and Response in Human Breast Cancer

1979 • 79 citations

In vitro autoradiographic determination of cell kinetic parameters in adenocarcinomas and adjacent healthy mucosa of the human colon and rectum.

1976 • 77 citations

Prognostic Significance of Ploidy Level in Human Tumors. I. Carcinoma of the Uterus2

1976 • 72 citations

comparison between DNA synthesis and mitosis in uninvolved and involved psoriatic epidermis and normal epidermis

1973 • 71 citations

Prediction of the response to chemotherapy in acute leukemia

1975 • 69 citations

Immunoenhancing Agents and Experimental Leukoplakia and Carcinoma of the Hamster Buccal Pouch1

2015 • 69 citations

Epidermal cell kinetics in lichen planus*

2006 • 68 citations

A COMPARISON OF THE CELL CYCLE IN INDUCED CARCINOMAS AND THEIR NORMAL COUNTERPART.

1964 • 64 citations

LOSS OF EPITHELIAL BLOOD GROUP SUBSTANCE A IN ORAL CARCINOMAS

1973 • 64 citations

The cell proliferation kinetics of psoriasis examined by three in vivo techniques

1976 • 64 citations

Cell kinetics and growth of squamous cell carcinomas in man.

1974 • 63 citations

THE UPTAKE OF 3H-THYMIDINE BY EPIDERMAL CELLS IN NORMAL AND PSORIATIC SUBJECTS..

1966 • 63 citations

Cellular kinetics of invasive squamous carcinoma of the human cervix.

1969 • 61 citations

In vitro determination of tritiated thymidine labeling index (LI).Evaluation of a method utilizing hyperbaric oxygen and observations on the li of human mammary carcinoma

1975 • 61 citations

Prognostic factors in cutaneous malignant melanoma

1974 • 60 citations

In vitro stem cell assay in head and neck squamous carcinoma

1980 • 60 citations

The Use of Discriminant Analysis for Examining the Histological Features of Oral Keratoses and Lichen Planus

1970 • 59 citations

Relationship between the pretreatment proliferative activity of marrow blast cells and prognosis of acute lymphoblastic leukaemia of childhood

1980 • 57 citations

Correlation of cell kinetic and clinical response to chemotherapy in disseminated neuroblastoma.

1977 • 57 citations

Kinetically-based multiple drug treatment for advanced head and neck cancer.

1975 • 57 citations

Autoradiographic analysis of cell kinetics in human normal epidermis and basal cell carcinoma.

1973 • 54 citations

Mitotic rates in the oral and gingival epithelium of the rat

1963 • 52 citations

LOSS OF EPITHELIAL BLOOD GROUP ANTIGENS A AND B IN ORAL PREMALIGNANT LESIONS

1975 • 49 citations

In vitro examination of cell proliferation in normal and psoriatic epidermis, with special regard to diurnal variations

1974 • 48 citations

A comparison of cell proliferation at different sites within the large bowel of the mouse.

1979 • 48 citations

Mitotic Rhythms in Human Cancer, Reevaluated by Electronic Computer Programs—Evidence for Chronopathology2

1966 • 46 citations

Kinetics of Human Epidermal Cell Proliferation: Diurnal Variation**From the Department of Dermatology, University of Miami School of Medicine, Miami, Florida, 33136.

1968 • 45 citations

BIOCHEMICAL and PATHOPHYSIOLOGICAL RATIONALE for AMETHOPTERIN in PSORIASIS*

1971 • 45 citations

TURNOVER OF CELL‐RENEWING POPULATIONS UNDERGOING CIRCADIAN RHYTHMS IN CELL PROLIFERATION

1974 • 45 citations

LABELLING INDEX OF HUMAN SQUAMOUS CELL CARCINOMAS

1979 • 43 citations

Malignant melanoma of the skin: prognostic value of histology in 89 cases

1968 • 43 citations

A retrospective histological study of 669 cases of primary cutaneous malignant melanoma in clinical stage I. 3. The relation between the tumour-associated lymphocyte infiltration and age and sex, tumour cell type, pigmentation, cellular atypia, mitotic count, depth of invasion, ulceration, tumour type and prognosis.

1978 • 42 citations

Cell Population Kinetics in Human Epidermis: In Vitro Autoradiographic Study by Double-Labeling Method

1971 • 42 citations

Cell cycle parameters in human colon.Comparison between primary and recurrent adenocarcinomas, benign polyps and adjacent unaffected mucosa

1977 • 42 citations

Serial labeling index determination as a predictor of response in human solid tumors.

1975 • 41 citations

Effects of Methotrexate on Basal-Cell Carcinomas

1960 • 41 citations

In vivo studies of DNA synthesis in human normal and tumor cells.

1967 • 40 citations

Further Studies on Lesions of the Oral Mucosa Using Computer-Aided Analyses of Histological Features

1974 • 40 citations

Stereological analysis of histological parameters in experimental premalignant hamster cheek pouch epithelium

1980 • 39 citations

The site of mitotic activity in rat and human oral epithelium

1972 • 38 citations

The frequency and distribution of mitotic figures in dysplasia and carcinoma in situ

1977 • 38 citations

Human Tumor Cell Kinetics.

1969 • 37 citations

A CRITICAL REVIEW OF THE USE OF VINCRISTINE (VCR) AS A TUMOUR CELL SYNCHRONIZING AGENT IN CANCER THERAPY

1980 • 37 citations

Progression and regression of cervical lesions: Review of smears from women followed without initial biopsy or treatment

1980 • 36 citations

The reliability of various mitotic index systems in assessing mitotic activity in stratified squamous epithelium

1972 • 35 citations

The effect of chronic frictional stimulation on hamster cheek pouch epithelium

1973 • 35 citations

Immunologic evaluation of patients with advanced head and neck cancer receiving weekly chemoimmunotherapy

1979 • 35 citations

DNA Synthesis Among Uninvolved and Involved Psoriatic Epidermal Cells and Normal Epidermal Cells in Vitro

1978 • 33 citations

Tritiated thymidine labeling index of benign and malignant human breast epithelium

1976 • 33 citations

Feulgen Microspectrophotometry of Oral Cancer and Leukoplakia

1975 • 33 citations

Human tumour karyology: marked analytic improvement by short-term agar culture

1980 • 32 citations

The Clinical Applications of Cell Kinetics in Cancer Therapy

1977 • 32 citations

Cell proliferation and carcinogenesis in the hamster cheek pouch.

1968 • 32 citations

MITOTIC BEHAVIOUR OF THE BUCCAL MUCOSAL EPITHELIUM IN PSORIASIS

1971 • 32 citations

In vitro effects on DNA synthesis as a predictor of biological effect from chemotherapy.

1980 • 30 citations

Studies in Oral Leukoplakias. IV. Mitotic Activity in Oral Leukoplakias: A Preliminary Report

1963 • 30 citations

The measurement of the cell cycle time in squamous epithelium using the metaphase arrest technique with vincristine

1977 • 30 citations

Labelling index in the mucosal lesions of lichen planus

1974 • 29 citations

Cyclic Nucleotides And Epidermal Cell Proliferation

1976 • 29 citations

OBSERVATIONS ON MITOSIS IN PSORIATIC EPIDERMIS

1970 • 29 citations

Oral Mucosa in Health and Disease

1976 • 29 citations

Changes of histological and proliferative indices in the Walker carcinoma with tumour size and distance from blood vessel

1979 • 29 citations

A rapid in vitro labeling index method for predicting response of human solid tumors to chemotherapy.

1976 • 28 citations

Cell Proliferation Kinetics in Normal Human Gastric Mucosa

1976 • 28 citations

Significance of growth rates, cell kinetics, and histology in the irradiation and chemotherapy of squamous cell carcinoma of the mouth

1973 • 27 citations

A correlative analysis of in vitro parameters of cellular immunity in patients with squamous cell carcinoma of the head and neck.

1977 • 27 citations

AN IN VIVO STATHMOKINETIC STUDY OF CELL PROLIFERATION IN HUMAN GASTRIC CARCINOMA AND GASTRIC MUCOSA

1977 • 27 citations

Lack of prognostic significance of the pretreatment labeling and mitotic indices of marrow blasts in acute nonlymphocytic leukemia (ANLL)

1978 • 27 citations

Advanced stage and early relapse of breast carcinomas associated with high thymidine labeling indices

1980 • 26 citations

An in vivo method of studying the kinetics of cell proliferation in normal human epidermis

1974 • 26 citations

The age distribution of cells in stratified squamous epithelium

1977 • 26 citations

The use of colchicine for the assessment of mitotic activity in rat oral epithelium

1972 • 26 citations

Thymidine labeling index of human breast carcinoma:Enhancement of in vitrolabeling by 5-fluorouracil and 5-fluoro-2′ - deoxyuridine

1977 • 25 citations

Stereological quantification of histological parameters in normal hamster cheek pouch epithelium

1978 • 25 citations

In vitro incorporation of tritiated thymidine in oral homogeneous leukoplakias

1972 • 25 citations

Clustering and Control of Mitotic Activity in Human Epidermis

1972 • 24 citations

Decreased rate of DNA-chain growth in human basal cell carcinoma

1980 • 24 citations

Changes in cell cycle characteristics in hamster cheek pouch epithelium during treatment with DMBA

1972 • 24 citations

Results of a low-dose combination chemotherapy with vincristine, bleomycin and methotrexate (V-B-M) based on cell kinetics in the palliative treatment of head and neck squamous cell carcinoma

1980 • 23 citations

The Role of Zinc in Dental Amalgams

1980 • 23 citations

Epithelial cell kinetics – A review of methods of study and their application to oral mucosa in health and disease

1980 • 23 citations

EPIDERMAL CELL KINETICS IN PSORIASIS

1979 • 23 citations

Proliferation kinetics and cyclic amp as prognostic factors in adult acute leukemia

1980 • 22 citations

A rapid in vitro method for measuring cell proliferation in human breast cancer

1977 • 21 citations

Mitoses in normal and psoriatic epidermis

1978 • 21 citations

Cytokinetic evaluation in human head and neck cancer by autoradiography and DNA cytofluorometry

1980 • 21 citations

Correlation between in vitro labeling indices (LIs) and tumor regression following radiotherapy

1978 • 21 citations

The spatial distribution of dividing and DNA‐synthesizing cells in mouse epithelium

1965 • 21 citations

Cellular kinetics and histological changes in experimental cancer of the uterine cervix.

1976 • 21 citations

Regional differences in mitotic activity due to injury in mouse skin

1976 • 20 citations

A rapid in vitro method for measuring cell proliferation in human breast cancer

1977 • 20 citations

XXVI.—THE RELATIVE DURATION OF THE VARIOUS PHASES OF MITOSIS IN CHICK FIBROBLASTS CULTIVATED IN VITRO

1925 • 19 citations

The Mitotic Values for the Epithelium in Oral Keratoses and Lichen Planus

1971 • 19 citations

Spatial Distribution of Cells in Mitotic and DNA-Synthetic Phases of the Cell Cycle in Hamster Cheek Pouch Epithelium

1972 • 19 citations

Human colonic tumor cell kinetics.Potential for therapy

1977 • 18 citations

Some Biological Aspects of Experimental Radiology A Historical Review

1958 • 18 citations

Cell kinetics and programmed chemotherapy for gynecologic cancer

1976 • 18 citations

Stereological quantification of histological parameters in turpentine-induced hyperplasia of hamster cheek pouch epithelium

1978 • 18 citations

Pre-treatment 3H-TdR labelling of cervical biopsies: Histology, staging and tumour response to radiotherapy

1977 • 17 citations

Feulgen microdensitometry and analysis of S-phase cells in cervical tumour biopsies.

1977 • 17 citations

Correlation of DNA distribution and cytological differentiation of human cervical carcinomas

1979 • 16 citations

Mitotic activity in normal and malignant epidermal tissue of the rat.

1956 • 15 citations

Metabolism of [14C]spermidine and [14C]putrescine in normal volunteers and in cancer patients.

1978 • 15 citations

CELL KINETIC ALTERATIONS IN NORMAL AND NEOPLASTIC CELL POPULATIONS IN VITRO AND IN VIVO FOLLOWING VINCRISTINE*. A REPLY TO DR CAMPLEJOHN'S REVIEW ARTICLE^†

1980 • 15 citations

Autoradiographic in vitro studies on diurnal variation in human epidermal cell proliferation

1977 • 15 citations

Studies in oral leukoplakias: XI. Histopathology of Leukoplakias in Indians Chewing “Pan” With Tobacco

1967 • 15 citations

Single dose and short, high dose fractionation radiation therapy for osseous metastases

1978 • 14 citations

Reactive properties of oral lesions to the specific red cell adherence test

1979 • 14 citations

Kinetics of Cell Proliferation in Benign and Premalignant Tumors of the Human Epidermis<xref ref-type="fn" rid="fn2">2</xref>

1975 • 13 citations

The epidermal cell proliferation in lichen planus

1977 • 13 citations

Circadian dependence of host and tumor responses to cyclophosphamide in mice

1978 • 13 citations

Oral Premalignancy: Proceedings of the First Dows Symposium

1981 • 13 citations

Chemical Carcinogenesis in Syrian Hamsters : A Review1 (through 1976)

2015 • 13 citations

A new look at epidermal cell kinetics in psoriasis and other dermatoses

1976 • 13 citations

Rate of Cell Division in Atypias and Invasive Carcinoma of the Uterine Cervix of the Mouse2

1978 • 13 citations

Comparative morphological and histoautoradiographic study of multiple experimental intestinal tumours.

1974 • 12 citations

Diurnal Mitotic Studies of Psoriatic Epidermis

1973 • 12 citations

Vergleichende histologische und histoautoradiographische untersuchungen an benignen oralen leukoplakien

1977 • 11 citations

Mitotic Activity in the Oral Epithelium of the Albino Rat

1976 • 11 citations

In vitro effects on DNA synthesis as a predictor of biological effect from chemotherapy

1981 • 11 citations

A correlative analysis of in vitro parameters of cellular immunity in patients with squamous cell carcinoma of the head and neck

1978 • 10 citations

The use of in vitro methods to predict tumour response to chemotherapy.

1980 • 9 citations

Diurnal Variation in Deoxyribonucleic Acid Synthesis in Selected Epithelial Tissues of Male Rats

1968 • 9 citations

Growth kinetics of squamous cell carcinoma in man. A study of four squamous cell carcinomas using stathmokinetic effect of vinblastine in vivo.

1969 • 9 citations

Mitoses in Human Epidermis

1975 • 9 citations

Diurnal Variation in DNA Synthesis in Hamster Oral Epithelium

1971 • 9 citations

Mitotic Index in Human Squamous Cell Carcinoma

1972 • 8 citations

Diurnal Variation in Epithelial Cell Population Kinetics of Young Mouse Tongue

1977 • 8 citations

The role of cell kinetics in the chemotherapy of hyperproliferative skin diseases

1979 • 8 citations

Spatial distribution of DNA‐synthesizing cells in colonic crypts of the guinea pig

1977 • 8 citations

Ultraviolet Light Carcinogenesis In Hairless Mice: Cell Kinetics During Induction And Progression Of Squamous Cell Carcinoma As Estimated By The Double-Labeling Method

1976 • 8 citations

Cell-kinetical analyses of squamous cell carcinomas of the oral region and the effect of a combined therapy of 5 fluorouracil and irradiation. A contribution to the discussion about tumorcell-synchronization.

1977 • 8 citations

Abnormal epidermal cell proliferation on the elbow in psoriatic and normal skin

1980 • 8 citations

How relevant is the labelling index for cell proliferation

1980 • 8 citations

UNDERSTANDING CHEMOTHERAPY of PSORIASIS IN TERMS of EPIDERMAL CELL PROLIFERATION

1978 • 7 citations

Nonrandom frequency distribution of mitoses in rat lobuloaveolar mammary gland epithelium.

1977 • 7 citations

Changes in cell cycle characteristics in hamster cheek pouch epithelium during treatment with DMBA

1972 • 7 citations

Cytokinetic effects of continuous infusion of vincristine in head and neck carcinoma

1979 • 7 citations

Cell proliferation in human oral mucosa

1976 • 7 citations

The Diagnostic Significance of Nuclear DNA Measurement in Cytologic Smears of Benign and Malignant Gastric Lesions

1978 • 7 citations

Cell Proliferation in Human Cutaneous Squamous Cell Carcinoma23

1977 • 7 citations

Antiepileptic Therapy with Phenytoin: Which Is the Optimum Serum Level?

1979 • 7 citations

Animal model of human disease. Carcinogenesis in the uterine cervix. Animal model: Carcinogenesis in the uterine cervix in mice.

1977 • 7 citations

KINETICS OF EPIDERMAL REACTION TO CARCINOGENS AND OTHER SKIN IRRITANTS

1966 • 7 citations

Oral Leukoplakia

1980 • 6 citations

Incorporation studies of nucleic acid precursors in gastric cancer

1979 • 5 citations

Cell proliferation kinetics in gynecologic cancer.

1977 • 5 citations

The effect of cyclophosphamide upon mitoses in the cornea of rats, a circadian dependent effect

1978 • 5 citations

Cyclic nucleotides and the control of psoriatic cell function.

1980 • 5 citations

Observations on Calcium-Induced Stability of Salivary Proteins in a Lipid-Extraction System

1976 • 4 citations

Measurement of cell production rates in human gastro-intestinal cancer-a guide to treatment?

1975 • 4 citations

CELL KINETICS—WHERE TO NOW?*

1980 • 4 citations

Non‐random spatial distribution of mitoses in proliferating rat uterine epithelium

1978 • 3 citations

Cell kinetics of urethane-induced murine pulmonary adenomas: III. Implications of the disparity between the rates of entry into DNA synthesis and into mitosis

1977 • 3 citations

Patterns of Incorporation of Thymidine in the Female Genital and Other Organs of Mice, Treated with 20-Methylcholanthrene, Estradiol and Ovariectomy

1973 • 1 citations