The reinforcing and subjective effects of morphine in post-addicts: a dose-response study.

Schedules of reinforcement.

1957 • 4,688 citations

Physiologic, subjective, and behavioral effects of amphetamine, methamphetamine, ephedrine, phenmetrazine, and methylphenidate in man

1971 • 946 citations

Experimental Morphine Addiction: Method for Automatic Intravenous Injections in Unrestrained Rats

1962 • 638 citations

Morphine self-administration, food-reinforced, and avoidance behaviors in rhesus monkeys

1964 • 310 citations

Physiological parameters of morphine dependence in man—Tolerance, early abstinence, protracted abstinence

1969 • 264 citations

Implications of Methadone Maintenance for Theories of Narcotic Addiction

1988 • 238 citations

A choice procedure for drug reinforcers: cocaine and methylphenidate in the rhesus monkey.

1975 • 235 citations

Methods for evaluating addiction liability. (A) "Attitude" of opiate addicts toward opiate-like drugs. (B) a short-term "direct" addiction test.

1961 • 228 citations

Cocaine self-administration in humans.

1982 • 169 citations

Cigarette smokers self-administer intravenous nicotine

1983 • 157 citations

A comparative study of physiological and subjective effects of heroin and morphine administered intravenously in postaddicts.

1961 • 153 citations

Reinforcement Properties of Morphine, Cocaine, and SPA as a Function of Unit Dose

1968 • 150 citations

Factors affecting voluntary morphine intake in self-maintained addicted rats

1964 • 147 citations

Opioids: Similarity between evaluations of subjective effects and animal self-administration results

1979 • 127 citations

Internal stimulus control and subjective effects of drugs.

1981 • 100 citations

Human drug self-administration: double-blind comparison of pentobarbital, diazepam, chlorpromazine and placebo.

1979 • 98 citations

Drug addiction. I. Addiction by escape training.

1956 • 97 citations

Behavior maintained under a second-order schedule by intramuscular injection of morphine or cocaine in rhesus monkeys.

1976 • 84 citations

Progressive-ratio performance in the rhesus monkey maintained by opiate infusions

1979 • 76 citations

Behavior maintained under second-order schedules of intravenous morphine injection in squirrel and rhesus monkeys

1977 • 65 citations

Fixed-ratio responding under second-order schedules of food presentation or cocaine injection.

1981 • 64 citations

ORAL DRUG SELF‐ADMINISTRATION IN RHESUS MONKEYS: INTERACTIONS BETWEEN DRUG AMOUNT AND FIXED‐RATIO SIZE

1985 • 63 citations

Apparatus and technique involved in a laboratory method of detecting the addictiveness of drugs

1955 • 56 citations

Comparison of intravenously administered methadone, morphine and heroin

1986 • 55 citations

Classification of narcotics on the basis of their reinforcing, discriminative, and antagonist effects in rhesus monkeys.

1982 • 54 citations

Drug-seeking behavior during methadone maintenance

1975 • 54 citations

Reinforcing properties of oral ? 9-tetrahydrocannabinol, smoked marijuana, and nabilone: Influence of previous marijuana use

1984 • 50 citations

Human progressive-ratio performance: Maintenance by pentobarbital

1983 • 31 citations

The Use of the Polaroid CU Camera in Pupillography

1967 • 31 citations

Comparative evaluation of morphine, pentazocine and ciramadol in postaddicts.

1987 • 29 citations

Choice of blind methadone dose increases by methadone maintenance patients

1986 • 18 citations

Comparison of graded single intramuscular doses of morphine and pentobarbital in man

1974 • 16 citations

Human pharmacology and abuse potential of meptazinol

1987 • 9 citations

Behavioral, physiological and hormonal effects of a naloxone challenge following acute morphine pretreatment in humans.

1988 • 3 citations

REINFORCEMENT OF BEHAVIOR BY MORPHINE INJECTIONS**Supported by U.S. Public Health Service Research Grants DA 01505, DA 00499, MH 07658 and MH 02094 with facilities and services furnished in part by the New England Regional Primate Research Center, Harvard Medical School, Southborough, Massachusetts (U.S. Public Health Service Grant RR 00168, Division of Research Resources, National Institutes of Health). We wish to thank Drs. W.H. Morse, R.T. Kelleher and R.D. Spealman for helpful comments …

1977 • 3 citations

Clinical studies of morphine addiction: Nathan B. Eddy memorial award lecture.

1988 • 2 citations