Human herpesvirus 8 encodes a homolog of interleukin-6

Basic local alignment search tool

1990 • 87,358 citations

Identification of Herpesvirus-Like DNA Sequences in AIDS-Sssociated Kaposi's Sarcoma

1994 • 5,605 citations

Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites

1997 • 5,415 citations

T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines.

1996 • 1,496 citations

Detection of Herpesvirus-Like DNA Sequences in Kaposi's Sarcoma in Patients with and Those without HIV Infection

1995 • 1,093 citations

KSHV antibodies among Americans, Italians and Ugandans with and without Kaposi's sarcoma

1996 • 816 citations

The seroepidemiology of human herpesvirus 8 (Kaposi's sarcoma–associated herpesvirus): Distribution of infection in KS risk groups and evidence for sexual transmission

1996 • 763 citations

DETECTION OF HERPESVIRUS-LIKE DNA SEQUENCES IN KAPOSI'S SARCOMA IN PATIENTS WITH AND THOSE WITHOUT HIV INFECTION

1995 • 682 citations

Primary characterization of a herpesvirus agent associated with Kaposi's sarcomae

1996 • 573 citations

AIDS Kaposi sarcoma-derived cells produce and respond to interleukin 6.

1990 • 500 citations

Human herpesvirus-like nucleic acid in various forms of Kaposi's sarcoma

1995 • 444 citations

Primary structure of the herpesvirus saimiri genome

1992 • 440 citations

Herpesvirus-like DNA sequences in patients with Mediterranean Kaposi's sarcoma

1995 • 380 citations

Oncostatin M as a Potent Mitogen for AIDS-Kaposi's Sarcoma-Derived Cells

1992 • 251 citations

The expression of the interleukin 6 gene is induced by the human immunodeficiency virus 1 TAT protein.

1994 • 250 citations

Kaposi's Sarcoma-Associated Herpesvirus and Kaposi's Sarcoma in Africa

1996 • 178 citations

Kaposi's sarcoma-associated herpesvirus and Kaposi's sarcoma in Africa. Uganda Kaposi's Sarcoma Study Group

1996 • 132 citations

Virus-encoded cyclin.

1994 • 131 citations

Structure-function analysis of interleukin-6 utilizing human/murine chimeric molecules. Involvement of two separate domains in receptor binding

1993 • 111 citations

Herpesvirus saimiri has a gene specifying a homologue of the cellular membrane glycoprotein CD59

1992 • 108 citations

New member of the multigene family of complement control proteins in herpesvirus saimiri

1992 • 99 citations

[10] Finding protein coding regions in genomic sequences

1990 • 84 citations

Identification of interleukin-1 and platelet-derived growth factor-B as major mitogens for the spindle cells of Kaposi's sarcoma: a combined in vitro and in vivo analysis.

1995 • 83 citations

Herpesvirus-like DNA sequences and Kaposi's sarcoma: Relationship with epidemiology, clinical spectrum, and histologic features

1996 • 77 citations

Oncostatin-M is an autocrine growth factor in Kaposi's sarcoma.

1994 • 76 citations

A Gene for Dihydrofolate Reductase in a Herpesvirus

1988 • 73 citations

Oncostatin-M stimulates tyrosine protein phosphorylation in parallel with the activation of p42MAPK/ERK-2 in Kaposi's cells. Evidence that this pathway is important in Kaposi cell growth.

1993 • 64 citations

Virus-Encoded Cyclin

1994 • 56 citations

Herpesvirus-like DNA Sequences in Non-AIDS Kaposi's Sarcoma

1995 • 51 citations

AIDS-associated Kaposi's sarcoma (KS) cells express oncostatin M (OM)-specific receptor but not leukemia inhibitory factor/OM receptor or interleukin-6 receptor. Complete block of OM-induced KS cell growth and OM binding by anti-gp130 antibodies.

1995 • 51 citations

Induction of IL-6 gene expression in Kaposi's sarcoma cells.

1994 • 48 citations

A Comparative Analysis of the Sequence of the Thymidine Kinase Gene of a Gammaherpesvirus, Herpesvirus Saimiri

1989 • 39 citations

Inhibition of AIDS-Associated Kaposi's Sarcoma Cell Growth by DAB₃₈₉-Interleukin 6

1994 • 34 citations

Effects of Interleukin-1 and Interleukin-1 Receptor Antagonist in AIDS-Kaposiʼs Sarcoma

1995 • 31 citations

Correlation of oncostatin M secretion by human retrovirus-infected cells with potent growth stimulation of cultured spindle cells from AIDS-Kaposi's sarcoma.

1993 • 29 citations

HIV-1 infection and modulation of cytokine and growth factor expression in Kaposiʼs sarcoma-derived cells in vitro

1993 • 21 citations

Pathogenesis of human immunodeficiency virus-related Kaposiʼs sarcoma

1992 • 18 citations

Comparison of Constitutive Cytokine Release in High and Low Histologic Grade AIDS-Related Kaposi's Sarcoma Cell Strains and in Sera from HIV⁺/KS⁺and HIV⁺/KS^-Patients

1995 • 15 citations

A receptor-binding peptide from human interleukin-6: Isolation and a proton nuclear magnetic resonance study

1992 • 14 citations

Residues 77‐95 of the Human Interleuken‐6 Protein are Responsible for Receptor Binding and Residues 41‐56 for Signal Transduction

1995 • 5 citations