Mechanisms of Activation of Regulatory Volume Responses After Cell Swelling

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Elastic Properties of Lipid Bilayers: Theory and Possible Experiments

1973 • 5,817 citations

Inositol trisphosphate and diacylglycerol as second messengers

1984 • 3,535 citations

INOSITOL TRISPHOSPHATE AND DIACYLGLYCEROL: TWO INTERACTING SECOND MESSENGERS

1987 • 3,302 citations

Single-Channel Recording

1995 • 2,565 citations

A model for receptor-regulated calcium entry

1986 • 2,535 citations

Muscarinic activation of ionic currents measured by a new whole-cell recording method.

1988 • 1,777 citations

The Kidney: Physiology and Pathophysiology

1992 • 1,714 citations

The potassium permeability of a giant nerve fibre

1955 • 1,094 citations

Intracellular phospholipases A

1980 • 989 citations

Stretch-activated single ion channel currents in tissue-cultured embryonic chick skeletal muscle.

1984 • 987 citations

Membrane mechanisms in volume and pH regulation in vertebrate cells

1989 • 880 citations

Block of Stretch-Activated Ion Channels in Xenopus Oocytes by Gadolinium and Calcium Ions

1989 • 811 citations

Single stretch-activated ion channels in vascular endothelial cells as mechanotransducers?

1987 • 703 citations

The Kidney: Physiology and Pathophysiology.

1985 • 665 citations

Conduction and selectivity in potassium channels

1983 • 665 citations

Pressure-sensitive ion channel in Escherichia coli.

1987 • 646 citations

A transient calcium‐dependent chloride current in the immature Xenopus oocyte.

1983 • 627 citations

Altered Regulation of Airway Epithelial Cell Chloride Channels in Cystic Fibrosis

1986 • 568 citations

Patch clamp measurements onXenopus laevis oocytes: currents through endogenous channels and implanted acetylcholine receptor and sodium channels

1986 • 534 citations

Cytosolic Ca2+ homeostasis in Ehrlich and Yoshida carcinomas. A new, membrane-permeant chelator of heavy metals reveals that these ascites tumor cell lines have normal cytosolic free Ca2+.

1985 • 489 citations

Thermoelasticity of large lecithin bilayer vesicles

1981 • 480 citations

Elastic area compressibility modulus of red cell membrane

1976 • 447 citations

Water movement through lipid bilayers, pores, and plasma membranes : theory and reality

1987 • 441 citations

Responses of lymphocytes to anisotonic media: volume-regulating behavior

1984 • 427 citations

Calcium and Cell Function

1982 • 421 citations

Mediation of cell volume regulation by Ca2+ influx through stretch-activated channels

1987 • 418 citations

Chloride current induced by injection of calcium into Xenopus oocytes.

1984 • 395 citations

Anisosmotic cell volume regulation: a comparative view

1989 • 394 citations

A Mechanosensitive Ion Channel in the Yeast Plasma Membrane

1988 • 382 citations

Osmoregulatory Salt Transporting Mechanisms: Control of Cell Volume in Anisotonic Media

1981 • 360 citations

Volume regulation by Amphiuma red blood cells. The membrane potential and its implications regarding the nature of the ion-flux pathways.

1980 • 359 citations

PHARMACOLOGICAL REGULATION OF CALMODULIN*

1980 • 341 citations

Erythrocyte Anion Exchange and the Band 3 Protein: Transport Kinetics and Molecular Structure

1979 • 340 citations

Calmodulin stimulates human platelet phospholipase A2

1979 • 309 citations

Osmotic Behaviour of the Epithelial Cells of Frog Skin

1961 • 297 citations

Erythrocyte Membrane Elasticity and Viscosity

1987 • 291 citations

CA2+-Activated K+ Channels in Erythrocytes and Excitable Cells

1983 • 250 citations

Passive potassium transport in low potassium sheep red cells: dependence upon cell volume and chloride.

1981 • 249 citations

A calcium‐activated chloride current generates the after‐depolarization of rat sensory neurones in culture.

1985 • 239 citations

The role of phosphoinositiees in signal transduction

1986 • 225 citations

A Possible Role for Taurine in Osmoregulation Within the Brain

1988 • 223 citations

Ca2+ sensitivity of volume‐regulatory K+ and Cl‐ channels in cultured human epithelial cells.

1988 • 223 citations

Urinary concentrating ability: insights from comparative anatomy

1985 • 222 citations

The Alkali Metal Ions in Biology

1960 • 217 citations

Volume-induced increase of K+ and Cl− permeabilities in Ehrlich ascites tumor cells. Role of internal Ca2+

1984 • 211 citations

Calcium and cell function

1983 • 207 citations

Volume regulation by human lymphocytes. Role of calcium.

1982 • 204 citations

Volume-induced increase of anion permeability in human lymphocytes.

1982 • 202 citations

Transport Processes, Iono- and Osmoregulation

1985 • 199 citations

Activation of ion transport systems during cell volume regulation

1987 • 195 citations

Stretch-Inactivated Ion Channels Coexist with Stretch-Activated Ion Channels

1989 • 192 citations

Volume, pH, and ion-content regulation in human red cells: Analysis of transient behavior with an integrated model

1986 • 192 citations

Incorporation of cytoplasmic vesicles into apical membrane of mammalian urinary bladder epithelium

1982 • 189 citations

A chloride dependent K+ flux induced by N-ethylmaleimide in genetically low K+ sheep and goat erythrocytes

1980 • 182 citations

Diphenylamine-2-carboxylate, a blocker of the Cl−-conductive pathway in Cl−-transporting epithelia

1985 • 181 citations

THE ROLE OF CARBONIC ANHYDRASE IN CERTAIN IONIC EXCHANGES INVOLVING THE ERYTHROCYTE

1942 • 179 citations

Human erythrocyte anion permeabilities measured under conditions of net charge transfer

1977 • 172 citations

Separate, Ca2+-activated K+ and Cl− transport pathways in Ehrlich ascites tumor cells

1986 • 170 citations

Calcium and polyphosphoinositide control of cytoskeletal dynamics

1989 • 168 citations

A Ca-dependent Cl− conductance in cultured mouse spinal neurones

1984 • 165 citations

Involvement of calcium and cytoskeleton in gallbladder epithelial cell volume regulation

1985 • 160 citations

K+:Cl− Cotransport: Sulfhydryls, divalent cations, and the mechanism of volume activation in a red cell

1985 • 154 citations

Voltage‐activated and stretch‐activated Ba²⁺ conducting channels in an osteoblast‐like cell line (UMR 106)

1989 • 149 citations

Properties of non‐junctional acetylcholine receptor channels on innervated muscle of Xenopus laevis.

1984 • 146 citations

A stretch-activated K+ channel sensitive to cell volume.

1989 • 146 citations

Cell swelling activates K+ and Cl? channels as well as nonselective, stretch-activated cation channels in ehrlich ascites tumor cells

1992 • 145 citations

Ion channels activated by osmotic and mechanical stress in membranes of opossum kidney cells

1988 • 143 citations

Volume regulation of frog skin epithelium

1982 • 141 citations

Electrophysiology of Pancreatic and Salivary Acinar Cells

1988 • 140 citations

Adaptation of mouse leukemic cells (L5178Y) to anisotonic media

1973 • 132 citations

The Response of Duck Erythrocytes to Hypertonic Media

1971 • 131 citations

Evidence for the presence of volume-sensitive KCl transport in ‘young’ human red cells

1986 • 131 citations

Membrane transport processes

1980 • 130 citations

DRIVING FORCES OF AMINO ACID TRANSPORT IN ANIMAL CELLS^fn1

1975 • 130 citations

Cell volume regulation in ehrlich ascites tumor cells

1974 • 128 citations

A cation channel in frog lens epithelia responsive to pressure and calcium

1986 • 126 citations

Ca2+-activated K+ channels in human red cells. Comparison of single-channel currents with ion fluxes

1984 • 126 citations

Isovolumetric regulation of isolated S2 proximal tubules in anisotonic media.

1986 • 125 citations

Role of intracellular calcium in cellular volume regulation

1986 • 125 citations

Anion-dependent cation transport in erythrocytes

1982 • 123 citations

Cell volume regulation by Amphiuma red blood cells. The role of Ca+2 as a modulator of alkali metal/H+ exchange.

1983 • 122 citations

Interaction of the cytoskeleton with the plasma membrane

1987 • 121 citations

Role of prostaglandins and leukotrienes in volume regulation by Ehrlich ascites tumor cells

1987 • 118 citations

Stretch Activation of a K+ Channel in Molluscan Heart Cells

1987 • 117 citations

Stretch-activated current through single ion channels in the abdominal stretch receptor organ of the crayfish.

1989 • 116 citations

Biophysics of Mechanoreception

1986 • 116 citations

Activity of ion channels during volume regulation by clonal N1E115 neuroblastoma cells.

1989 • 115 citations

Baroreceptor mechanisms at the cellular level.

1987 • 111 citations

Cell swelling increases a barium-inhibitable potassium conductance in the basolateral membrane of Necturus small intestine.

1984 • 109 citations

Membrane potential, chloride exchange, and chloride conductance in Ehrlich mouse ascites tumour cells.

1979 • 109 citations

Mechanotransducer ion channels in chick skeletal muscle: the effects of extracellular pH.

1985 • 107 citations

Potassium and Chloride Channels in Red Blood Cells

1983 • 106 citations

Evidence for chloride dependent potassium and water transport induced by hyposmotic stress in erythrocytes of the marine teleost,Opsanus tau

1982 • 106 citations

Volume Regulation in Cultured Cells

1987 • 104 citations

Gap junctions and direct intercellular communication between rat uterine smooth muscle cells

1985 • 104 citations

Sodium Transport Inhibition by Amiloride Reduces Basolateral Membrane Potassium Conductance in Tight Epithelia

1982 • 103 citations

Control of cell volume and ion transport by beta‐adrenergic catecholamines in erythrocytes of rainbow trout, Salmo gairdneri.

1987 • 101 citations

Potassium Channels in Excitable and Non-excitable Cells

1990 • 100 citations

Volume regulation byNecturus gallbladder: Basolateral KCl exit

1984 • 99 citations

Effect of anisotonic media on volume, ion and amino-acid content and membrane potential of kidney cells (MDCK) in culture

1987 • 98 citations

The Role of the Electrochemical Gradient in Determining Potassium Fluxes in Frog Striated Muscle

1968 • 96 citations

Cell Volume Regulation

1998 • 96 citations

Role of calcium in volume regulation by dog red blood cells.

1975 • 95 citations

Molecular neurobiology; a practical approach

1992 • 92 citations

Effects of Ca2+ and furosemide on Cl- transport and O2 uptake in rat parotid acini

1986 • 90 citations

Stretch-activated cation channels in human fibroblasts

1988 • 90 citations

Volume Regulation in Cells of Euryhaline Invertebrates

1987 • 88 citations

Stretch-activated potassium channels in renal proximal tubule

1987 • 88 citations

Volume regulation by human lymphocytes: Characterization of the ionic basis for regulatory volume decrease

1982 • 87 citations

Volume restoration in osmotically swollen lymphocytes does not involve changes in free Ca2+ concentration

1983 • 86 citations

Effect of adenosine 3',5'-cyclic monophosphate on volume and cytoskeleton of MDCK cells

1986 • 85 citations

Kinetic properties of the pentobarbitone‐gated chloride current in frog sensory neurones.

1987 • 85 citations

Volume-regulatory K+ efflux during concentrative uptake of alanine in isolated rat hepatocytes

1984 • 84 citations

Swelling of astrocytes causes membrane potential depolarization

1988 • 84 citations

Cellular Acclimatisation to Environmental Change

1983 • 84 citations

Activation by N-ethylmaleimide of a latent K+-Cl- flux in human red blood cells

1984 • 82 citations

Hypotonic shock evokes opening of Ca2+-activated K channels in opossum kidney cells

1988 • 81 citations

Man in stressful environments : thermal and work physiology

1987 • 79 citations

Ionic events during the volume response of human peripheral blood lymphocytes to hypotonic media. I. Distinctions between volume-activated Cl- and K+ conductance pathways.

1984 • 79 citations

Ischemic renal injury.

1976 • 77 citations

Sodium-coupled glycine uptake by Ehrlich ascites tumor cells results in an increase in cell volume and plasma membrane channel activities.

1988 • 75 citations

Volume regulation by red blood cells. Mechanisms of ion transport between cells and mechanisms

1983 • 74 citations

Characterization of volume-sensitive, calcium-permeating pathways in the osteosarcoma cell line UMR-106-01

1989 • 73 citations

Membrane potential, anion and cation conductances in Ehrlich ascites tumor cell

1989 • 71 citations

Volume regulation and basolateral co-transport of sodium, potassium, and chloride ions in frog skin epithelium

1985 • 71 citations

Effect of arachidonic acid, fatty acids, prostaglandins, and leukotrienes on volume regulation in Ehrlich ascites tumor cells

1987 • 69 citations

Hysteretic activation of the Ca2+ pump revealed by calcium transients in human red cells

1983 • 68 citations

Dog Red Blood Cells

1973 • 67 citations

Cation and anion transport pathways in volume regulatory response of human lymphocytes to hyposmotic media

1985 • 67 citations

Volume‐regulating behavior of human platelets

1987 • 67 citations

Sodium and potassium transport in trout (Salmo gairdneri) erythrocytes.

1984 • 66 citations

Ouabain-resistant mechanism of volume control and the ultrastructural organization of liver slices recovering from swellingin vitro

1981 • 63 citations

Activation of Cl-dependent K transport in Ehrlich ascites tumor cells

1986 • 61 citations

Cytoplasmic acidification and activation of Na+/H+ exchange during regulatory volume decrease in Ehrlich ascites tumor cells

1990 • 57 citations

Increased anion permeability during volume regulation in human lymphocytes

1982 • 57 citations

Volume regulation by Amphiuma red blood cells: cytosolic free Ca and alkali metal-H exchange

1986 • 57 citations

Regulatory volume decrease in perfused proximal nephron: evidence for a dumping of cell K+

1987 • 56 citations

Effect of barium on cell volume regulation in rabbit proximal straight tubules

1985 • 56 citations

Cell volume regulation in rabbit proximal straight tubule perfused in vitro

1987 • 55 citations

Single-file diffusion through the Ca2+-activated K+ channel of human red cells

1985 • 54 citations

K-Permeabilized human red cells lose an alkaline, hypertonic fluid containing excess K over diffusible anions

1987 • 53 citations

Ionic requirement for regulatory cell volume decrease in renal straight proximal tubules

1988 • 53 citations

Stretch-activated ion channels modulate the resting membrane potential during early embryogenesis

1988 • 51 citations

Measurement of osmolality in kidney slices using vapor pressure osmometry

1982 • 51 citations

Ionic events during the volume response of human peripheral blood lymphocytes to hypotonic media. II. Volume- and time-dependent activation and inactivation of ion transport pathways.

1984 • 51 citations

The Duck Red Cell Model of Volume‐Sensitive Chloride‐Dependent Cation Transport

1985 • 51 citations

Stretch-activated ion channels in bacteria and animal cell membranes

1987 • 50 citations

Inactivation of the renal microvillus membrane Na+-H+ exchanger by histidine-specific reagents.

1986 • 50 citations

A nonselective cation channel activated by membrane deformation in oocytes of the ascidianBoltenia villosa

1989 • 49 citations

Osmotic behavior of normal and leukemic lymphocytes

1975 • 49 citations

Associations between transports of alanine and cations across cell membrane in rat hepatocytes

1986 • 47 citations

Role of separate K+ and Cl- channels and of Na+/Cl- cotransport in volume regulation in Ehrlich cells.

1985 • 46 citations

EPITHELIAL CELL VOLUME REGULATION IN HYPOTONIC FLUIDS: STUDIES USING A MODEL TISSUE CULTURE RENAL EPITHELIAL CELL SYSTEM

1984 • 46 citations

Mechanisms in Volume Regulation in Ehrlich Ascites Tumor Cells

1988 • 46 citations

The effect of hypoosmolarity on the electrical properties of Madin Darby canine kidney cells

1989 • 43 citations

The number of chloride-cation cotransport sites on Ehrlich ascites cells measured with [3H]bumetanide

1986 • 42 citations

Purification of proteins of the Na/Cl cotransporter from membranes of Ehrlich ascites cells using a bumetanide-sepharose affinity column

1988 • 42 citations

The Cell Cytoskeleton: Possible Role in Volume Control

1987 • 39 citations

Cell volume regulation in frog urinary bladder.

1985 • 39 citations

Induction of ⁸⁶Rb Fluxes by Ca²⁺ and volume changes in thymocytes and their isolated membranes

1983 • 38 citations

Volume regulation by Amphiuma red blood cells: strategies for identifying alkali metal/H+ transport.

1985 • 38 citations

Volume regulation by Amphiuma red blood cells: characteristics of volume-sensitive K/H and Na/H exchange

1985 • 38 citations

Dog red blood cells: Na and K diffusion potentials with extracellular ATP.

1977 • 37 citations

Study of microfilaments network during volume regulation process of cultured PC 12 cells

1987 • 36 citations

Is the red cell calcium pump electrogenic?

1982 • 36 citations

Chapter 5 Volume-Sensitive Alkali Metal-H Transport in Amphiuma Red Blood Cells

1986 • 35 citations

Regulatory volume decrease by cultured renal cells

1989 • 32 citations

Ca2+-dependent K+ transport in the Ehrlich ascites tumor cell

1982 • 31 citations

Evidence for the involvement of calmodulin in the operation of Ca-activated K channels in mouse fibroblasts

1987 • 30 citations

The effect of cytochalasin B on the volume regulation response of isolated axons of the green crab Carcinus maenas submitted to hypo-osmotic media

1986 • 30 citations

Passive calcium movements in dog red blood cells: anion effects

1983 • 29 citations

Volume Preservation: Then and Now

1989 • 28 citations

Effects of A23187 and Ca2+ on volume- and thiol-stimulated, ouabain-resistant K+Cl− fluxes in low K+ sheep erythrocytes

1984 • 28 citations

A high-affinity, calmodulin-sensitive (Ca2+ + Mg2+)-ATPase and associated calcium-transport pump in the Ehrlich ascites tumor cell plasma membrane

1983 • 28 citations

Calcium permeability of Ehrlich ascites tumour cell plasma membrane in vivo

1982 • 27 citations

Receptors Subserving Hunger and Thirst

1972 • 26 citations

Volume Regulation in Epithelia

1987 • 24 citations

Stimulation of NaCl secretion in the rectal gland of the dogfish Squalus acanthias

1988 • 24 citations

Electrophysiological Studies of Sodium Cotransport in Epithelia: Toward a Cellular Model^a

1985 • 22 citations

Cell Volume Control: Fundamental and Comparative Aspects in Animal Cells

1987 • 22 citations

Effect of metabolic inhibitors on renal tubule cell volume

1980 • 21 citations

Multi-Ion Nature of Potassium Channels in Squid Axons

1984 • 20 citations

Effect of ouabain and colloid osmotic pressure on renal tubule cell volume

1978 • 20 citations

Chapter 8 The Generation of Ionic Signals by Growth Factors

1986 • 18 citations

Simultaneous recording of cell volume, membrane current and membrane potential: effect of hypotonic shock

1989 • 18 citations

Indacrinone (MK‐196) ‐ a specific inhibitor of the voltage‐dependent CI‐ permeability in toad skin

1986 • 16 citations

Volume-activated transport systems in dog red blood cells

1988 • 16 citations

The control of ion channels and pumps in exocrine acinar cells

1988 • 14 citations

Chapter 2 Intracellular Sodium Activities and Basolateral Membrane Potassium Conductances of Sodium-Absorbing Epithelial Cells

1989 • 14 citations

Anion exchange and volume regulation during metabolic blockade of renal cortical slices.

1979 • 14 citations

Electrical properties of Ehrlich ascites tumor cells

1987 • 14 citations

Sodium cotransport systems in epithelial secretion

1988 • 13 citations

Volume-Sensitive Passive Potassium Fluxes in Red Cells

1985 • 12 citations

ELECTROPHYSIOLOGY OF CELL VOLUME REGULATION

1987 • 12 citations

Single-file diffusion through K+ channels in frog skin epithelium

1986 • 11 citations

CELLULAR RESPONSE TO INJURY

1938 • 5 citations

Deleted Work

1955 • 0 citations