Characterization of the human lipoprotein lipase (LPL) promoter: evidence of two cis-regulatory regions, LP-alpha and LP-beta, of importance for the differentiation-linked induction of the LPL gene during adipogenesis.

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DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

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A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.

1987 • 4,937 citations

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

1982 • 2,753 citations

Establishment and characterization of a human acute monocytic leukemia cell line (THP‐1)

1980 • 2,158 citations

Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells.

1991 • 1,684 citations

Tissue-specific in vitro transcription from the mouse albumin promoter

1986 • 1,322 citations

NUCLEASE HYPERSENSITIVE SITES IN CHROMATIN

1988 • 1,233 citations

Spontaneous heritable changes leading to increased adipose conversion in 3T3 cells

1976 • 826 citations

Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro

1985 • 805 citations

A novel rapid assay for chloramphenicol acetyltransferase gene expression

1987 • 802 citations

The homeotic gene fork head encodes a nuclear protein and is expressed in the terminal regions of the Drosophila embryo

1989 • 760 citations

CCAAT-Enhancer Binding Protein: A Component of a Differentiation Switch

1991 • 733 citations

Cell-Specific Expression of the Rat Insulin Gene: Evidence for Role of Two Distinct 5′ Flanking Elements

1985 • 698 citations

An absolute method for protein determination based on difference in absorbance at 235 and 280 nm

1980 • 592 citations

Differentiation-induced gene expression in 3T3-L1 preadipocytes: CCAAT/enhancer binding protein interacts with and activates the promoters of two adipocyte-specific genes.

1989 • 587 citations

Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and alpha 1-antitrypsin genes.

1989 • 545 citations

Hepatocyte nuclear factor 3 alpha belongs to a gene family in mammals that is homologous to the Drosophila homeotic gene fork head.

1991 • 517 citations

Insulin-like growth factor-I is an essential regulator of the differentiation of 3T3-L1 adipocytes.

1988 • 506 citations

Human Lipoprotein Lipase Complementary DNA Sequence

1987 • 484 citations

Mouse insulin-responsive glucose transporter gene: characterization of the gene and trans-activation by the CCAAT/enhancer binding protein.

1990 • 287 citations

Formation of normally differentiated subcutaneous fat pads by an established preadipose cell line

1979 • 282 citations

An exonuclease protection assay reveals heat-shock element and TATA box DNA-binding proteins in crude nuclear extracts

1985 • 280 citations

Sterol-dependent repression of low density lipoprotein receptor promoter mediated by 16-base pair sequence adjacent to binding site for transcription factor Sp1.

1988 • 271 citations

Structure of the human lipoprotein lipase gene

1989 • 224 citations

Organization of the human lipoprotein lipase gene and evolution of the lipase gene family.

1989 • 223 citations

A direct role for C/EBP and the AP-I-binding site in gene expression linked to adipocyte differentiation.

1989 • 170 citations

Studies of lipoprotein lipase during the adipose conversion of 3T3 cells

1978 • 165 citations

The CCAAT/enhancer binding protein and its role in adipocyte differentiation: evidence for direct involvement in terminal adipocyte development.

1991 • 161 citations

Evidence for a complex regulatory array in the first intron of the human adenosine deaminase gene.

1989 • 124 citations

Molecular cloning and sequence analysis of cDNA encoding lipoprotein lipase of guinea pig

1987 • 109 citations

Tissue-specific regulation of guinea pig lipoprotein lipase; effects of nutritional state and of tumor necrosis factor on mRNA levels in adipose tissue, heart and liver

1988 • 98 citations

Coupling of growth arrest and expression of early markers during adipose conversion of preadipocyte cell lines

1986 • 72 citations

Nucleotide sequence and hormonal regulation of mouse glycerophosphate dehydrogenase mRNA during adipocyte and muscle cell differentiation.

1987 • 69 citations

Mouse c-mos oncogene activation is prevented by upstream sequences.

1984 • 60 citations

Expression and regulation of pOb24 and lipoprotein lipase genes during adipose conversion

1990 • 56 citations

Transcriptional regulation of the human lipoprotein lipase gene in 3T3-L1 adipocytes.

1991 • 55 citations

Sequences Upstream from the Mousec-mosOncogene May Function as a Transcription Termination Signal

1986 • 54 citations

Synthesis of lipoprotein lipase in the liver of newborn rats and localization of the enzyme by immunofluorescence

1988 • 50 citations

Lipoprotein lipase gene expression in THP-1 cells

1989 • 43 citations

Cloning and characterization of the promoter of the murine lipoprotein lipase-encoding gene: structural and functional analysis

1991 • 42 citations

Negative and positive promoter elements contribute to tissue specificity of apolipoprotein B expression

1989 • 41 citations

Human Immunoglobulin κ Gene Enhancer: Chromatin Structure Analysis at High Resolution

1987 • 30 citations

B-cell nuclear proteins binding in vitro to the human immunoglobulin kappa enhancer: localization by exonuclease protection.

1987 • 23 citations