Identification of a Glutathione-S-Transferase Effector Domain for Inhibition of jun Kinase, by Molecular Dynamics

Structure and energetics of ligand binding to proteins: Escherichia coli dihydrofolate reductase‐trimethoprim, a drug‐receptor system

1988 • 1,947 citations

Glutathione Transferases—Structure and Catalytic Activit

1988 • 1,751 citations

Regulation of JNK signaling by GSTp

1999 • 1,102 citations

Energy parameters in polypeptides. 9. Updating of geometrical parameters, nonbonded interactions, and hydrogen bond interactions for the naturally occurring amino acids

1983 • 947 citations

Theta, a new class of glutathione transferases purified from rat and man

1991 • 743 citations

Insulin induction of Xenopus laevis oocyte maturation is inhibited by monoclonal antibody against p21 ras proteins.

1987 • 183 citations

Molecular Structure at 1·8 Å of Mouse Liver Class Pi Glutathione S-transferase Complexed with S-(p-Nitrobenzyl)glutathione and Other Inhibitors

1994 • 130 citations

Molecular dynamics simulations of native and substrate-bound lysozyme

1986 • 112 citations

Complexes of p21RAS with JUN N-terminal kinase and JUN proteins.

1995 • 74 citations

Activation of c-Jun-NH2-Kinase by UV Irradiation Is Dependent on p21

1996 • 72 citations

Isozyme specificity of novel glutathione-S-transferase inhibitors

1993 • 59 citations

Monoclonal antibodies to glutathione S‐Transferase π–immunohistochemical analysis of human tissues and cancers

1991 • 55 citations

Glutathione-S-Transferase as a selective inhibitor of oncogenic ras-p21-induced mitogenic signaling through blockade of activation of jun by jun-N-terminal kinase.

2000 • 40 citations

ras-p21-Induced Cell Transformation: Unique Signal Transduction Pathways and Implications for the Design of New Chemotherapeutic Agents

2000 • 38 citations

Comparison of the low energy conformations of an oncogenic and a non-oncogenic p21 protein, neither of which binds GTP or GDP

1994 • 30 citations

Selective inhibition of oncogenic ras- p21 in vivo by agents that block its interaction with jun -N-kinase (JNK) and jun proteins. Implications for the design of selective chemotherapeutic agents

1997 • 26 citations

Comparison of the computed three-dimensional structures of oncogenic forms (bound to GDP) of theras-Gene-Encoded p21 protein with the structure of the normal (non-transforming) wild-type protein

1995 • 19 citations

Structural effects of the binding of GTP to the wild-type and oncogenic forms of theras-gene-encoded p21 proteins

1995 • 17 citations

Computed three-dimensional structures for theras-binding domain of theraf-p74 protein complexed withras-p21 and with its suppressor protein, rap-1A

1996 • 8 citations